PMID:18003906
| Citation |
Frank, J, Gao, H, Sengupta, J, Gao, N and Taylor, DJ (2007) The process of mRNA-tRNA translocation. Proc. Natl. Acad. Sci. U.S.A. 104:19671-8 |
|---|---|
| Abstract |
In the elongation cycle of translation, translocation is the process that advances the mRNA-tRNA moiety on the ribosome, to allow the next codon to move into the decoding center. New results obtained by cryoelectron microscopy, interpreted in the light of x-ray structures and kinetic data, allow us to develop a model of the molecular events during translocation. |
| Links |
PubMed PMC2148355 Online version:10.1073/pnas.0708517104 |
| Keywords |
Animals; Biological Transport; Catalysis; Guanosine Triphosphate/metabolism; Humans; Hydrolysis; Models, Genetic; Peptide Elongation Factor G/chemistry; Peptide Elongation Factor G/metabolism; RNA, Messenger/chemistry; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Messenger/ultrastructure; RNA, Transfer/chemistry; RNA, Transfer/genetics; RNA, Transfer/metabolism; RNA, Transfer/ultrastructure; Ribosomes/chemistry; Ribosomes/metabolism |
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