parC:Gene Product(s): Difference between revisions
Data loaded by TableEdit_Loader. |
DanielRenfro (talk | contribs) Table edited by DanielRenfro via TableEdit |
||
| Line 83: | Line 83: | ||
| | | | ||
GO:0003677 | |||
| | | | ||
DNA binding | DNA binding | ||
| | | | ||
GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR006691<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760<br />SP_KW:KW-0238 | |||
| | | | ||
F | F | ||
| Line 102: | Line 102: | ||
| | | | ||
GO:0003916 | |||
| | | | ||
DNA topoisomerase activity | DNA topoisomerase activity | ||
| | | | ||
GO_REF:0000002<br />GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR006691<br />SP_KW:KW-0799 | |||
| | | | ||
F | F | ||
| Line 121: | Line 121: | ||
| | | | ||
GO:0003918 | |||
| | | | ||
DNA topoisomerase (ATP-hydrolyzing) activity | DNA topoisomerase (ATP-hydrolyzing) activity | ||
| | | | ||
GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760 | |||
| | | | ||
F | F | ||
| Line 140: | Line 140: | ||
| | | | ||
GO:0005524 | |||
| | | | ||
ATP binding | ATP binding | ||
| | | | ||
GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR006691<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760 | |||
| | | | ||
F | F | ||
| Line 159: | Line 159: | ||
| | | | ||
GO:0005694 | |||
| | | | ||
chromosome | chromosome | ||
| | | | ||
GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR006691<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760 | |||
| | | | ||
C | C | ||
| Line 178: | Line 178: | ||
| | | | ||
GO:0006265 | |||
| | | | ||
DNA topological change | DNA topological change | ||
| | | | ||
GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR006691<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760 | |||
| | | | ||
P | P | ||
| Line 197: | Line 197: | ||
| | | | ||
GO:0006268 | |||
| | | | ||
DNA unwinding during replication | DNA unwinding during replication | ||
| | | | ||
GO_REF:0000002<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR005742<br />InterPro:IPR006691 | |||
| | | | ||
P | P | ||
| Line 216: | Line 216: | ||
| | | | ||
GO:0016020 | |||
| | | | ||
membrane | membrane | ||
| | | | ||
GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW-0472 | |||
| | | | ||
C | C | ||
| Line 235: | Line 235: | ||
| | | | ||
GO:0016853 | |||
| | | | ||
isomerase activity | isomerase activity | ||
| | | | ||
GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW-0413 | |||
| | | | ||
F | F | ||
| Line 254: | Line 254: | ||
| | | | ||
GO:0005737 | |||
| | | | ||
cytoplasm | cytoplasm | ||
| | | | ||
PMID:12535532 | |||
| | | | ||
IDA: Inferred from Direct Assay | IDA: Inferred from Direct Assay | ||
| Line 272: | Line 273: | ||
| | | | ||
GO:0006261 | |||
| | | | ||
DNA-dependent DNA replication | DNA-dependent DNA replication | ||
| | | | ||
PMID:2170028 | |||
| | | | ||
IDA: Inferred from Direct Assay | IDA: Inferred from Direct Assay | ||
| Line 290: | Line 292: | ||
| | | | ||
GO:0003918 | |||
| | | | ||
DNA topoisomerase (ATP-hydrolyzing) activity | DNA topoisomerase (ATP-hydrolyzing) activity | ||
| Line 309: | Line 311: | ||
| | | | ||
GO:0007059 | |||
| | | | ||
chromosome segregation | chromosome segregation | ||
| | | | ||
PMID:2842295 | |||
| | | | ||
IMP: Inferred from Mutant Phenotype | IMP: Inferred from Mutant Phenotype | ||
| Line 327: | Line 330: | ||
Contributes to | Contributes to | ||
| | | | ||
GO:0003916 | |||
| | | | ||
DNA topoisomerase activity | DNA topoisomerase activity | ||
| | | | ||
PMID:1334483 | |||
| | | | ||
IDA: Inferred from Direct Assay | IDA: Inferred from Direct Assay | ||
| Line 345: | Line 349: | ||
| | | | ||
GO:0019897 | |||
| | | | ||
extrinsic to plasma membrane | extrinsic to plasma membrane | ||
| | | | ||
PMID:1334483 | |||
| | | | ||
IDA: Inferred from Direct Assay | IDA: Inferred from Direct Assay | ||
| Line 363: | Line 368: | ||
| | | | ||
GO:0005737 | |||
| | | | ||
cytoplasm | cytoplasm | ||
| | | | ||
PMID:1334483 | |||
| | | | ||
IDA: Inferred from Direct Assay | IDA: Inferred from Direct Assay | ||
| Line 381: | Line 387: | ||
Contributes to | Contributes to | ||
| | | | ||
GO:0003918 | |||
| | | | ||
DNA topoisomerase (ATP-hydrolyzing) activity | DNA topoisomerase (ATP-hydrolyzing) activity | ||
| | | | ||
PMID:8227000 | |||
| | | | ||
IDA: Inferred from Direct Assay | IDA: Inferred from Direct Assay | ||
| Line 399: | Line 406: | ||
| | | | ||
GO:0009330 | |||
| | | | ||
DNA topoisomerase complex (ATP-hydrolyzing) | DNA topoisomerase complex (ATP-hydrolyzing) | ||
| | | | ||
PMID:8227000 | |||
| | | | ||
IDA: Inferred from Direct Assay | IDA: Inferred from Direct Assay | ||
| Line 417: | Line 425: | ||
| | | | ||
GO:0006265 | |||
| | | | ||
DNA topological change | DNA topological change | ||
| | | | ||
PMID:8227000 | |||
| | | | ||
IDA: Inferred from Direct Assay | IDA: Inferred from Direct Assay | ||
| Line 435: | Line 444: | ||
| | | | ||
GO:0003677 | |||
| | | | ||
DNA binding | DNA binding | ||
| | | | ||
PMID:18023670 | |||
| | | | ||
IDA: Inferred from Direct Assay | IDA: Inferred from Direct Assay | ||
| Line 453: | Line 463: | ||
| | | | ||
GO:0030541 | |||
| | | | ||
plasmid partitioning | plasmid partitioning | ||
| | | | ||
PMID:8104339 | |||
| | | | ||
Revision as of 16:35, 16 February 2009
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
ParC |
|---|---|
| Synonyms | |
| Product description |
topoisomerase IV subunit A[2][3]; Component of dimer of topoisomerase IV subunit A[3]; topoisomerase IV[3] |
| EC number (for enzymes) | |
| edit table |
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002205 |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |
| GO:0003916 |
DNA topoisomerase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0003918 |
DNA topoisomerase (ATP-hydrolyzing) activity |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002205 |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |
| GO:0005524 |
ATP binding |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002205 |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |
| GO:0005694 |
chromosome |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002205 |
C |
Seeded from EcoCyc 12.5 [4] |
complete | |
| GO:0006265 |
DNA topological change |
GO_REF:0000002 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002205 |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |
| GO:0006268 |
DNA unwinding during replication |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0016853 |
isomerase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc 11.1[3]. |
complete | |||
| GO:0006261 |
DNA-dependent DNA replication |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc 11.1[3]. |
complete | |||
| GO:0003918 |
DNA topoisomerase (ATP-hydrolyzing) activity |
IDA: Inferred from Direct Assay |
F |
required field missing | ||||
| GO:0007059 |
chromosome segregation |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
|
Contributes to |
GO:0003916 |
DNA topoisomerase activity |
IDA: Inferred from Direct Assay |
F |
complete | |||
| GO:0019897 |
extrinsic to plasma membrane |
IDA: Inferred from Direct Assay |
C |
in the presence of DNA |
complete | |||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
in the presence of Mg2+ |
complete | |||
|
Contributes to |
GO:0003918 |
DNA topoisomerase (ATP-hydrolyzing) activity |
IDA: Inferred from Direct Assay |
F |
complete | |||
| GO:0009330 |
DNA topoisomerase complex (ATP-hydrolyzing) |
IDA: Inferred from Direct Assay |
C |
complete | ||||
| GO:0006265 |
DNA topological change |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0003677 |
DNA binding |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0030541 |
plasmid partitioning |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
could be indirect |
|||
|
Protein |
PMID:16606699[12] |
Experiment(s):EBI-1144556 | ||
|
Protein |
PMID:16606699[12] |
Experiment(s):EBI-1144556 | ||
|
Protein |
PMID:16606699[12] |
Experiment(s):EBI-1144556 | ||
|
Protein |
PMID:16606699[12] |
Experiment(s):EBI-1144556 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-883350 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-883350 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-883350 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-883350 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-883350 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
|
Protein |
Subunits of topoisomerase IV |
could be indirect |
||
|
Protein |
PMID:15690043[13] |
Experiment(s):EBI-890645 | ||
| edit table |
See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
|
cytoplasm |
From EcoCyc[3] | ||
| edit table |
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MSDMAERLAL HEFTENAYLN YSMYVIMDRA LPFIGDGLKP VQRRIVYAMS ELGLNASAKF KKSARTVGDV LGKYHPHGDS ACYEAMVLMA QPFSYRYPLV DGQGNWGAPD DPKSFAAMRY TESRLSKYSE LLLSELGQGT ADWVPNFDGT LQEPKMLPAR LPNILLNGTT GIAVGMATDI PPHNLREVAQ AAIALIDQPK TTLDQLLDIV QGPDYPTEAE IITSRAEIRK IYENGRGSVR MRAVWKKEDG AVVISALPHQ VSGARVLEQI AAQMRNKKLP MVDDLRDESD HENPTRLVIV PRSNRVDMDQ VMNHLFATTD LEKSYRINLN MIGLDGRPAV KNLLEILSEW LVFRRDTVRR RLNYRLEKVL KRLHILEGLL VAFLNIDEVI EIIRNEDEPK PALMSRFGLT ETQAEAILEL KLRHLAKLEE MKIRGEQSEL EKERDQLQGI LASERKMNNL LKKELQADAQ AYGDDRRSPL QEREEAKAMS EHDMLPSEPV TIVLSQMGWV RSAKGHDIDA PGLNYKAGDS FKAAVKGKSN QPVVFVDSTG RSYAIDPITL PSARGQGEPL TGKLTLPPGA TVDHMLMESD DQKLLMASDA GYGFVCTFND LVARNRAGKA LITLPENAHV MPPVVIEDAS DMLLAITQAG RMLMFPVSDL PQLSKGKGNK IINIPSAEAA RGEDGLAQLY VLPPQSTLTI HVGKRKIKLR PEELQKVTGE RGRRGTLMRG LQRIDRVEID SPRRASSGDS EE |
|---|---|
| Mol. Wt |
83.83 kDa (calc) [2] |
| pI | |
| Extinction coefficient |
55810 - 56060 (calc based on 19 Y, 5 W, and 2 C residues) |
| edit table |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
| Type | Residues | Description | Notes |
|---|---|---|---|
| edit table |
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
| Structures |
<beststructure>parC 562</beststructure> |
|---|---|
| Models |
View models at: |
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Espeli, O et al. (2003) Temporal regulation of topoisomerase IV activity in E. coli. Mol. Cell 11 189-201 PubMed
- ↑ Kato, J et al. (1990) New topoisomerase essential for chromosome segregation in E. coli. Cell 63 393-404 PubMed
- ↑ Kato, J et al. (1988) Gene organization in the region containing a new gene involved in chromosome partition in Escherichia coli. J. Bacteriol. 170 3967-77 PubMed
- ↑ 8.0 8.1 8.2 Kato, J et al. (1992) Purification and characterization of DNA topoisomerase IV in Escherichia coli. J. Biol. Chem. 267 25676-84 PubMed
- ↑ 9.0 9.1 9.2 Peng, H & Marians, KJ (1993) Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions. J. Biol. Chem. 268 24481-90 PubMed
- ↑ Nakajima, T et al. (2007) The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors. J Thorac Cardiovasc Surg 134 1485-90 PubMed
- ↑ Peng, H & Marians, KJ (1993) Decatenation activity of topoisomerase IV during oriC and pBR322 DNA replication in vitro. Proc. Natl. Acad. Sci. U.S.A. 90 8571-5 PubMed
- ↑ 12.0 12.1 12.2 12.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 13.00 13.01 13.02 13.03 13.04 13.05 13.06 13.07 13.08 13.09 13.10 13.11 13.12 13.13 13.14 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
Categories
- GO:0003677 ! DNA binding
- GO:0003916 ! DNA topoisomerase activity
- GO:0003918 ! DNA topoisomerase type II (ATP-hydrolyzing) activity
- GO:0005524 ! ATP binding
- GO:0005694 ! chromosome
- GO:0006265 ! DNA topological change
- GO:0006268 ! DNA unwinding involved in DNA replication
- GO:0016020 ! membrane
- GO:0016853 ! isomerase activity
- GO:0005737 ! cytoplasm
- GO:0006261 ! DNA-dependent DNA replication
- GO:0007059 ! chromosome segregation
- GO:0019897 ! extrinsic component of plasma membrane
- GO:0009330 ! DNA topoisomerase complex (ATP-hydrolyzing)
- GO:0030541 ! plasmid partitioning
- Proteins
- Complex:dimer of topoisomerase IV subunit A
- Complex:topoisomerase IV
- Location:cytoplasm
- Products with structures in PDB
- GO Annotation by EcoliWiki Team