metH:On One Page

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

Quickview

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<protect>

Standard Name

metH

Gene Synonym(s)

ECK4011, b4019, JW3979[1], JW3979

Product Desc.

Methionine synthase, cobalamin-dependent; 5-methyltetrahydrofolate-homocysteine methyltransferase; binds Zn(II)[2]

Product Synonyms(s)

homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent[1], B4019[3][1], MetH[3][1] , ECK4011, JW3979, b4019

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): metH[3], OP00055

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

</protect> See Help:Quickview for help with entering information in the Quickview table. <protect></protect>

Notes

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Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

metH

Mnemonic

Methionine

Synonyms

ECK4011, b4019, JW3979[1], JW3979

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

90.99 minutes 

MG1655: 4221851..4225534
<gbrowseImage> name=NC_000913:4221851..4225534 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 4202759..4206442
<gbrowseImage> name=NC_012967:4202759..4206442 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 4111531..4115214
<gbrowseImage> name=NC_012759:4111531..4115214 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 4227418..4231101
<gbrowseImage> name=NC_007779:4227418..4231101 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 4321547..4325230
<gbrowseImage> name=NC_010473:4321547..4325230 source=DH10B preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

Coding Start (SO:0000323)

MG1655

4221854

Edman degradation

PMID:2668277


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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

ΔmetH (Keio:JW3979)

deletion

deletion

PMID:16738554

Shigen
CGSC10862[4]

metHC310A,S

C310A,S

Loss of zinc binding. Loss of catalytic activity

seeded from UniProt:P13009

metHC311A,S

C311A,S

Loss of zinc binding. Loss of catalytic activity

seeded from UniProt:P13009

metHD757E

D757E

Decreases activity by about 70%

seeded from UniProt:P13009

metHD757N

D757N

Decreases activity by about 45%

seeded from UniProt:P13009

metHH759G

H759G

Loss of catalytic activity

seeded from UniProt:P13009

metHS810A

S810A

Decreases activity by about 40%

seeded from UniProt:P13009

metH156

PMID:4579870

CGSC:9164

ΔmetH786::kan

PMID:16738554

CGSC:101834


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Notes

Genetic Interactions

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<protect>

Interactor Interaction Allele Score(s) Reference(s) Accessions Notes

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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW3979

Plasmid clone

Shigen

PMID:16769691

Status:Clone OK

Primer 1:GCCAGCAGCAAAGTGGAACAACT

Primer 2:CCGTCCGCGTCATACCCCAGATT

6G10

Kohara Phage

Genobase

PMID:3038334

4E5

Kohara Phage

Genobase

PMID:3038334

thiC39::Tn10

Linked marker

CAG18500 = CGSC7472[4]

est. P1 cotransduction: 35% [5]
Synonyms:thi-39::Tn10

malF3089::Tn10

Linked marker

CAG12164 = CGSC7476[4]

est. P1 cotransduction: 51% [5]

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10587

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10587

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000580

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:948522

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0582

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013140

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MetH

Synonyms

homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent[1], B4019[3][1], MetH[3][1] , ECK4011, JW3979, b4019

Product description

Methionine synthase, cobalamin-dependent; 5-methyltetrahydrofolate-homocysteine methyltransferase; binds Zn(II)[2]

EC number (for enzymes)

<protect></protect>

Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0004156

dihydropteroate synthase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000489

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004223

C

Seeded from EcoCyc (v14.0)

complete

GO:0008168

methyltransferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0489

F

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0862

F

Seeded from EcoCyc (v14.0)

complete

GO:0008652

cellular amino acid biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0028

P

Seeded from EcoCyc (v14.0)

complete

GO:0008705

methionine synthase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003759

F

Seeded from EcoCyc (v14.0)

complete

GO:0008705

methionine synthase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004223

F

Seeded from EcoCyc (v14.0)

complete

GO:0008705

methionine synthase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011822

F

Seeded from EcoCyc (v14.0)

complete

GO:0008705

methionine synthase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.1.1.13

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

PMID:9250984

IDA: Inferred from Direct Assay

C

complete

GO:0008898

homocysteine S-methyltransferase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003726

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

PMID:2668277

IDA: Inferred from Direct Assay

C

complete

GO:0009086

methionine biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003759

P

Seeded from EcoCyc (v14.0)

complete

GO:0008705

methionine synthase activity

PMID:10978155

IDA: Inferred from Direct Assay

F

complete

GO:0009086

methionine biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004223

P

Seeded from EcoCyc (v14.0)

complete

GO:0008168

methyltransferase activity

Taylor and Weissbach (1971)[6]

IDA: Inferred from Direct Assay

F

Missing: reference

GO:0009086

methionine biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011822

P

Seeded from EcoCyc (v14.0)

complete

GO:0008898

homocysteine S-methyltransferase activity

Taylor and Weissbach (1971)[6]

IDA: Inferred from Direct Assay

F

Missing: reference

GO:0009086

methionine biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0486

P

Seeded from EcoCyc (v14.0)

complete

GO:0009257

10-formyltetrahydrofolate biosynthetic process

Taylor and Weissbach (1971)[6]

IDA: Inferred from Direct Assay

P

Missing: reference

GO:0009396

folic acid and derivative biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000489

P

Seeded from EcoCyc (v14.0)

complete

GO:0008705

methionine synthase activity

Taylor and Weissbach (1971)[6]

IDA: Inferred from Direct Assay

F

Missing: reference

GO:0031419

cobalamin binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003759

F

Seeded from EcoCyc (v14.0)

complete

GO:0008652

cellular amino acid biosynthetic process

Taylor and Weissbach (1971)[6]

IDA: Inferred from Direct Assay

P

Missing: reference

GO:0031419

cobalamin binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006158

F

Seeded from EcoCyc (v14.0)

complete

GO:0009086

methionine biosynthetic process

Taylor and Weissbach (1971)[6]

IDA: Inferred from Direct Assay

P

Missing: reference

GO:0031419

cobalamin binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011822

F

Seeded from EcoCyc (v14.0)

complete

GO:0031419

cobalamin binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0846

F

Seeded from EcoCyc (v14.0)

complete

GO:0044237

cellular metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011005

P

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003759

F

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006158

F

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc (v14.0)

complete

GO:0050897

cobalt ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011822

F

Seeded from EcoCyc (v14.0)

complete

GO:0050897

cobalt ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0170

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

gltB

PMID:16606699

Experiment(s):EBI-1147304

Protein

dnaE

PMID:16606699

Experiment(s):EBI-1147304

Protein

ilvC

PMID:16606699

Experiment(s):EBI-1147304

Protein

bglX

PMID:16606699

Experiment(s):EBI-1147304

Small Molecule

Cobalamin

PMID:9201956


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MSSKVEQLRA QLNERILVLD GGMGTMIQSY RLNEADFRGE RFADWPCDLK GNNDLLVLSK
PEVIAAIHNA YFEAGADIIE TNTFNSTTIA MADYQMESLS AEINFAAAKL ARACADEWTA
RTPEKPRYVA GVLGPTNRTA SISPDVNDPA FRNITFDGLV AAYRESTKAL VEGGADLILI
ETVFDTLNAK AAVFAVKTEF EALGVELPIM ISGTITDASG RTLSGQTTEA FYNSLRHAEA
LTFGLNCALG PDELRQYVQE LSRIAECYVT AHPNAGLPNA FGEYDLDADT MAKQIREWAQ
AGFLNIVGGC CGTTPQHIAA MSRAVEGLAP RKLPEIPVAC RLSGLEPLNI GEDSLFVNVG
ERTNVTGSAK FKRLIKEEKY SEALDVARQQ VENGAQIIDI NMDEGMLDAE AAMVRFLNLI
AGEPDIARVP IMIDSSKWDV IEKGLKCIQG KGIVNSISMK EGVDAFIHHA KLLRRYGAAV
VVMAFDEQGQ ADTRARKIEI CRRAYKILTE EVGFPPEDII FDPNIFAVAT GIEEHNNYAQ
DFIGACEDIK RELPHALISG GVSNVSFSFR GNDPVREAIH AVFLYYAIRN GMDMGIVNAG
QLAIYDDLPA ELRDAVEDVI LNRRDDGTER LLELAEKYRG SKTDDTANAQ QAEWRSWEVN
KRLEYSLVKG ITEFIEQDTE EARQQATRPI EVIEGPLMDG MNVVGDLFGE GKMFLPQVVK
SARVMKQAVA YLEPFIEASK EQGKTNGKMV IATVKGDVHD IGKNIVGVVL QCNNYEIVDL
GVMVPAEKIL RTAKEVNADL IGLSGLITPS LDEMVNVAKE MERQGFTIPL LIGGATTSKA
HTAVKIEQNY SGPTVYVQNA SRTVGVVAAL LSDTQRDDFV ARTRKEYETV RIQHGRKKPR
TPPVTLEAAR DNDFAFDWQA YTPPVAHRLG VQEVEASIET LRNYIDWTPF FMTWSLAGKY
PRILEDEVVG VEAQRLFKDA NDMLDKLSAE KTLNPRGVVG LFPANRVGDD IEIYRDETRT
HVINVSHHLR QQTEKTGFAN YCLADFVAPK LSGKADYIGA FAVTGGLEED ALADAFEAQH
DDYNKIMVKA LADRLAEAFA EYLHERVRKV YWGYAPNENL SNEELIRENY QGIRPAPGYP
ACPEHTEKAT IWELLEVEKH TGMKLTESFA MWPGASVSGW YFSHPDSKYY AVAQIQRDQV
EDYARRKGMS VTEVERWLAP NLGYDAD
Length

1,227

Mol. Wt

135.998 kDa

pI

4.8 (calculated)

Extinction coefficient

136,600 - 138,225 (calc based on 40 Y, 14 W, and 13 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P13009

Domain

747..851

PF02310 B12 binding domain

PMID:19920124

Domain

657..740

PF02607 B12 binding domain

PMID:19920124

Domain

1055..1192

PF02965 Vitamin B12 dependent methionine synthase, activation domain

PMID:19920124

Domain

356..568

PF00809 Pterin binding enzyme

PMID:19920124

Domain

16..327

PF02574 Homocysteine S-methyltransferase

PMID:19920124

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=metH taxon=562,83333 </beststructure>

Models

View models at:

</protect>

Structure figures

<protect>

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

<protect></protect>

Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131845

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948522

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013140

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P13009

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10587

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10587

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948522

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000580

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0582

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Protein

E. coli K-12 MC4100

1.24E+02

molecules/cell

  • Medium: median data from rich and minimal media
  • Temperature (°C): 37
  • Doubling time (min): Growth Rate(min):
  • Growth phase: other:

emPAI

PMID:18304323

Protein

E. coli K-12 MG1655

559

molecules/cell/generation

  • Medium: MOPS Complete
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

753

molecules/cell/generation

  • Medium: MOPS Minimal
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

1780

molecules/cell/generation

  • Medium: MOPS Complete without Methionine
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Notes

Transcription and Transcriptional Regulation

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<protect>

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

metH

Figure courtesy of RegulonDB

</protect>

Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000913:4221831..4221871 source=MG1655 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

</protect>

Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

</protect>

Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference


Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b4019 (EcoliWiki Page)

NCBI GEO profiles for metH

microarray

GenExpDB:b4019 (EcoliWiki Page)

Summary of data for metH from multiple microarray studies


Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes

<protect></protect>

Notes

Accessions Related to metH Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10587

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0582

Escherichia coli str. K-12 substr. MG1655

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b4019

EcoGene

EcoGene:EG10587

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000580

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013140

Escherichia coli str. K-12 substr. MG1655

<protect></protect>

Notes

Links

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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments

Anopheles gambiae

  • ENSANGP00000027053 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Bos taurus

  • ENSBTAP00000016262 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Caenorhabditis briggsae

  • WBGene00039583 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Caenorhabditis elegans

  • WBGene00010988 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Canis familiaris

  • ENSCAFP00000015753 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Ciona intestinalis

  • ENSCINP00000017964 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Danio rerio

  • ZDB-GENE-031001-5 (score: 1.000; bootstrap: 100%)
  • ZDB-CDNA-040425-557 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Dictyostelium discoideum

  • DDB0230138 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Gallus gallus

  • ENSGALP00000023311 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Homo sapiens

  • ENSP00000264178 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Macaca mulatta

  • ENSMMUP00000013174 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Monodelphis domestica

  • ENSMODP00000009254 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Mus musculus

  • MGI:894292 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Pan troglodytes

  • ENSPTRP00000003622 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Rattus norvegicus

  • ENSRNOP00000023973 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Takifugu rubripes

  • NEWSINFRUP00000175300 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Tetraodon nigroviridis

  • GSTENP00010412001 (score: 1.000; bootstrap: 87%)

From Inparanoid:20070104

Xenopus tropicalis

  • ENSXETP00000039980 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Shigella flexneri

METH

From SHIGELLACYC

E. coli O157

METH

From ECOO157CYC


Do-It-Yourself Web Tools

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Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

Pfam (EcoliWiki Page)

PF02310 B12 binding domain

Pfam (EcoliWiki Page)

PF02607 B12 binding domain

Pfam (EcoliWiki Page)

PF02965 Vitamin B12 dependent methionine synthase, activation domain

Superfamily (EcoliWiki Page)

SUPERFAMILY:47644

Superfamily (EcoliWiki Page)

SUPERFAMILY:51717

Superfamily (EcoliWiki Page)

SUPERFAMILY:52242

Panther (EcoliWiki Page)

PTHR21091:SF9

Superfamily (EcoliWiki Page)

SUPERFAMILY:56507

Superfamily (EcoliWiki Page)

SUPERFAMILY:82282

Pfam (EcoliWiki Page)

PF00809 Pterin binding enzyme

Pfam (EcoliWiki Page)

PF02574 Homocysteine S-methyltransferase

EcoCyc

EcoCyc:EG10587

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10587

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000580

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0582

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013140

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 CGSC: The Coli Genetics Stock Center
  5. 5.0 5.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
  6. 6.0 6.1 6.2 6.3 6.4 6.5 Taylor, R.T. and Weissbach, H. NS-methyltetrahydrofolate-homocysteine (Vitamin B12) methyltransferase (Escherichia coli B). Methods Enzymol. 17B (1971) 379-388.Taylor & Weissbach Cite error: Invalid <ref> tag; name "Taylor" defined multiple times with different content Cite error: Invalid <ref> tag; name "Taylor" defined multiple times with different content Cite error: Invalid <ref> tag; name "Taylor" defined multiple times with different content Cite error: Invalid <ref> tag; name "Taylor" defined multiple times with different content Cite error: Invalid <ref> tag; name "Taylor" defined multiple times with different content

Categories

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