mutM:On One Page

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

Quickview

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

<protect>

Standard Name

mutM

Gene Synonym(s)

ECK3625, b3635, JW3610, fpg[1], fpg

Product Desc.

formamidopyrimidine DNA glycosylase[2][3]

Formamidopyrimidine-DNA glycosylase/AP lyase; 5'-terminal deoxyribophosphodiesterase; DNA repair; GC to TA; binds Zn(II)[4]

Product Synonyms(s)

formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase[1], B3635[2][1], Fpg[2][1], MutM[2][1] , ECK3625, fpg, JW3610, b3635

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mutM[2], rpmBG-mutM[2], yicR-rpmBG-mutM[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

edit table

</protect> See Help:Quickview for help with entering information in the Quickview table. <protect></protect>

Notes

[back to top]





Gene

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css> <protect>

Nomenclature

[back to top]


See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

mutM

Mnemonic

Mutator

Synonyms

ECK3625, b3635, JW3610, fpg[1], fpg

edit table

</protect>

Notes

Location(s) and DNA Sequence

[back to top]


<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

82.08 minutes 

MG1655: 3809175..3808366
<gbrowseImage> name=NC_000913:3808366..3809175 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 3749507..3748698
<gbrowseImage> name=NC_012967:3748698..3749507 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 3696692..3697501
<gbrowseImage> name=NC_012759:3696692..3697501 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 3829263..3830072
<gbrowseImage> name=NC_007779:3829263..3830072 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 3906752..3905943
<gbrowseImage> name=NC_010473:3905943..3906752 source=DH10B preset=GeneLocation </gbrowseImage>

edit table

</protect>

Notes

Sequence Features

[back to top]


See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

Coding Start (SO:0000323)

MG1655

3808369

Edman degradation

PMID:3319582


edit table

<protect></protect>

Notes

Alleles and Phenotypes

[back to top]


See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

mutM(del) (Keio:JW3610)

deletion

deletion

PMID:16738554

Shigen

mutM::Tn5KAN-I-SceI (FB21352)

Insertion at nt 312 in Plus orientation

PMID:15262929

E. coli Genome Project:FB21352

contains pKD46

mutM::Tn5KAN-I-SceI (FB21353)

Insertion at nt 312 in Plus orientation

PMID:15262929

E. coli Genome Project:FB21353

does not contain pKD46

mutMK218T

K218T

Slight increase of substrate affinity and decrease of activity

seeded from UniProt:P05523

mutME174Q

E174Q

Strong decrease of glycosylase activity; slight decrease of AP lyase activity

seeded from UniProt:P05523

mutME3Q

E3Q

Strong decrease of glycosylase activity; slight decrease of AP lyase activity

seeded from UniProt:P05523

mutME6Q

E6Q

Decrease of glycosylase activity; no effect on AP lyase activity

seeded from UniProt:P05523

mutMH90A

H90A

Increase of substrate affinity and decrease of activity

seeded from UniProt:P05523

mutMD107N

D107N

No effect on glycosylase and AP lyase activity

seeded from UniProt:P05523

mutMR109A

R109A

Over 100-fold decrease of activity

seeded from UniProt:P05523

mutMR110A

R110A

Over 100-fold increase of substrate affinity and decrease of activity

seeded from UniProt:P05523

mutME132Q

E132Q

Decrease of glycosylase activity; slight decrease of AP lyase activity

seeded from UniProt:P05523

mutMD160N

D160N

No effect on glycosylase and AP lyase activity

seeded from UniProt:P05523

mutM102::kan

PMID:8676878

CGSC:67990

mutM103::mini-Tn10

PMID:8676878

CGSC:67993


edit table

<protect></protect>

Notes

Genetic Interactions

[back to top]


<protect>

Interactor Interaction Allele Score(s) Reference(s) Accessions Notes
edit table

</protect>

Notes

Genetic Resources

[back to top]


See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW3610

Plasmid clone

Shigen

PMID:16769691

Status:Clone OK

Primer 1:GCCCCTGAATTACCCGAAGTTGA

Primer 2:CCtTTCTGGCACTGCCGACAATA

2A6

Kohara Phage

Genobase

PMID:3038334

4D2

Kohara Phage

Genobase

PMID:3038334

zhg-50::Tn10

Linked marker

CAG18450 = CGSC7450[5]

est. P1 cotransduction: % [6]
Synonyms:zhf-50::Tn10, zhf-5::Tn10

zic-4901::Tn10

Linked marker

CAG18492 = CGSC7457[5]

est. P1 cotransduction: 50% [6]

edit table

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10329

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10329

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000323

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:946765

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0325

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011877

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]



Product(s)

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MutM

Synonyms

formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase[1], B3635[2][1], Fpg[2][1], MutM[2][1] , ECK3625, fpg, JW3610, b3635

Product description

formamidopyrimidine DNA glycosylase[2][3]

Formamidopyrimidine-DNA glycosylase/AP lyase; 5'-terminal deoxyribophosphodiesterase; DNA repair; GC to TA; binds Zn(II)[4]

EC number (for enzymes)
edit table

<protect></protect>

Notes

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0019104

DNA N-glycosylase activity

PMID:2664776

IDA: Inferred from Direct Assay

F

complete

GO:0004519

endonuclease activity

PMID:2664776

IDA: Inferred from Direct Assay

F

nicking at AP sites

complete

GO:0003676

nucleic acid binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010979

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015887

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0003684

damaged DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012319

F

Seeded from EcoCyc (v14.0)

complete

GO:0003684

damaged DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015886

F

Seeded from EcoCyc (v14.0)

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00103

F

Seeded from EcoCyc (v14.0)

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000191

F

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

PMID:8473347

IDA: Inferred from Direct Assay

F

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000214

F

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

PMID:8473347

IDA: Inferred from Direct Assay

F

Cu(II), Cd(II), Hg(II) bind the protein

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012319

F

Seeded from EcoCyc (v14.0)

complete

GO:0019104

DNA N-glycosylase activity

PMID:8473347

IDA: Inferred from Direct Assay

F

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015886

F

Seeded from EcoCyc (v14.0)

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

PMID:8473347

IDA: Inferred from Direct Assay

F

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015887

F

Seeded from EcoCyc (v14.0)

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:4.2.99.18

F

Seeded from EcoCyc (v14.0)

complete

GO:0006974

response to DNA damage stimulus

PMID:1731864

IDA: Inferred from Direct Assay

P

complete

GO:0006281

DNA repair

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00103

P

Seeded from EcoCyc (v14.0)

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

PMID:1731864

IDA: Inferred from Direct Assay

F

complete

GO:0004519

endonuclease activity

PMID:8473347

IDA: Inferred from Direct Assay

F

complete

GO:0006281

DNA repair

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000191

P

Seeded from EcoCyc (v14.0)

complete

GO:0019104

DNA N-glycosylase activity

PMID:1649454

EXP: Inferred from Experiment

F

complete

GO:0006281

DNA repair

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000214

P

Seeded from EcoCyc (v14.0)

complete

GO:0004519

endonuclease activity

PMID:1649454

EXP: Inferred from Experiment

F

complete

GO:0004519

endonuclease activity

PMID:1731864

IDA: Inferred from Direct Assay

F

complete

GO:0006281

DNA repair

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015887

P

Seeded from EcoCyc (v14.0)

complete

GO:0006281

DNA repair

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020629

P

Seeded from EcoCyc (v14.0)

complete

GO:0019104

DNA N-glycosylase activity

PMID:10862773

IDA: Inferred from Direct Assay

F

complete

GO:0006281

DNA repair

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0234

P

Seeded from EcoCyc (v14.0)

complete

GO:0003684

damaged DNA binding

PMID:10862773

IDA: Inferred from Direct Assay

F

complete

GO:0006284

base-excision repair

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012319

P

Seeded from EcoCyc (v14.0)

complete

GO:0006289

nucleotide-excision repair

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015886

P

Seeded from EcoCyc (v14.0)

complete

GO:0006974

response to DNA damage stimulus

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0227

P

Seeded from EcoCyc (v14.0)

complete

GO:0008152

metabolic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0326

P

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000191

F

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000214

F

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012319

F

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015886

F

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015887

F

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020629

F

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0862

F

Seeded from EcoCyc (v14.0)

complete

GO:0008534

oxidized purine base lesion DNA N-glycosylase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00103

F

Seeded from EcoCyc (v14.0)

complete

GO:0008534

oxidized purine base lesion DNA N-glycosylase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000191

F

Seeded from EcoCyc (v14.0)

complete

GO:0008534

oxidized purine base lesion DNA N-glycosylase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020629

F

Seeded from EcoCyc (v14.0)

complete

GO:0008534

oxidized purine base lesion DNA N-glycosylase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.2.2.23

F

Seeded from EcoCyc (v14.0)

complete

GO:0016829

lyase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0456

F

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

PMID:8473347

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

glpT

PMID:16606699

Experiment(s):EBI-1146365

Protein

thiI

PMID:16606699

Experiment(s):EBI-1146365

Protein

ilvI

PMID:16606699

Experiment(s):EBI-1146365

Protein

mscL

PMID:19402753

LCMS(ID Probability):98.9

Small Molecule

PMPS

Inhibitor

PMID:8473347

Activity Assays

edit table

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
edit table

<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MPELPEVETS RRGIEPHLVG ATILHAVVRN GRLRWPVSEE IYRLSDQPVL SVQRRAKYLL
LELPEGWIII HLGMSGSLRI LPEELPPEKH DHVDLVMSNG KVLRYTDPRR FGAWLWTKEL
EGHNVLTHLG PEPLSDDFNG EYLHQKCAKK KTAIKPWLMD NKLVVGVGNI YASESLFAAG
IHPDRLASSL SLAECELLAR VIKAVLLRSI EQGGTTLKDF LQSDGKPGYF AQELQVYGRK
GEPCRVCGTP IVATKHAQRA TFYCRQCQK
Length

269

Mol. Wt

30.29 kDa

pI

8.6 (calculated)

Extinction coefficient

39,420 - 40,170 (calc based on 8 Y, 5 W, and 6 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P05523

Domain

2..115

PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain

PMID:19920124

Domain

241..269

PF06827 Zinc finger found in FPG and IleRS

PMID:19920124

Domain

129..220

PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain

PMID:19920124

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mutM taxon=562,83333 </beststructure>

Models

View models at:

edit table
</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131506

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946765

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011877

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P05523

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10329

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10329

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946765

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000323

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0325

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]




Expression

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

[back to top]


See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Protein

Ecoli K-12

1.208+/-0.056

Molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): *
  • Growth phase: other: *

Single Molecule Fluorescence

PMID:20671182

mRNA

Ecoli K-12

0.012360939

Molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): *
  • Growth phase: other: *

by RNA_Seq

PMID:20671182

Protein

E. coli K-12 MG1655

684

molecules/cell/generation

  • Medium: MOPS Complete
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

86

molecules/cell/generation

  • Medium: MOPS Minimal
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

511

molecules/cell/generation

  • Medium: MOPS Complete without Methionine
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

edit table

Notes

Transcription and Transcriptional Regulation

[back to top]


<protect>

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

mutM

rpmBG-mutM

yicR-rpmBG-mutM

edit table
Figure courtesy of RegulonDB

</protect>

Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

[back to top]


<protect><gbrowseImage> name=NC_000913:3809155..3809195 source=MG1655 flip=1 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

</protect>

Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

</protect>

Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

[back to top]


<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference
edit table


Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b3635 (EcoliWiki Page)

NCBI GEO profiles for mutM

microarray

GenExpDB:b3635 (EcoliWiki Page)

Summary of data for mutM from multiple microarray studies

edit table


Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes

GFP Fusion

Intergenic region (3808710..3808899) fused to gfpmut2.

OpenBioSystems

GFP fusion described in Zaslaver, et al.
Plate:109-AZ12; Well:F6[7]

edit table

<protect></protect>

Notes

Accessions Related to mutM Expression

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10329

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0325

Escherichia coli str. K-12 substr. MG1655

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b3635

EcoGene

EcoGene:EG10329

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000323

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011877

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]



Evolution

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Homologs in Other Organisms

[back to top]


See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments

Arabidopsis thaliana

  • AT1G52500 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Oryza gramene

  • Q69RX3 (score: 1.000; bootstrap: 100%)
  • Q6UU93 (score: 0.875)
  • Q67WP0 (score: 0.438)
  • Q761Y8 (score: 0.280)

From Inparanoid:20070104

Xenopus tropicalis

  • ENSXETP00000033641 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Shigella flexneri

MUTM

From SHIGELLACYC

E. coli O157

MUTM

From ECOO157CYC

edit table


Do-It-Yourself Web Tools

<protect></protect>

Notes

Families

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

Pfam (EcoliWiki Page)

PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain

Superfamily (EcoliWiki Page)

SUPERFAMILY:46946

Superfamily (EcoliWiki Page)

SUPERFAMILY:57716

Superfamily (EcoliWiki Page)

SUPERFAMILY:81624

Pfam (EcoliWiki Page)

PF06827 Zinc finger found in FPG and IleRS

Pfam (EcoliWiki Page)

PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain

EcoCyc

EcoCyc:EG10329

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10329

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000323

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0325

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011877

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]



References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 CGSC: The Coli Genetics Stock Center
  6. ↑ 6.0 6.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
  7. ↑ Zaslaver, A et al. (2006) A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Nat. Methods 3 623-8 PubMed

Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=mutM:On_One_Page&oldid=222024"