tauA:On One Page

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

Quickview

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Standard Name

tauA

Gene Synonym(s)

ECK0362, b0365, JW0357, ssiA, yaiR[1], yaiR

Product Desc.

TauA[2][3];

Component of TauA/TauB/TauC ABC transporter[2]; taurine ABC transporter[3]

Periplasmic taurine binding protein[4]

Product Synonyms(s)

taurine transporter subunit[1], periplasmic-binding component of ABC superfamily[1], B0365[2][1], YaiR[2][1], SsiA[2][1], TauA[2][1], taurine transport system periplasmic protein[2][1] , ECK0362, JW0357, ssiA, yaiR, b0365

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): tauABCD[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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tauA and ssuA are paralogs.[4]



Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

tauA

Mnemonic

Taurine

Synonyms

ECK0362, b0365, JW0357, ssiA, yaiR[1], yaiR

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

8.29 minutes 

MG1655: 384456..385418
<gbrowseImage> name=NC_000913:384456..385418 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 354140..355102
<gbrowseImage> name=NC_012967:354140..355102 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 287215..288177
<gbrowseImage> name=NC_012759:287215..288177 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 384456..385418
<gbrowseImage> name=NC_007779:384456..385418 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 323787..324749
<gbrowseImage> name=NC_010473:323787..324749 source=DH10B preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

Coding Start (SO:0000323)

MG1655

384522

Edman degradation

PMID:8774726


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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

tauA(del) (Keio:JW0357)

deletion

deletion

PMID:16738554

Shigen

CGSC8542[5]

tauA733(del)::kan

PMID:16738554

CGSC:103100


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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes

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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

Plasmid clone

Shigen

PMID:16769691

Status:

Primer 1:

Primer 2:

8F10

Kohara Phage

Genobase

PMID:3038334

mhpC281::Tn10

Linked marker

CAG12080 = CGSC7333[5]

est. P1 cotransduction: 63% [6]
Synonyms:zah-281::Tn10

zai-3053::Tn10

Linked marker

CAG18091 = CGSC7336[5]

est. P1 cotransduction: 71% [6]
Synonyms:zaj-3053::Tn10 nnnCAG18091 also carries proC9999 (CGSC).

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:G6217

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13300

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002831

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:945030

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3085

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0001256

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

TauA

Synonyms

taurine transporter subunit[1], periplasmic-binding component of ABC superfamily[1], B0365[2][1], YaiR[2][1], SsiA[2][1], TauA[2][1], taurine transport system periplasmic protein[2][1] , ECK0362, JW0357, ssiA, yaiR, b0365

Product description

TauA[2][3];

Component of TauA/TauB/TauC ABC transporter[2]; taurine ABC transporter[3]

Periplasmic taurine binding protein[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0005215

transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001638

F

Seeded from EcoCyc (v14.0)

complete

GO:0005215

transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007210

F

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001638

P

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007210

P

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc (v14.0)

complete

GO:0030288

outer membrane-bounded periplasmic space

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001638

C

Seeded from EcoCyc (v14.0)

complete

GO:0042597

periplasmic space

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0574

C

Seeded from EcoCyc (v14.0)

complete

GO:0042597

periplasmic space

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0200

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of TauA/TauB/TauC ABC transporter

could be indirect

Protein

tnaA

PMID:16606699

Experiment(s):EBI-1136381

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

Periplasm

PMID:8774726

EchoLocation:tauA


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MNVFIPEYCS HNKTGEQTIM AISSRNTLLA ALAFIAFQAQ AVNVTVAYQT SAEPAKVAQA
DNTFAKESGA TVDWRKFDSG ASIVRALASG DVQIGNLGSS PLAVAASQQV PIEVFLLASK
LGNSEALVVK KTISKPEDLI GKRIAVPFIS TTHYSLLAAL KHWGIKPGQV EIVNLQPPAI
IAAWQRGDID GAYVWAPAVN ALEKDGKVLT DSEQVGQWGA PTLDVWVVRK DFAEKHPEVV
KAFAKSAIDA QQPYIANPDV WLKQPENISK LARLSGVPEG DVPGLVKGNT YLTPQQQTAE
LTGPVNKAII DTAQFLKEQG KVPAVANDYS QYVTSRFVQ
Length

339

Mol. Wt

36.458 kDa

pI

6.9 (calculated)

Extinction coefficient

50,420 - 50,545 (calc based on 8 Y, 7 W, and 1 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-22

UniProt Manual:Signal Peptides

UniProt:Q47537

Domain

23..252

PF04069 Substrate binding domain of ABC-type glycine betaine transport system

PMID:19920124

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=tauA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111122

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945030

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0001256

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:Q47537

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6217

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13300

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945030

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002831

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3085

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Protein

E. coli K-12 MG1655

3a

molecules/cell/generation

  • Medium: MOPS Complete
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

Low confidence in the sequencing data set.

PMID: 24766808

Protein

E. coli K-12 MG1655

39

molecules/cell/generation

  • Medium: MOPS Minimal
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

231

molecules/cell/generation

  • Medium: MOPS Complete without Methionine
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Notes

Transcription and Transcriptional Regulation

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<protect>

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

tauABCD

Figure courtesy of RegulonDB

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Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000913:384436..384476 source=MG1655 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference


Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b0365 (EcoliWiki Page)

NCBI GEO profiles for tauA

microarray

GenExpDB:b0365 (EcoliWiki Page)

Summary of data for tauA from multiple microarray studies


Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes

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Notes

Accessions Related to tauA Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:G6217

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3085

Escherichia coli str. K-12 substr. MG1655

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b0365

EcoGene

EcoGene:EG13300

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002831

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0001256

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments

Shigella flexneri

TAUA

From SHIGELLACYC

E. coli O157

TAUA

From ECOO157CYC


Do-It-Yourself Web Tools

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Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

Pfam (EcoliWiki Page)

PF04069 Substrate binding domain of ABC-type glycine betaine transport system

Superfamily (EcoliWiki Page)

SUPERFAMILY:53850

EcoCyc

EcoCyc:G6217

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13300

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002831

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3085

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0001256

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 CGSC: The Coli Genetics Stock Center
  6. 6.0 6.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).

Categories

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