metK:On One Page

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

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Standard Name

metK

Gene Synonym(s)

ECK2937, b2942, JW2909, metX[1], metX

Product Desc.

MetK S-adenosylmethionine synthetase[2][3];

Component of methionine adenosyltransferase I[2][3]

S-adenosylmethionine synthase; methionine adenosyltransferase; ethionine sensitivity; essential gene[4]

Product Synonyms(s)

methionine adenosyltransferase 1[1], B2942[2][1], MetX[2][1], MetK[2][1] , ECK2937, JW2909, metX, b2942

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): metK[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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The adjacent ORF yqgD has been removed from EcoGene because it is very unlikely to be a gene; the limited conservation with Salmonella is apparently due to a pseudotranslation of the conserved metK CRP site, promoter and the metK 5' UTR.[4]



Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

metK

Mnemonic

Methionine

Synonyms

ECK2937, b2942, JW2909, metX[1], metX

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

66.49 minutes 

MG1655: 3084728..3085882
<gbrowseImage> name=NC_000913:3084728..3085882 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 2972457..2973611
<gbrowseImage> name=NC_012967:2972457..2973611 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 2971876..2973030
<gbrowseImage> name=NC_012759:2971876..2973030 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 3085362..3086516
<gbrowseImage> name=NC_007779:3085362..3086516 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 3179797..3180951
<gbrowseImage> name=NC_010473:3179797..3180951 source=DH10B preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

Coding Start (SO:0000323)

MG1655

3084731

Edman degradation

PMID:9579078


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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

metKD239N

D239N

Decrease in AdoMet synthesis

seeded from UniProt:P0A817

metKK246M

K246M

Loss of activity. modification in protein conformation

seeded from UniProt:P0A817

metKK266A

K266A

Loss of activity

seeded from UniProt:P0A817

metKK266M

K266M

Unstable; trace activity

seeded from UniProt:P0A817

metKK270M

K270M

Decrease in activity

seeded from UniProt:P0A817

metKD272N,A

D272N,A

Loss of activity

seeded from UniProt:P0A817

metKC240A

C240A

Decrease in AdoMet synthesis

seeded from UniProt:P0A817

metKR245H,L

R245H,L

Loss of activity

seeded from UniProt:P0A817

metKK166M

K166M

Decrease in AdoMet synthesis

seeded from UniProt:P0A817

metKD119N

D119N

Decrease of both AdoMet synthesis and AdoMet-activated tripolyphosphate hydrolysis

seeded from UniProt:P0A817

metKH15N

H15N

Loss of activity

seeded from UniProt:P0A817

metKD17N,A

D17N,A

Loss of activity

seeded from UniProt:P0A817

metKE43K

E43K

Misfolding and subject to proteolytic degradation

seeded from UniProt:P0A817

metKE43Q

E43Q

Loss of stimulation by potassium

seeded from UniProt:P0A817

metKC90A,S

C90A,S

Decrease in the homotetramer formation capability. Enhanced thermal stability

seeded from UniProt:P0A817

metK86

Resistant to

ethionine resistant

PMID:4577753

CGSC:11765

isolation described in materials and methods

parent strain: wild-type E. coli K-12 from S. Gross at Duke University

metK110(ts)

temperature sensitive

CGSC:9147


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Notes

Genetic Interactions

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<protect>

Interactor Interaction Allele Score(s) Reference(s) Accessions Notes
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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW2909

Plasmid clone

Shigen

PMID:16769691

Status:Clone OK

Primer 1:GCCGCAAAACACCTTTTTACGTC

Primer 2:CCtTTCAGACCGGCAGCATCGCG

1H10

Kohara Phage

Genobase

PMID:3038334

23G4S

Kohara Phage

Genobase

PMID:3038334

recD1901::Tn10

Linked marker

CAG12135 = CGSC7429[5]

est. P1 cotransduction: % [6]

speA210::Tn10

Linked marker

CAG12168 = CGSC7431[5]

est. P1 cotransduction: 98% [6]
Synonyms:zgd-210::Tn10, zgf-210::Tn10

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10589

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10589

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000582

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:945389

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0584

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0009650

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MetK

Synonyms

methionine adenosyltransferase 1[1], B2942[2][1], MetX[2][1], MetK[2][1] , ECK2937, JW2909, metX, b2942

Product description

MetK S-adenosylmethionine synthetase[2][3];

Component of methionine adenosyltransferase I[2][3]

S-adenosylmethionine synthase; methionine adenosyltransferase; ethionine sensitivity; essential gene[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0000287

magnesium ion binding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00086

F

Seeded from EcoCyc (v14.0)

complete

GO:0000287

magnesium ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0460

F

Seeded from EcoCyc (v14.0)

complete

GO:0004478

methionine adenosyltransferase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00086

F

Seeded from EcoCyc (v14.0)

complete

GO:0004478

methionine adenosyltransferase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002133

F

Seeded from EcoCyc (v14.0)

complete

GO:0004478

methionine adenosyltransferase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.5.1.6

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00086

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002133

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005829

cytosol

PMID:16858726

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0030955

potassium ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0630

F

Seeded from EcoCyc (v14.0)

complete

GO:0050897

cobalt ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0170

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of methionine adenosyltransferase I

could be indirect

Protein

fdnH

PMID:16606699

Experiment(s):EBI-1144372

Protein

prs

PMID:16606699

Experiment(s):EBI-1144372

Protein

ybfC

PMID:16606699

Experiment(s):EBI-1144372

Protein

groL

PMID:16606699

Experiment(s):EBI-1144372

Protein

nadE

PMID:16606699

Experiment(s):EBI-1144372

Protein

phnN

PMID:16606699

Experiment(s):EBI-1144372

Protein

speB

PMID:16606699

Experiment(s):EBI-1144372

Protein

degQ

PMID:16606699

Experiment(s):EBI-1144372

Protein

dnaK

PMID:15690043

Experiment(s):EBI-881611

Protein

glyQ

PMID:15690043

Experiment(s):EBI-881611

Protein

mreB

PMID:15690043

Experiment(s):EBI-881611

Protein

pstB

PMID:15690043

Experiment(s):EBI-881611

Protein

recA

PMID:15690043

Experiment(s):EBI-881611

Protein

secA

PMID:15690043

Experiment(s):EBI-881611, EBI-880477

Protein

tufA

PMID:15690043

Experiment(s):EBI-881611, EBI-889981, EBI-889076

Protein

recA

PMID:19402753

MALDI(Z-score):28.691364

Protein

pstB

PMID:19402753

MALDI(Z-score):31.949994

Protein

dnaJ

PMID:19402753

LCMS(ID Probability):99.6 MALDI(Z-score):37.245489

Protein

mreB

PMID:19402753

MALDI(Z-score):34.359287

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MAKHLFTSES VSEGHPDKIA DQISDAVLDA ILEQDPKARV ACETYVKTGM VLVGGEITTS
AWVDIEEITR NTVREIGYVH SDMGFDANSC AVLSAIGKQS PDINQGVDRA DPLEQGAGDQ
GLMFGYATNE TDVLMPAPIT YAHRLVQRQA EVRKNGTLPW LRPDAKSQVT FQYDDGKIVG
IDAVVLSTQH SEEIDQKSLQ EAVMEEIIKP ILPAEWLTSA TKFFINPTGR FVIGGPMGDC
GLTGRKIIVD TYGGMARHGG GAFSGKDPSK VDRSAAYAAR YVAKNIVAAG LADRCEIQVS
YAIGVAEPTS IMVETFGTEK VPSEQLTLLV REFFDLRPYG LIQMLDLLHP IYKETAAYGH
FGREHFPWEK TDKAQLLRDA AGLK
Length

384

Mol. Wt

41.951 kDa

pI

5.0 (calculated)

Extinction coefficient

39,880 - 40,380 (calc based on 12 Y, 4 W, and 4 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P0A817

Modification Site

198

phosphorylation site at S198

probability greater than 75%

PMID:17938405

Domain

2..101

PF00438 S-adenosylmethionine synthetase, N-terminal domain

PMID:19920124

Domain

113..231

PF02772 S-adenosylmethionine synthetase, central domain

PMID:19920124

Domain

233..370

PF02773 S-adenosylmethionine synthetase, C-terminal domain

PMID:19920124

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=metK taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130843

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945389

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0009650

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A817

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10589

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10589

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945389

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000582

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0584

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Protein

E. coli K-12 MC4100

1.89E+03

molecules/cell

  • Medium: median data from rich and minimal media
  • Temperature (°C): 37
  • Doubling time (min): Growth Rate(min):
  • Growth phase: other:

emPAI

PMID:18304323

Protein

Ecoli K-12

347.042+/-2.124

Molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): *
  • Growth phase: other: *

Single Molecule Fluorescence

PMID:20671182

mRNA

Ecoli K-12

0.5837+/-0.01466

Molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): *
  • Growth phase: other: *

by FISH

PMID:20671182

mRNA

Ecoli K-12

0.147313692

Molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): *
  • Growth phase: other: *

by RNA_Seq

PMID:20671182

Protein

E. coli K-12 MG1655

22856

molecules/cell/generation

  • Medium: MOPS Complete
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

7214

molecules/cell/generation

  • Medium: MOPS Minimal
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

26255

molecules/cell/generation

  • Medium: MOPS Complete without Methionine
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

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Notes

Transcription and Transcriptional Regulation

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<protect>

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

metK

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Figure courtesy of RegulonDB

</protect>

Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000913:3084708..3084748 source=MG1655 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

</protect>

Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference
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Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b2942 (EcoliWiki Page)

NCBI GEO profiles for metK

microarray

GenExpDB:b2942 (EcoliWiki Page)

Summary of data for metK from multiple microarray studies

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Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes

GFP Fusion

Intergenic region (3084581..3084751) fused to gfpmut2.

OpenBioSystems

GFP fusion described in Zaslaver, et al.
Plate:109-AZ05; Well:E7[7]

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Notes

Accessions Related to metK Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10589

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0584

Escherichia coli str. K-12 substr. MG1655

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b2942

EcoGene

EcoGene:EG10589

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000582

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0009650

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments

Anopheles gambiae

  • ENSANGP00000023437 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Apis mellifera

  • ENSAPMP00000033210 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Arabidopsis thaliana

  • AT2G36880 (score: 1.000; bootstrap: 100%)
  • AT3G17390 (score: 1.000; bootstrap: 100%)
  • AT1G02500 (score: 0.848)
  • AT4G01850 (score: 0.845)

From Inparanoid:20070104

Bos taurus

  • ENSBTAP00000031255 (score: 1.000; bootstrap: 100%)
  • ENSBTAP00000027808 (score: 0.617)

From Inparanoid:20070104

Caenorhabditis briggsae

  • WBGene00038995 (score: 1.000; bootstrap: 100%)
  • WBGene00038996 (score: 0.861)
  • WBGene00035751 (score: 0.520)

From Inparanoid:20070104

Caenorhabditis elegans

  • WBGene00015540 (score: 1.000; bootstrap: 100%)
  • WBGene00015538 (score: 0.865)
  • WBGene00006416 (score: 0.843)
  • WBGene00013652 (score: 0.610)
  • WBGene00008205 (score: 0.585)

From Inparanoid:20070104

Canis familiaris

  • ENSCAFP00000011509 (score: 1.000; bootstrap: 100%)
  • ENSCAFP00000023298 (score: 0.725)

From Inparanoid:20070104

Ciona intestinalis

  • ENSCINP00000016721 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Danio rerio

  • ZDB-GENE-030131-6127 (score: 1.000; bootstrap: 100%)
  • ZDB-CDNA-040425-505 (score: 1.000; bootstrap: 100%)
  • ZDB-CDNA-050327-6 (score: 0.547)
  • ZDB-GENE-050327-6 (score: 0.547)
  • ZDB-CDNA-040425-506 (score: 0.169)
  • ZDB-GENE-030131-2049 (score: 0.169)

From Inparanoid:20070104

Dictyostelium discoideum

  • DDB0230070 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Drosophila melanogaster

  • FBgn0005278 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Drosophila pseudoobscura

  • GA15421-PA (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Gallus gallus

  • ENSGALP00000003899 (score: 1.000; bootstrap: 100%)
  • ENSGALP00000024750 (score: 0.426)

From Inparanoid:20070104

Homo sapiens

  • ENSP00000303147 (score: 1.000; bootstrap: 100%)
  • ENSP00000280867 (score: 0.732)

From Inparanoid:20070104

Macaca mulatta

  • ENSMMUP00000024512 (score: 1.000; bootstrap: 100%)
  • ENSMMUP00000005930 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Monodelphis domestica

  • ENSMODP00000019473 (score: 1.000; bootstrap: 100%)
  • ENSMODP00000001856 (score: 0.683)

From Inparanoid:20070104

Mus musculus

  • MGI:88017 (score: 1.000; bootstrap: 100%)
  • MGI:2443731 (score: 0.708)

From Inparanoid:20070104

Oryza gramene

  • Q4LB21 (score: 1.000; bootstrap: 100%)
  • Q9LGU6 (score: 0.906)
  • Q6AVZ2 (score: 0.897)
  • P46611 (score: 0.897)
  • Q8VXC5 (score: 0.894)
  • Q7F660 (score: 0.835)
  • P93438 (score: 0.835)
  • Q4LB24 (score: 0.818)
  • Q4LB23 (score: 0.815)
  • P50299 (score: 0.813)
  • Q4LB22 (score: 0.793)
  • Q8W531 (score: 0.207)

From Inparanoid:20070104

Pan troglodytes

  • ENSPTRP00000004677 (score: 1.000; bootstrap: 100%)
  • ENSPTRP00000020814 (score: 0.055)

From Inparanoid:20070104

Rattus norvegicus

  • ENSRNOP00000018170 (score: 1.000; bootstrap: 100%)
  • ENSRNOP00000015190 (score: 0.384)

From Inparanoid:20070104

Saccharomyces cerevisiae

  • YDR502C (score: 1.000; bootstrap: 100%)
  • YLR180W (score: 0.842)

From Inparanoid:20070104

Schizosaccharomyces pombe

  • SPBC14F55c (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Takifugu rubripes

  • NEWSINFRUP00000150744 (score: 1.000; bootstrap: 100%)
  • NEWSINFRUP00000165612 (score: 0.661)
  • NEWSINFRUP00000165342 (score: 0.400)
  • NEWSINFRUP00000160504 (score: 0.365)
  • NEWSINFRUP00000136500 (score: 0.229)

From Inparanoid:20070104

Tetraodon nigroviridis

  • GSTENP00016485001 (score: 1.000; bootstrap: 100%)
  • GSTENP00017321001 (score: 0.656)
  • GSTENP00029452001 (score: 0.603)
  • GSTENP00022288001 (score: 0.372)
  • GSTENP00025261001 (score: 0.242)

From Inparanoid:20070104

Xenopus tropicalis

  • ENSXETP00000007635 (score: 1.000; bootstrap: 100%)
  • ENSXETP00000002716 (score: 0.510)

From Inparanoid:20070104

Shigella flexneri

METK

From SHIGELLACYC

E. coli O157

METK

From ECOO157CYC

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Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

Panther (EcoliWiki Page)

PTHR11964:SF0

Superfamily (EcoliWiki Page)

SUPERFAMILY:55973

Superfamily (EcoliWiki Page)

SUPERFAMILY:55973

Superfamily (EcoliWiki Page)

SUPERFAMILY:55973

Pfam (EcoliWiki Page)

PF00438 S-adenosylmethionine synthetase, N-terminal domain

Pfam (EcoliWiki Page)

PF02772 S-adenosylmethionine synthetase, central domain

Pfam (EcoliWiki Page)

PF02773 S-adenosylmethionine synthetase, C-terminal domain

EcoCyc

EcoCyc:EG10589

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10589

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000582

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0584

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0009650

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 CGSC: The Coli Genetics Stock Center
  6. ↑ 6.0 6.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
  7. ↑ Zaslaver, A et al. (2006) A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Nat. Methods 3 623-8 PubMed

Categories

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