uvrD:Gene
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Location(s) and DNA Sequence | Sequence Features | Alleles and Phenotypes | Genetic Interactions | Genetic Resources | Accessions | Links | References | Suggestions |
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Nomenclature
See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.
| Standard name |
uvrD |
|---|---|
| Mnemonic |
UV resistant |
| Synonyms |
ECK3808, b3813, JW3786, dar-2, dda, mutU, pdeB, rad, recL, srjC, uvr502, uvrE[1], uvrE |
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Notes
Location(s) and DNA Sequence
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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.
| Strain | Map location | Genome coordinates | Genome browsers | Sequence links |
|---|---|---|---|---|
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MG1655 |
86.13 minutes, 86.13 minutes |
MG1655: 3996006..3998168 |
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NC_012967: 3959820..3961982 |
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NC_012759: 3885675..3887837 |
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W3110 |
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W3110: 3638698..3636536 |
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DH10B: 4094926..4097088 |
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Notes
Sequence Features
See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.
| Feature Type | Strain | Genomic Location | Evidence | Reference | Notes |
|---|---|---|---|---|---|
|
Coding Start (SO:0000323) |
3996006 |
Edman degradation |
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Notes
Alleles and Phenotypes
See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.
| Allele | Nt change(s) | AA change(s) | Phenotype: Type | Phenotype: Description | Reference | Availability | Comments |
|---|---|---|---|---|---|---|---|
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ΔuvrD (Keio:JW3786) |
deletion |
deletion |
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uvrDG30D |
G30D |
(in uvrD252, which is UV sensitive) |
Strain variation; seeded from UniProt:P03018 | ||||
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uvrD3 |
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uvrD156 |
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uvrD252 |
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uvrD502 |
PMID:4345920[6] PMID:4946852[7] PMID:4576008[8] PMID:5341964[9] |
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uvrD282::Tn5 |
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uvrD291(del-ins,::tet) |
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ΔuvrD769::kan |
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Notes
Genetic Interactions
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| Interactor | Interaction | Allele | Score(s) | Reference(s) | Accessions | Notes |
|---|---|---|---|---|---|---|
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Notes
Genetic Resources
See Help:Gene_resources for help entering information into the Genetic Resources table.
| Resource | Resource Type | Source | Notes/Reference |
|---|---|---|---|
|
JW3786 |
Plasmid clone |
Status:Clone OK Primer 1:GCCGACGTTTCTTACCTGCTCGA Primer 2:CCaACCGACTCCAGCCGGGCGTA | |
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Kohara Phage |
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Kohara Phage |
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Linked marker |
est. P1 cotransduction: 15% [12] | ||
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metEo-3079::Tn10 |
Linked marker |
est. P1 cotransduction: 64% [12] | |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
| Name | URL | Comments |
|---|---|---|
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References
See Help:References for how to manage references in EcoliWiki.
- ↑ Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ Yamamoto, Y et al. (1986) Determination of the initiation sites of transcription and translation of the uvrD gene of Escherichia coli. J. Biochem. 99 1579-90 PubMed
- ↑ 3.0 3.1 Baba, T et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2 2006.0008 PubMed
- ↑ 4.0 4.1 4.2 CGSC: The Coli Genetics Stock Center
- ↑ Washburn, BK & Kushner, SR (1993) Characterization of DNA helicase II from a uvrD252 mutant of Escherichia coli. J. Bacteriol. 175 341-50 PubMed
- ↑ Siegel, EC (1973) Ultraviolet-sensitive mutator strain of Escherichia coli K-12. J. Bacteriol. 113 145-60 PubMed
- ↑ Smirnov, GB & Skavronskaya, AG (1971) Location of uvr502 mutation on the chromosome of Escherichia coli K-12. Mol. Gen. Genet. 113 217-21 PubMed
- ↑ Smirnov, GB et al. (1972) The mutator property of uvr502 mutation affecting UV sensitivity of Escherichia coli. Mol. Gen. Genet. 118 51-6 PubMed
- ↑ van de Putte, P et al. (1965) The location of genes controlling radiation sensitivity in Escherichia coli. Mutat. Res. 2 97-110 PubMed
- ↑ Kitagawa, M et al. (2005) Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. DNA Res. 12 291-9 PubMed
- ↑ 11.0 11.1 Kohara, Y et al. (1987) The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50 495-508 PubMed
- ↑ 12.0 12.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
