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On One Page

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Gene |

Product(s) |

Expression|

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Standard Name	yehQ
Gene Synonym(s)	ECK2114, b2122, JW2110^[1], JW2110
Product Desc.	conserved protein^[2]; predicted protein^[3]
Product Synonyms(s)	predicted protein^[1], B2122^[2]^[1], YehQ^[2]^[1] , ECK2114, JW2110, b2122
Function from GO	<GO_nr />
Knock-Out Phenotype
Regulation/Expression	transcription unit(s): yehL^[2]
Regulation/Activity
Quick Links
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Notes

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Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name	yehQ
Mnemonic
Synonyms	ECK2114, b2122, JW2110^[1], JW2110
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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain	Map location	Genome coordinates	Genome browsers	Sequence links
MG1655	47.57 minutes	MG1655: 2207122..2208966 <gbrowseImage> name=NC_000913:2207122..2208966 source=MG1655 preset=GeneLocation </gbrowseImage>	EcoCyc GBrowse(MG1655)	FASTA Dump EcoCyc Sequence Dump
REL606		NC_012967: 2160296..2162296 <gbrowseImage> name=NC_012967:2160296..2162296 source=REL606 preset=GeneLocation </gbrowseImage>	GBrowse (REL606)	FASTA Dump
W3110		W3110: 2212434..2214278 <gbrowseImage> name=NC_007779:2212434..2214278 source=W3110 preset=GeneLocation </gbrowseImage>	GBrowse(W3110)	FASTA Dump
DH10B		DH10B: 2298130..2299974 <gbrowseImage> name=NC_010473:2298130..2299974 source=DH10B preset=GeneLocation </gbrowseImage>	GBrowse(DH10B)	FASTA Dump
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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type	Strain	Genomic Location	Evidence	Reference	Notes
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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele	Nt change(s)	AA change(s)	Reference	Availability	Comments
ΔyehQ (Keio:JW2110)	deletion	deletion	PMID:16738554	Shigen CGSC9713^[4]
yehQ::Tn5KAN-I-SceI (FB20624)	Insertion at nt 1296 in Minus orientation		PMID:15262929	E. coli Genome Project:FB20624	contains pKD46
ΔyehQ747::kan			PMID:16738554	CGSC:104550
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Notes

Genetic Interactions

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Interactor	Interaction	Allele	Score(s)	Reference(s)	Accessions	Notes
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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource	Resource Type	Source	Notes/Reference
JW2110	Plasmid clone	Shigen	PMID:16769691 Status:Clone OK Primer 1:GCCAATTCACTACGTCCGGAATT Primer 2:CCTGCCTGACCAATAGCACTCTG
17A4	Kohara Phage	Genobase	PMID:3038334
zbd-3104::Tn10	Linked marker	CAG12021 = CGSC7344^[4]	est. P1 cotransduction: 29% ^[5] Synonyms:zbc-3105::Tn10, zbd-3105::Tn10
napA722::Tn10	Linked marker	CAG12098 = CGSC7400^[4]	est. P1 cotransduction: % ^[5] Synonyms:zeg-722, zei-722::Tn10
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc	EcoCyc:EG12003	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG12003	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001922	Escherichia coli str. K-12 substr. MG1655
NCBI (EcoliWiki Page)	GeneID:946654	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1941	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0007015	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name	YehQ
Synonyms	predicted protein^[1], B2122^[2]^[1], YehQ^[2]^[1] , ECK2114, JW2110, b2122
Product description	conserved protein^[2]; predicted protein^[3]
EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0008270	zinc ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007527	F	Seeded from EcoCyc (v14.0)	complete
	GO:0008270	zinc ion binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0862	F	Seeded from EcoCyc (v14.0)	complete
	GO:0046872	metal ion binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F	Seeded from EcoCyc (v14.0)	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	References	Evidence
Protein	pdxJ	PMID:16606699	Experiment(s):EBI-1141976
Protein	xapA	PMID:16606699	Experiment(s):EBI-1141976
Protein	groL	PMID:16606699	Experiment(s):EBI-1141976
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MACGESSVMN SLRPELLELT PQALTALSNA GFVKRSLKEL ENGNVPEISH ENDALIATFS DGVRTQLANG QALKEAQCSC GANGMCRHRV MLVLSYQRLC ATTQSTEKEE EWDPAIWLEE LATLPDATRK RAQALVAKGI TIELFCAPGE IPSARLPMSD VRFYSRSSIR FARCDCIEGT LCEHVVLAVQ AFVEAKAQQA EFNHLIWQMR SEHVTSSDDP FASEEGNACR QYVQQLSQTL WLGGISQPLI HYEAAFNRAL QAAETCNWRW VSESLRQLRA SVDAFHARAS HYNAGECLHQ LAALNSRLNC AQEMARRDSI GEVPPVPWRT VVGSGIAGEA KLDHLRLVSL GMRCWQDIEH YGLRIWFTDP DTGSILHLSR SWPRSEQENS PAATRRLFSF QAGALAGGQI VSQAAKRSAD GELLLATRNR LSSVVPLSPD AWQMLSAPLR QPGIVALREY LRQRPPACIR PLNQVDNLFI LPVAECISLG WDSSRQTLDA QVISGEGEDN VLTLSLPASA SAPYAVERMA ALLQQTDDPV CLVSGFVSFV EGQLTLEPRV MMTKTRAWAL DAETTPVAPL PSASVLPVPS TAHQLLIRCQ ALLIQLLHNG WRYQEQSAIG QA
Length	622
Mol. Wt	68.494 kDa
pI	6.1 (calculated)
Extinction coefficient	90,410 - 92,660 (calc based on 9 Y, 14 W, and 18 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	References
Domain	55..89	PF04434 SWIM zinc finger	PMID:19920124
Domain	144..184	PF04434 SWIM zinc finger	PMID:19920124
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yehQ taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
ASAP	ASAP:ABE-0007015	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:946654	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P33353	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:EG12003	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG12003	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:946654	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001922	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1941	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Cellular Levels

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See Help:Cellular levels

Molecule	Organism or Strain	Value	Units	Experimental Conditions	Assay used	Notes	Reference(s)
Protein	E. coli K-12 MC4100	1.12E+02	molecules/cell	Medium: median data from rich and minimal media Temperature (°C): 37 Doubling time (min): Growth Rate(min): Growth phase: other:	emPAI		PMID:18304323
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Notes

Transcription and Transcriptional Regulation

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)
yehL
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Figure courtesy of RegulonDB

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Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000913:2207102..2207142 source=MG1655 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name	Mutation	Phenotype	Reference
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Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type	Reference	Notes
microarray	GEO Profiles:b2122 (EcoliWiki Page)	NCBI GEO profiles for yehQ
microarray	GenExpDB:b2122 (EcoliWiki Page)	Summary of data for yehQ from multiple microarray studies
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Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name	Resource Type	Description	Source	Notes
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Notes

Accessions Related to yehQ Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc	EcoCyc:EG12003	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1941	Escherichia coli str. K-12 substr. MG1655
EcoliGenExpDB (EcoliWiki Page)	EcoliGenExpDB:b2122
EcoGene	EcoGene:EG12003	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001922	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0007015	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism	Homologs (Statistics)	Comments
Shigella flexneri	YEHQ	From SHIGELLACYC
E. coli O157	YEHQ	From ECOO157CYC
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Do-It-Yourself Web Tools

Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
Pfam (EcoliWiki Page)	PF04434 SWIM zinc finger
Pfam (EcoliWiki Page)	PF04434 SWIM zinc finger
EcoCyc	EcoCyc:EG12003	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG12003	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001922	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1941	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0007015	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^4.0 ^4.1 ^4.2 CGSC: The Coli Genetics Stock Center
↑ ^5.0 ^5.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).

yehQ:On One Page

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Notes

Gene

Nomenclature

Notes

Location(s) and DNA Sequence

Notes

Sequence Features

Notes

Alleles and Phenotypes

Notes

Genetic Interactions

Notes

Genetic Resources

Notes

Accessions in Other Databases

Notes

Links

Product(s)

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

Expression

Overview

Cellular Levels

Notes

Transcription and Transcriptional Regulation

Notes

Translation and Regulation of Translation

Notes

Turnover and Regulation of Turnover

Notes

Experimental

Notes

Accessions Related to yehQ Expression

Notes

Links

Evolution

Homologs in Other Organisms

Do-It-Yourself Web Tools

Notes

Families

Notes

Links

References

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