mukB:On One Page

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

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Standard Name

mukB

Gene Synonym(s)

ECK0915, b0924, JW0907[1], JW0907

Product Desc.

cell division protein involved in chromosome partitioning[2][3];

Component of MukB-MukE-MukF complex[3]

Chromosome condensin MukBEF, ATPase and DNA-binding subunit[4]

Product Synonyms(s)

fused chromosome partitioning protein: predicted nucleotide hydrolase[1], conserved protein[1], B0924[2][1], MukB[2][1] , ECK0915, JW0907, b0924

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): smtA-mukFEB[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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Condensin is required for chromosome partitioning and compaction. Purified MukB and Topo II introduces right-handed knots into DNA. Coiled coil protein.[4]



Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

mukB

Mnemonic

Mukaku (anucleate)

Synonyms

ECK0915, b0924, JW0907[1], JW0907

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

21.03 minutes 

MG1655: 975549..980009
<gbrowseImage> name=NC_000913:975549..980009 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 993418..997878
<gbrowseImage> name=NC_012967:993418..997878 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 878517..882977
<gbrowseImage> name=NC_012759:878517..882977 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 976748..981208
<gbrowseImage> name=NC_007779:976748..981208 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 1029477..1033937
<gbrowseImage> name=NC_010473:1029477..1033937 source=DH10B preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

Coding Start (SO:0000323)

MG1655

975549

Edman degradation

PMID:1464330


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Notes

Nucleotide sequence of the gene and its putative promoter/ RBS is discussed in reference[5].

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

mukB::Tn5KAN-2 (FB20251)

Insertion at nt 4399 in Minus orientation

temperature sensitive

PMID:15262929

E. coli Genome Project:FB20251

does not contain pKD46

mukBM1428L

M1428L

No effect

seeded from UniProt:P22523

mukBS33F

S33F

In mukB106; no effect

seeded from UniProt:P22523

mukBQ1429R

Q1429R

Abolishes association with mukE and mukF, but still binds DNA

seeded from UniProt:P22523

mukBK40L

K40L

No effect

seeded from UniProt:P22523

mukBD1201N

D1201N

In mukB33; no effect

seeded from UniProt:P22523

mukBV1381L

V1381L

Abolishes DNA-binding, but remains associated with mukE and mukF

seeded from UniProt:P22523

mukBL1403P

L1403P

Abolishes association with mukE and mukF, but still binds DNA

seeded from UniProt:P22523

mukBF1404L

F1404L

No effect

seeded from UniProt:P22523

mukBD1406N

D1406N

No effect

seeded from UniProt:P22523

ΔmukB ftsK1::cat

deletion

deletion

Growth Phenotype

synthetically lethal

PMID:9829960

ΔmukB:kan

deletion

deletion

Growth Phenotype

  • aberrant chromosome partitioning at low temp
  • cannot form colonies at high temp (ts)
  • nucleoids irregularly distributed along elongated cells

PMID:1989883


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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes
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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW0907

Plasmid clone

Shigen

PMID:16769691

Status:Clone OK

Primer 1:GCCATTGAACGCGGTAAATTTCG

Primer 2:CCACTCGCCTGAGAAGGCGCTTC

E1D1

Kohara Phage

Genobase

PMID:3038334

zca-1230::Tn10

Linked marker

CAG18478 = CGSC7356[6]

est. P1 cotransduction: 32% [7]
Synonyms:zbj-1230::Tn10

zcb-3059::Tn10

Linked marker

CAG12094 = CGSC7358[6]

est. P1 cotransduction: 36% [7]

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10618

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10618

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000611

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:945549

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0613

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003138

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MukB

Synonyms

fused chromosome partitioning protein: predicted nucleotide hydrolase[1], conserved protein[1], B0924[2][1], MukB[2][1] , ECK0915, JW0907, b0924

Product description

cell division protein involved in chromosome partitioning[2][3];

Component of MukB-MukE-MukF complex[3]

Chromosome condensin MukBEF, ATPase and DNA-binding subunit[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0000796

condensin complex

PMID:16740950

IMP: Inferred from Mutant Phenotype

C

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01800

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007406

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012090

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01800

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007406

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012090

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01800

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0006260

DNA replication

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01800

P

Seeded from EcoCyc (v14.0)

complete

GO:0007049

cell cycle

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0131

P

Seeded from EcoCyc (v14.0)

complete

GO:0007059

chromosome segregation

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01800

P

Seeded from EcoCyc (v14.0)

complete

GO:0007059

chromosome segregation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007406

P

Seeded from EcoCyc (v14.0)

complete

GO:0007059

chromosome segregation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012090

P

Seeded from EcoCyc (v14.0)

complete

GO:0007059

chromosome segregation

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0159

P

Seeded from EcoCyc (v14.0)

complete

GO:0007059

chromosome segregation

PMID:1989883

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc (v14.0)

complete

GO:0009295

nucleoid

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007406

C

Seeded from EcoCyc (v14.0)

complete

GO:0009295

nucleoid

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012090

C

Seeded from EcoCyc (v14.0)

complete

GO:0009295

nucleoid

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0187

C

Seeded from EcoCyc (v14.0)

complete

GO:0030261

chromosome condensation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007406

P

Seeded from EcoCyc (v14.0)

complete

GO:0030261

chromosome condensation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012090

P

Seeded from EcoCyc (v14.0)

complete

GO:0030261

chromosome condensation

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0226

P

Seeded from EcoCyc (v14.0)

complete

GO:0051301

cell division

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0132

P

Seeded from EcoCyc (v14.0)

complete

GO:0007062

regulation of sister chromatid cohesion

PMID:14517265

IMP: Inferred from Mutant Phenotype

P

complete

GO:0007059

chromosome segregation

PMID:14517265

IMP: Inferred from Mutant Phenotype

P

complete

GO:0007059

chromosome segregation

PMID:17824928

IMP: Inferred from Mutant Phenotype

P

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of MukB-MukE-MukF complex

could be indirect

Protein

mukE

PMID:15690043

Experiment(s):EBI-889622, EBI-889696, EBI-894594, EBI-894643

Protein

mukF

PMID:15690043

Experiment(s):EBI-889622, EBI-894594

Protein

parC

PMID:15690043

Experiment(s):EBI-889622

Protein

rplB

PMID:15690043

Experiment(s):EBI-889622

Protein

rplC

PMID:15690043

Experiment(s):EBI-889622

Protein

rplD

PMID:15690043

Experiment(s):EBI-889622

Protein

rplM

PMID:15690043

Experiment(s):EBI-889622, EBI-894594

Protein

rpsB

PMID:15690043

Experiment(s):EBI-889622, EBI-894594

Protein

rpsC

PMID:15690043

Experiment(s):EBI-889622

Protein

rpsJ

PMID:15690043

Experiment(s):EBI-889622, EBI-894594

Protein

tufA

PMID:15690043

Experiment(s):EBI-889622, EBI-894594

Protein

yciH

PMID:16606699

Experiment(s):EBI-1138378

Protein

rpsI

PMID:16606699

Experiment(s):EBI-1138378

Protein

rplB

PMID:16606699

Experiment(s):EBI-1138378

Protein

prs

PMID:16606699

Experiment(s):EBI-1138378

Protein

rplQ

PMID:16606699

Experiment(s):EBI-1138378

Protein

rplI

PMID:16606699

Experiment(s):EBI-1138378

Protein

rplL

PMID:15690043

Experiment(s):EBI-894594

Protein

rplR

PMID:15690043

Experiment(s):EBI-894594

Protein

rplV

PMID:15690043

Experiment(s):EBI-894594

Protein

rpmB

PMID:15690043

Experiment(s):EBI-894594

Protein

rpsE

PMID:15690043

Experiment(s):EBI-894594

Protein

rpsG

PMID:15690043

Experiment(s):EBI-894594

Protein

rpsP

PMID:15690043

Experiment(s):EBI-894594

Protein

rplR

PMID:19402753

LCMS(ID Probability):99.6

Protein

rpmB

PMID:19402753

LCMS(ID Probability):99.6

Protein

rpsP

PMID:19402753

LCMS(ID Probability):99.6

Protein

tufB

PMID:19402753

MALDI(Z-score):27.233960

Protein

rplM

PMID:19402753

LCMS(ID Probability):99.6 MALDI(Z-score):17.053160

Protein

rpsJ

PMID:19402753

LCMS(ID Probability):99.6 MALDI(Z-score):17.053160

Protein

rpsD

PMID:19402753

MALDI(Z-score):25.609987

Protein

rplB

PMID:19402753

MALDI(Z-score):30.252750

Protein

acpP

PMID:19402753

LCMS(ID Probability):99.6 MALDI(Z-score):10.425110

Protein

mukF

PMID:19402753

LCMS(ID Probability):99.6 MALDI(Z-score):28.523193

Protein

rplL

PMID:19402753

LCMS(ID Probability):99.6

Protein

ParC

PMID:20696938


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

Extracellular

colocalizes with oriC

Fluorescence microscopy

PMID:17824928


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MIERGKFRSL TLINWNGFFA RTFDLDELVT TLSGGNGAGK STTMAAFVTA LIPDLTLLHF
RNTTEAGATS GSRDKGLHGK LKAGVCYSML DTINSRHQRV VVGVRLQQVA GRDRKVDIKP
FAIQGLPMSV QPTQLVTETL NERQARVLPL NELKDKLEAM EGVQFKQFNS ITDYHSLMFD
LGIIARRLRS ASDRSKFYRL IEASLYGGIS SAITRSLRDY LLPENSGVRK AFQDMEAALR
ENRMTLEAIR VTQSDRDLFK HLISEATNYV AADYMRHANE RRVHLDKALE FRRELHTSRQ
QLAAEQYKHV DMARELAEHN GAEGDLEADY QAASDHLNLV QTALRQQEKI ERYEADLDEL
QIRLEEQNEV VAEAIERQQE NEARAEAAEL EVDELKSQLA DYQQALDVQQ TRAIQYNQAI
AALNRAKELC HLPDLTADCA AEWLETFQAK ELEATEKMLS LEQKMSMAQT AHSQFEQAYQ
LVVAINGPLA RNEAWDVARE LLREGVDQRH LAEQVQPLRM RLSELEQRLR EQQEAERLLA
DFCKRQGKNF DIDELEALHQ ELEARIASLS DSVSNAREER MALRQEQEQL QSRIQSLMQR
APVWLAAQNS LNQLSEQCGE EFTSSQDVTE YLQQLLERER EAIVERDEVG ARKNAVDEEI
ERLSQPGGSE DQRLNALAER FGGVLLSEIY DDVSLEDAPY FSALYGPSRH AIVVPDLSQV
TEHLEGLTDC PEDLYLIEGD PQSFDDSVFS VDELEKAVVV KIADRQWRYS RFPEVPLFGR
AARESRIESL HAEREVLSER FATLSFDVQK TQRLHQAFSR FIGSHLAVAF ESDPEAEIRQ
LNSRRVELER ALSNHENDNQ QQRIQFEQAK EGVTALNRIL PRLNLLADDS LADRVDEIRE
RLDEAQEAAR FVQQFGNQLA KLEPIVSVLQ SDPEQFEQLK EDYAYSQQMQ RDARQQAFAL
TEVVQRRAHF SYSDSAEMLS GNSDLNEKLR ERLEQAEAER TRAREALRGH AAQLSQYNQV
LASLKSSYDT KKELLNDLQR ELQDIGVRAD SGAEERARIR RDELHAQLSN NRSRRNQLEK
ALTFCEAEMD NLTRKLRKLE RDYFEMREQV VTAKAGWCAV MRMVKDNGVE RRLHRRELAY
LSADDLRSMS DKALGALRLA VADNEHLRDV LRMSEDPKRP ERKIQFFVAV YQHLRERIRQ
DIIRTDDPVE AIEQMEIELS RLTEELTSRE QKLAISSRSV ANIIRKTIQR EQNRIRMLNQ
GLQNVSFGQV NSVRLNVNVR ETHAMLLDVL SEQHEQHQDL FNSNRLTFSE ALAKLYQRLN
PQIDMGQRTP QTIGEELLDY RNYLEMEVEV NRGSDGWLRA ESGALSTGEA IGTGMSILVM
VVQSWEDESR RLRGKDISPC RLLFLDEAAR LDARSIATLF ELCERLQMQL IIAAPENISP
EKGTTYKLVR KVFQNTEHVH VVGLRGFAPQ LPETLPGTDE APSQAS
Length

1,486

Mol. Wt

170.232 kDa

pI

5.1 (calculated)

Extinction coefficient

90,190 - 91,440 (calc based on 31 Y, 8 W, and 10 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

1..227

PF04310 MukB N-terminal

PMID:19920124

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mukB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128891

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945549

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003138

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P22523

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10618

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10618

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945549

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000611

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0613

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Protein

E. coli K-12 MC4100

3.26E+02

molecules/cell

  • Medium: median data from rich and minimal media
  • Temperature (°C): 37
  • Doubling time (min): Growth Rate(min):
  • Growth phase: other:

emPAI

PMID:18304323

Protein

E.coli MC1000

17,000

molecules/cell

  • Medium: AB minimal medium + 0.2% glycerol + 0.025% Casamino acids + 1µg/ml thiamine
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): Slowly Growing Cells
  • Growth phase: other:

quantitative western

Data Not Shown

PMID:14517265

Protein

E.coli MC1000

40,000

molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): Rapidly Growing Cells
  • Growth phase: other:

quantitative western

Data Not Shown

PMID:14517265

Protein

Ecoli K-12

37.896+/-0.219

Molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): *
  • Growth phase: other: *

Single Molecule Fluorescence

PMID:20671182

mRNA

Ecoli K-12

0.04764574

Molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): *
  • Growth phase: other: *

by RNA_Seq

PMID:20671182

Protein

E. coli K-12 MG1655

1215

molecules/cell/generation

  • Medium: MOPS Complete
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

356

molecules/cell/generation

  • Medium: MOPS Minimal
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

878

molecules/cell/generation

  • Medium: MOPS Complete without Methionine
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

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Notes

Transcription and Transcriptional Regulation

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<protect>

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

smtA-mukFEB

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Figure courtesy of RegulonDB

</protect>

Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000913:975529..975569 source=MG1655 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference
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Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b0924 (EcoliWiki Page)

NCBI GEO profiles for mukB

microarray

GenExpDB:b0924 (EcoliWiki Page)

Summary of data for mukB from multiple microarray studies

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Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes
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Notes

Accessions Related to mukB Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10618

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0613

Escherichia coli str. K-12 substr. MG1655

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b0924

EcoGene

EcoGene:EG10618

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000611

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003138

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Evolution

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{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments

Anopheles gambiae

  • ENSANGP00000026621 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Apis mellifera

  • ENSAPMP00000011739 (score: 1.000; bootstrap: 84%)
  • ENSAPMP00000003169 (score: 0.055)

From Inparanoid:20070104

Arabidopsis thaliana

  • AT5G41790 (score: 1.000; bootstrap: 100%)
  • AT1G64330 (score: 0.144)

From Inparanoid:20070104

Bos taurus

  • ENSBTAP00000021273 (score: 1.000; bootstrap: 51%)
  • ENSBTAP00000015828 (score: 1.000; bootstrap: 51%)
  • ENSBTAP00000028188 (score: 0.701)
  • ENSBTAP00000031792 (score: 0.588)
  • ENSBTAP00000024231 (score: 0.313)
  • ENSBTAP00000009045 (score: 0.311)
  • ENSBTAP00000012800 (score: 0.308)
  • ENSBTAP00000004576 (score: 0.291)
  • ENSBTAP00000024483 (score: 0.234)
  • ENSBTAP00000035330 (score: 0.215)
  • ENSBTAP00000015671 (score: 0.179)
  • ENSBTAP00000012798 (score: 0.170)
  • ENSBTAP00000036284 (score: 0.067)
  • ENSBTAP00000023352 (score: 0.057)
  • ENSBTAP00000011310 (score: 0.056)

From Inparanoid:20070104

Caenorhabditis briggsae

  • WBGene00025170 (score: 1.000; bootstrap: 80%)
  • WBGene00030079 (score: 0.441)
  • WBGene00038900 (score: 0.294)
  • WBGene00041777 (score: 0.294)
  • WBGene00032487 (score: 0.289)
  • WBGene00040581 (score: 0.278)
  • WBGene00023596 (score: 0.271)
  • WBGene00040055 (score: 0.206)
  • WBGene00035391 (score: 0.143)
  • WBGene00038520 (score: 0.101)
  • WBGene00040884 (score: 0.090)
  • WBGene00033338 (score: 0.089)
  • WBGene00034297 (score: 0.088)
  • WBGene00039234 (score: 0.086)

From Inparanoid:20070104

Caenorhabditis elegans

  • WBGene00003776 (score: 1.000; bootstrap: 100%)
  • WBGene00010306 (score: 1.000; bootstrap: 100%)
  • WBGene00003777 (score: 0.460)
  • WBGene00019064 (score: 0.301)
  • WBGene00003515 (score: 0.298)
  • WBGene00006789 (score: 0.296)
  • WBGene00002348 (score: 0.276)
  • WBGene00003514 (score: 0.271)
  • WBGene00009730 (score: 0.204)
  • WBGene00012437 (score: 0.141)
  • WBGene00002036 (score: 0.103)
  • WBGene00004969 (score: 0.090)
  • WBGene00002035 (score: 0.086)
  • WBGene00002041 (score: 0.086)
  • WBGene00002038 (score: 0.086)
  • WBGene00001829 (score: 0.057)

From Inparanoid:20070104

Canis familiaris

  • ENSCAFP00000002078 (score: 1.000; bootstrap: 66%)
  • ENSCAFP00000004692 (score: 0.148)

From Inparanoid:20070104

Ciona intestinalis

  • ENSCINP00000019679 (score: 1.000; bootstrap: 81%)

From Inparanoid:20070104

Danio rerio

  • ZDB-GENE-050531-1 (score: 1.000; bootstrap: 70%)
  • ZDB-GENE-030131-5870 (score: 0.406)
  • ZDB-GENE-991123-5 (score: 0.354)
  • ZDB-GENE-030131-271 (score: 0.353)
  • ZDB-CDNA-040625-75 (score: 0.345)
  • ZDB-GENE-020604-1 (score: 0.345)
  • ZDB-GENE-031112-1 (score: 0.344)
  • ZDB-GENE-030131-6206 (score: 0.344)
  • ZDB-GENE-040426-1554 (score: 0.301)
  • ZDB-GENE-050913-143 (score: 0.137)
  • ZDB-CDNA-040425-2488 (score: 0.113)
  • ZDB-GENE-030318-3 (score: 0.099)
  • ZDB-GENE-040819-2 (score: 0.096)
  • ZDB-GENE-041026-4 (score: 0.093)
  • ZDB-CDNA-040425-2281 (score: 0.089)
  • ZDB-GENE-040426-1347 (score: 0.089)
  • ZDB-GENE-050327-46 (score: 0.080)

From Inparanoid:20070104

Dictyostelium discoideum

  • DDB0188916 (score: 1.000; bootstrap: 100%)
  • DDB0191136 (score: 0.101)
  • DDB0216970 (score: 0.098)
  • DDB0191988 (score: 0.062)
  • DDB0191404 (score: 0.061)
  • DDB0191488 (score: 0.057)
  • DDB0187764 (score: 0.055)
  • DDB0202870 (score: 0.053)

From Inparanoid:20070104

Drosophila melanogaster

  • FBgn0020503 (score: 1.000; bootstrap: 66%)

From Inparanoid:20070104

Drosophila pseudoobscura

  • GA13959-PA (score: 1.000; bootstrap: 76%)
  • GA15963-PA (score: 0.106)
  • GA15267-PA (score: 0.102)
  • GA21581-PA (score: 0.091)
  • GA19246-PA (score: 0.067)

From Inparanoid:20070104

Gallus gallus

  • ENSGALP00000018382 (score: 1.000; bootstrap: 78%)
  • ENSGALP00000019146 (score: 0.051)

From Inparanoid:20070104

Homo sapiens

  • ENSP00000323856 (score: 1.000; bootstrap: 100%)
  • ENSP00000307959 (score: 0.147)
  • ENSP00000301607 (score: 0.058)

From Inparanoid:20070104

Macaca mulatta

  • ENSMMUP00000000518 (score: 1.000; bootstrap: 71%)
  • ENSMMUP00000019406 (score: 0.179)
  • ENSMMUP00000001063 (score: 0.146)

From Inparanoid:20070104

Monodelphis domestica

  • ENSMODP00000005379 (score: 1.000; bootstrap: 73%)
  • ENSMODP00000001289 (score: 0.773)
  • ENSMODP00000010173 (score: 0.762)
  • ENSMODP00000001542 (score: 0.361)
  • ENSMODP00000005333 (score: 0.359)
  • ENSMODP00000000577 (score: 0.356)
  • ENSMODP00000001685 (score: 0.354)
  • ENSMODP00000005446 (score: 0.354)
  • ENSMODP00000001777 (score: 0.338)
  • ENSMODP00000004596 (score: 0.130)
  • ENSMODP00000002283 (score: 0.130)
  • ENSMODP00000002338 (score: 0.115)
  • ENSMODP00000024115 (score: 0.107)
  • ENSMODP00000014825 (score: 0.098)
  • ENSMODP00000023052 (score: 0.095)
  • ENSMODP00000011071 (score: 0.095)
  • ENSMODP00000004415 (score: 0.089)
  • ENSMODP00000012931 (score: 0.088)
  • ENSMODP00000023935 (score: 0.086)
  • ENSMODP00000003118 (score: 0.085)
  • ENSMODP00000010443 (score: 0.082)
  • ENSMODP00000010819 (score: 0.081)
  • ENSMODP00000022529 (score: 0.079)
  • ENSMODP00000023281 (score: 0.075)
  • ENSMODP00000017896 (score: 0.074)
  • ENSMODP00000018798 (score: 0.072)
  • ENSMODP00000004125 (score: 0.071)
  • ENSMODP00000005694 (score: 0.057)

From Inparanoid:20070104

Mus musculus

  • MGI:105313 (score: 1.000; bootstrap: 70%)
  • MGI:107927 (score: 0.082)
  • MGI:107926 (score: 0.080)
  • MGI:2136459 (score: 0.076)
  • MGI:2652845 (score: 0.073)
  • MGI:94906 (score: 0.055)
  • MGI:2441841 (score: 0.054)

From Inparanoid:20070104

Oryza gramene

  • Q7XEH4 (score: 1.000; bootstrap: 100%)
  • Q75J40 (score: 0.105)

From Inparanoid:20070104

Pan troglodytes

  • ENSPTRP00000035355 (score: 1.000; bootstrap: 84%)
  • ENSPTRP00000030221 (score: 0.163)
  • ENSPTRP00000000995 (score: 0.090)

From Inparanoid:20070104

Rattus norvegicus

  • ENSRNOP00000003983 (score: 1.000; bootstrap: 60%)
  • ENSRNOP00000007398 (score: 0.778)
  • ENSRNOP00000047484 (score: 0.736)
  • ENSRNOP00000027132 (score: 0.663)
  • ENSRNOP00000024186 (score: 0.354)
  • ENSRNOP00000004147 (score: 0.353)
  • ENSRNOP00000023301 (score: 0.349)
  • ENSRNOP00000025859 (score: 0.341)
  • ENSRNOP00000004236 (score: 0.303)
  • ENSRNOP00000042194 (score: 0.292)
  • ENSRNOP00000045110 (score: 0.211)
  • ENSRNOP00000004295 (score: 0.189)
  • ENSRNOP00000046362 (score: 0.174)
  • ENSRNOP00000019512 (score: 0.135)
  • ENSRNOP00000029604 (score: 0.131)
  • ENSRNOP00000043034 (score: 0.129)
  • ENSRNOP00000011199 (score: 0.114)
  • ENSRNOP00000019053 (score: 0.108)
  • ENSRNOP00000048088 (score: 0.098)
  • ENSRNOP00000016428 (score: 0.098)
  • ENSRNOP00000015963 (score: 0.095)
  • ENSRNOP00000004609 (score: 0.092)
  • ENSRNOP00000028929 (score: 0.092)
  • ENSRNOP00000011513 (score: 0.091)
  • ENSRNOP00000016696 (score: 0.088)
  • ENSRNOP00000010021 (score: 0.085)
  • ENSRNOP00000025053 (score: 0.081)

From Inparanoid:20070104

Saccharomyces cerevisiae

  • YDL058W (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Schizosaccharomyces pombe

  • SPAC1F36c (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Takifugu rubripes

  • NEWSINFRUP00000143030 (score: 1.000; bootstrap: 100%)
  • NEWSINFRUP00000145741 (score: 0.058)

From Inparanoid:20070104

Tetraodon nigroviridis

  • GSTENP00004944001 (score: 1.000; bootstrap: 59%)

From Inparanoid:20070104

Xenopus tropicalis

  • ENSXETP00000042559 (score: 1.000; bootstrap: 56%)
  • ENSXETP00000000485 (score: 0.738)
  • ENSXETP00000035703 (score: 0.721)
  • ENSXETP00000041404 (score: 0.691)
  • ENSXETP00000038638 (score: 0.357)
  • ENSXETP00000035470 (score: 0.355)
  • ENSXETP00000035510 (score: 0.354)
  • ENSXETP00000026213 (score: 0.353)
  • ENSXETP00000035199 (score: 0.352)
  • ENSXETP00000035539 (score: 0.351)
  • ENSXETP00000051645 (score: 0.349)
  • ENSXETP00000051662 (score: 0.342)
  • ENSXETP00000035586 (score: 0.334)
  • ENSXETP00000016274 (score: 0.309)
  • ENSXETP00000031913 (score: 0.289)
  • ENSXETP00000043854 (score: 0.129)
  • ENSXETP00000044821 (score: 0.124)
  • ENSXETP00000020845 (score: 0.122)
  • ENSXETP00000044808 (score: 0.108)
  • ENSXETP00000007787 (score: 0.103)
  • ENSXETP00000023437 (score: 0.101)
  • ENSXETP00000009634 (score: 0.092)
  • ENSXETP00000049495 (score: 0.091)
  • ENSXETP00000035798 (score: 0.091)
  • ENSXETP00000003172 (score: 0.090)
  • ENSXETP00000006960 (score: 0.089)
  • ENSXETP00000040215 (score: 0.087)
  • ENSXETP00000020998 (score: 0.087)
  • ENSXETP00000035603 (score: 0.080)
  • ENSXETP00000040866 (score: 0.078)
  • ENSXETP00000040542 (score: 0.077)
  • ENSXETP00000046397 (score: 0.064)
  • ENSXETP00000044780 (score: 0.062)

From Inparanoid:20070104

Shigella flexneri

MUKB

From SHIGELLACYC

E. coli O157

MUKB

From ECOO157CYC

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Do-It-Yourself Web Tools

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Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

Pfam (EcoliWiki Page)

PF04310 MukB N-terminal

Superfamily (EcoliWiki Page)

SUPERFAMILY:52540

Panther (EcoliWiki Page)

PTHR18937:SF146

EcoCyc

EcoCyc:EG10618

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10618

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000611

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0613

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003138

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Niki, H et al. (1991) The new gene mukB codes for a 177 kd protein with coiled-coil domains involved in chromosome partitioning of E. coli. EMBO J. 10 183-93 PubMed
  6. ↑ 6.0 6.1 CGSC: The Coli Genetics Stock Center
  7. ↑ 7.0 7.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).

Categories

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