mreB:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
MreB |
|---|---|
| Synonyms |
cell wall structural complex MreBCD, actin-like component MreB[1], B3251[2][1], RodY[2][1], Mon[2][1], EnvB[2][1], MreB_1[2][1], MreB[2][1] , ECK3239, envB, JW3220, mon, rodY, b3251 |
| Product description |
Component of longitudinal peptidoglycan synthesis/chromosome segregation-directing complex[3] MreB filaments participate in directional chromosome movement and segregation; mecillinam resistance; forms membrane-associated coiled arrays; actin homolog; morphology[4] |
| EC number (for enzymes) |
|
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000902 |
cell morphogenesis |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0008360 |
regulation of cell shape |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0051983 |
regulation of chromosome segregation |
IGI: Inferred from Genetic Interaction |
EcoliWiki:mreC|EcoliWiki:mreD |
P |
complete | |||
| GO:0051983 |
regulation of chromosome segregation |
IGI: Inferred from Genetic Interaction |
P |
Seeded from EcoCyc (v14.0) |
Missing: with/from | |||
| GO:0051983 |
regulation of chromosome segregation |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of longitudinal peptidoglycan synthesis/chromosome segregation-directing complex |
could be indirect |
||
|
Protein |
accA |
Experiment(s):EBI-888239 | ||
|
Protein |
add |
Experiment(s):EBI-888239 | ||
|
Protein |
atpD |
Experiment(s):EBI-888239 | ||
|
Protein |
clpB |
Experiment(s):EBI-888239 | ||
|
Protein |
dnaK |
Experiment(s):EBI-888239, EBI-893751 | ||
|
Protein |
fusA |
Experiment(s):EBI-888239 | ||
|
Protein |
gatY |
Experiment(s):EBI-888239 | ||
|
Protein |
glyQ |
Experiment(s):EBI-888239 | ||
|
Protein |
gyrA |
Experiment(s):EBI-888239, EBI-884206 | ||
|
Protein |
kefC |
Experiment(s):EBI-888239 | ||
|
Protein |
lysU |
Experiment(s):EBI-888239 | ||
|
Protein |
malK |
Experiment(s):EBI-888239 | ||
|
Protein |
malT |
Experiment(s):EBI-888239, EBI-879887 | ||
|
Protein |
minD |
Experiment(s):EBI-888239 | ||
|
Protein |
groL |
Experiment(s):EBI-888239, EBI-893751 | ||
|
Protein |
narG |
Experiment(s):EBI-888239, EBI-880367 | ||
|
Protein |
nuoC |
Experiment(s):EBI-888239 | ||
|
Protein |
ompA |
Experiment(s):EBI-888239 | ||
|
Protein |
ompC |
Experiment(s):EBI-888239 | ||
|
Protein |
pnp |
Experiment(s):EBI-888239, EBI-883913 | ||
|
Protein |
pstB |
Experiment(s):EBI-888239, EBI-878876 | ||
|
Protein |
recA |
Experiment(s):EBI-888239 | ||
|
Protein |
rho |
Experiment(s):EBI-888239 | ||
|
Protein |
rplE |
Experiment(s):EBI-888239 | ||
|
Protein |
rpoB |
Experiment(s):EBI-888239 | ||
|
Protein |
rpoC |
Experiment(s):EBI-888239 | ||
|
Protein |
secA |
Experiment(s):EBI-888239, EBI-880477, EBI-893751 | ||
|
Protein |
radA |
Experiment(s):EBI-888239 | ||
|
Protein |
tufA |
Experiment(s):EBI-888239, EBI-889981, EBI-893751 | ||
|
Protein |
yleA |
Experiment(s):EBI-888239, EBI-879008 | ||
|
Protein |
ydiH |
Experiment(s):EBI-893751 | ||
|
Protein |
gatB |
Experiment(s):EBI-893751 | ||
|
Protein |
rplC |
Experiment(s):EBI-893751 | ||
|
Protein |
rpsF |
Experiment(s):EBI-893751 | ||
|
Protein |
uspG |
Experiment(s):EBI-893751 | ||
|
Protein |
ybeD |
Experiment(s):EBI-893751 | ||
|
Protein |
yjgD |
Experiment(s):EBI-893751 | ||
|
Protein |
rraB |
LCMS(ID Probability):99.6 | ||
|
Protein |
ydiH |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsF |
LCMS(ID Probability):99.6 | ||
|
Protein |
pnp |
MALDI(Z-score):22.799859 | ||
|
Protein |
groL |
LCMS(ID Probability):99.6 MALDI(Z-score):17.053160 | ||
|
Protein |
groS |
LCMS(ID Probability):99.6 MALDI(Z-score):24.893345 | ||
|
Protein |
rplE |
MALDI(Z-score):21.654832 | ||
|
Protein |
nusG |
LCMS(ID Probability):99.6 MALDI(Z-score):38.493587 | ||
|
Protein |
rho |
MALDI(Z-score):33.870882 | ||
|
Protein |
atpD |
MALDI(Z-score):20.723497 | ||
|
Protein |
secA |
LCMS(ID Probability):99.6 MALDI(Z-score):37.736144 | ||
|
Protein |
minD |
MALDI(Z-score):18.389853 | ||
|
Protein |
fusA |
MALDI(Z-score):23.873733 | ||
|
Protein |
nuoC |
MALDI(Z-score):23.126243 | ||
|
Protein |
ibpA |
LCMS(ID Probability):99.6 MALDI(Z-score):17.053160 | ||
|
Protein |
miaB |
LCMS(ID Probability):83.7 MALDI(Z-score):34.493869 | ||
|
Protein |
dnaJ |
LCMS(ID Probability):99.6 MALDI(Z-score):34.695952 | ||
|
Protein |
gatZ |
MALDI(Z-score):29.093011 | ||
|
Protein |
uspG |
LCMS(ID Probability):99.6 MALDI(Z-score):7.859012 | ||
|
Protein |
gatB |
LCMS(ID Probability):99.6 | ||
|
Protein |
ybeD |
LCMS(ID Probability):99.6 | ||
|
Protein |
ompC |
MALDI(Z-score):30.421807 | ||
|
Protein |
recA |
MALDI(Z-score):29.479724 | ||
|
Protein |
ftsZ |
LCMS(ID Probability):97.2 MALDI(Z-score):30.059500 | ||
|
Protein |
pstB |
MALDI(Z-score):35.461003 | ||
|
Protein |
add |
MALDI(Z-score):34.358029 | ||
|
Protein |
gatY |
MALDI(Z-score):25.064105 | ||
|
Protein |
malK |
MALDI(Z-score):19.548643 | ||
|
Protein |
ParC |
| ||
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MVGKVSGFSF PPQLSGLSLS MLKKFRGMFS NDLSIDLGTA NTLIYVKGQG IVLNEPSVVA IRQDRAGSPK SVAAVGHDAK QMLGRTPGNI AAIRPMKDGV IADFFVTEKM LQHFIKQVHS NSFMRPSPRV LVCVPVGATQ VERRAIRESA QGAGAREVFL IEEPMAAAIG AGLPVSEATG SMVVDIGGGT TEVAVISLNG VVYSSSVRIG GDRFDEAIIN YVRRNYGSLI GEATAERIKH EIGSAYPGDE VREIEVRGRN LAEGVPRGFT LNSNEILEAL QEPLTGIVSA VMVALEQCPP ELASDISERG MVLTGGGALL RNLDRLLMEE TGIPVVVAED PLTCVARGGG KALEMIDMHG GDLFSEE |
| Length |
367 |
| Mol. Wt |
38.972 kDa |
| pI |
5.2 (calculated) |
| Extinction coefficient |
7,450 - 7,825 (calc based on 5 Y, 0 W, and 3 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 Madabhushi, R & Marians, KJ (2009) Actin homolog MreB affects chromosome segregation by regulating topoisomerase IV in Escherichia coli. Mol. Cell 33 171-80 PubMed
- ↑ Kruse, T et al. (2003) Dysfunctional MreB inhibits chromosome segregation in Escherichia coli. EMBO J. 22 5283-92 PubMed
- ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 7.21 7.22 7.23 7.24 7.25 7.26 7.27 7.28 7.29 7.30 7.31 7.32 7.33 7.34 7.35 7.36 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 8.13 8.14 8.15 8.16 8.17 8.18 8.19 8.20 8.21 8.22 8.23 8.24 8.25 8.26 8.27 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
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