pepA:On One Page

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

Quickview

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

<protect>

Standard Name

pepA

Gene Synonym(s)

ECK4253, b4260, JW4217, carP, xerB[1], xerB

Product Desc.

PepA Transcriptional Repressor, Aminopeptidase A/I[2][3]

Multifunctional Aminopeptidase A; transcriptional regulator of carAB; non-peptidase, DNA-binding role in site-specific recombination mediating ColE1 plasmid multimer resolution; homohexameric[4]

Product Synonyms(s)

aminopeptidase A, a cyteinylglycinase[1], PepA[2][1], B4260[2][1], XerB[2][1], CarP[2][1] , carP, ECK4253, JW4217, xerB, b4260

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): pepA[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

edit table

</protect> See Help:Quickview for help with entering information in the Quickview table. <protect></protect>

Notes

[back to top]


PepA has a broad specificity for successive removal of many N-terminal amino acids, although leucine is preferred as the residue N-terminal to the cleavage site.[4]



Gene

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css> <protect>

Nomenclature

[back to top]


See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

pepA

Mnemonic

Peptidase

Synonyms

ECK4253, b4260, JW4217, carP, xerB[1], xerB

edit table

</protect>

Notes

Location(s) and DNA Sequence

[back to top]


<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

96.61 minutes, 96.61 minutes 

MG1655: 4483974..4482463
<gbrowseImage> name=NC_000913:4482463..4483974 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 4469178..4467667
<gbrowseImage> name=NC_012967:4467667..4469178 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 4421198..4422709
<gbrowseImage> name=NC_012759:4421198..4422709 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 4490631..4489120
<gbrowseImage> name=NC_007779:4489120..4490631 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 4585782..4584271
<gbrowseImage> name=NC_010473:4584271..4585782 source=DH10B preset=GeneLocation </gbrowseImage>

edit table

</protect>

Notes

Sequence Features

[back to top]


See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

Coding Start (SO:0000323)

MG1655

4482463

Edman degradation

PMID:2670557


edit table

<protect></protect>

Notes

Alleles and Phenotypes

[back to top]


See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

pepAE354A

E354A

Loss of activity

seeded from UniProt:P68767

ΔpepA (Keio:JW4217)

deletion

deletion

PMID:16738554

Shigen
CGSC11034[5]

ΔpepA733::kan

PMID:16738554

CGSC:102278

carP6

TGG (W473) into a TAG (amber stop)

confers partial constitutive expression to the carAB promoter P1 and is trans-dominant over the wt gene

PMID:7616564

xerB1

Tn5 insertion that affects the regulation of carAB expression

PMID:7616564


edit table

<protect></protect>

Notes

Genetic Interactions

[back to top]


<protect>

Interactor Interaction Allele Score(s) Reference(s) Accessions Notes
edit table

</protect>

Notes

Genetic Resources

[back to top]


See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW4217

Plasmid clone

Shigen

PMID:16769691

Status:Clone OK

Primer 1:GCCGAGTTTAGTGTAAAAAGCGG

Primer 2:CCtTCTTCGCCGTTAAACCCAGC

E1F5

Kohara Phage

Genobase

PMID:3038334

5C4

Kohara Phage

Genobase

PMID:3038334

E4D8

Kohara Phage

Genobase

PMID:3038334

zjf-920::Tn10

Linked marker

CAG12019 = CGSC7484[5]

est. P1 cotransduction: 21% [6]
Synonyms:zjh-901::Tn10, zjg-920::Tn10

mdoB202::Tn10

Linked marker

CAG18430 = CGSC7488[5]

est. P1 cotransduction: % [6]
Synonyms:zjj-202::Tn10, zji-202::Tn10

edit table

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10694

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10694

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000686

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:948791

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0688

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013953

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]



Product(s)

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

PepA

Synonyms

aminopeptidase A, a cyteinylglycinase[1], PepA[2][1], B4260[2][1], XerB[2][1], CarP[2][1] , carP, ECK4253, JW4217, xerB, b4260

Product description

PepA Transcriptional Repressor, Aminopeptidase A/I[2][3]

Multifunctional Aminopeptidase A; transcriptional regulator of carAB; non-peptidase, DNA-binding role in site-specific recombination mediating ColE1 plasmid multimer resolution; homohexameric[4]

EC number (for enzymes)
edit table

<protect></protect>

Notes

The xerB synonym was given when mutant alleles were isolated that are defective in site-specific recombination at the plasmid ColE1 cer locus.[7][8]

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0004177

aminopeptidase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00181

F

Seeded from EcoCyc (v14.0)

complete

GO:0004177

aminopeptidase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000819

F

Seeded from EcoCyc (v14.0)

complete

GO:0004177

aminopeptidase activity

PMID:2670557

IDA: Inferred from Direct Assay

F

complete

GO:0004177

aminopeptidase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008283

F

Seeded from EcoCyc (v14.0)

complete

GO:0004177

aminopeptidase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011356

F

Seeded from EcoCyc (v14.0)

complete

GO:0004177

aminopeptidase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0031

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000819

C

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008283

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00181

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011356

C

Seeded from EcoCyc (v14.0)

complete

GO:0006508

proteolysis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000819

P

Seeded from EcoCyc (v14.0)

complete

GO:0006508

proteolysis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008283

P

Seeded from EcoCyc (v14.0)

complete

GO:0008233

peptidase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0645

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

PMID:7616564

IDA: Inferred from Direct Assay

F

complete

GO:0008235

metalloexopeptidase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00181

F

Seeded from EcoCyc (v14.0)

complete

GO:0008235

metalloexopeptidase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011356

F

Seeded from EcoCyc (v14.0)

complete

GO:0001073

DNA binding transcription antitermination factor activity

PMID:7616564

IMP: Inferred from Mutant Phenotype

F

regulation of the carAB operon

replaced obsolete GO:0016564

complete

GO:0016564

transcription repressor activity

PMID:7616564

IMP: Inferred from Mutant Phenotype

F

Seeded from EcoCyc (v14.0)

complete

GO:0016787

hydrolase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded from EcoCyc (v14.0)

complete

GO:0043171

peptide catabolic process

PMID:355237

IMP: Inferred from Mutant Phenotype

P

complete

GO:0042150

plasmid recombination

PMID:2670557

IMP: Inferred from Mutant Phenotype

P

XerC, XerD, ArgR, and PepA, are required for site-specific recombination at the ColE1 cer locus in E. coli K-12 (see references in [9]).

complete

GO:0019538

protein metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011356

P

Seeded from EcoCyc (v14.0)

complete

GO:0030145

manganese ion binding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00181

F

Seeded from EcoCyc (v14.0)

complete

GO:0030145

manganese ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011356

F

Seeded from EcoCyc (v14.0)

complete

GO:0030145

manganese ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0464

F

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc (v14.0)

complete

GO:0006276

plasmid maintenance

PMID:2670557

IMP: Inferred from Mutant Phenotype

P

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

sucB

PMID:16606699

Experiment(s):EBI-1147774

Protein

pyrB

PMID:16606699

Experiment(s):EBI-1147774

Protein

lacZ

PMID:16606699

Experiment(s):EBI-1147774

Protein

lysU

PMID:19402753

MALDI(Z-score):28.486162

Protein

pepD

PMID:19402753

LCMS(ID Probability):99.6 MALDI(Z-score):27.154431

edit table

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
edit table

<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MEFSVKSGSP EKQRSACIVV GVFEPRRLSP IAEQLDKISD GYISALLRRG ELEGKPGQTL
LLHHVPNVLS ERILLIGCGK ERELDERQYK QVIQKTINTL NDTGSMEAVC FLTELHVKGR
NNYWKVRQAV ETAKETLYSF DQLKTNKSEP RRPLRKMVFN VPTRRELTSG ERAIQHGLAI
AAGIKAAKDL GNMPPNICNA AYLASQARQL ADSYSKNVIT RVIGEQQMKE LGMHSYLAVG
QGSQNESLMS VIEYKGNASE DARPIVLVGK GLTFDSGGIS IKPSEGMDEM KYDMCGAAAV
YGVMRMVAEL QLPINVIGVL AGCENMPGGR AYRPGDVLTT MSGQTVEVLN TDAEGRLVLC
DVLTYVERFE PEAVIDVATL TGACVIALGH HITGLMANHN PLAHELIAAS EQSGDRAWRL
PLGDEYQEQL ESNFADMANI GGRPGGAITA GCFLSRFTRK YNWAHLDIAG TAWRSGKAKG
ATGRPVALLA QFLLNRAGFN GEE
Length

503

Mol. Wt

54.88 kDa

pI

7.3 (calculated)

Extinction coefficient

42,860 - 43,985 (calc based on 14 Y, 4 W, and 9 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

19..147

PF02789 Cytosol aminopeptidase family, N-terminal domain

PMID:19920124

Domain

184..491

PF00883 Cytosol aminopeptidase family, catalytic domain

PMID:19920124

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=pepA taxon=562,83333 </beststructure>

Models

View models at:

edit table
</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16132082

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948791

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013953

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P68767

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10694

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10694

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948791

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000686

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0688

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]




Expression

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

[back to top]


See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Protein

E. coli K-12 MC4100

5.77E+02

molecules/cell

  • Medium: median data from rich and minimal media
  • Temperature (°C): 37
  • Doubling time (min): Growth Rate(min):
  • Growth phase: other:

emPAI

PMID:18304323

Protein

E. coli K-12 MG1655

2548

molecules/cell/generation

  • Medium: MOPS Complete
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

1308

molecules/cell/generation

  • Medium: MOPS Minimal
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

2563

molecules/cell/generation

  • Medium: MOPS Complete without Methionine
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

edit table

Notes

Transcription and Transcriptional Regulation

[back to top]


<protect>

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

pepA

edit table
Figure courtesy of RegulonDB

</protect>

Notes

Identification of the promoter region of carP and the regulation of its txn are discussed in reference [10]

Translation and Regulation of Translation

[back to top]


<protect><gbrowseImage> name=NC_000913:4483954..4483994 source=MG1655 flip=1 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

</protect>

Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

</protect>

Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

[back to top]


<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference
edit table


Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b4260 (EcoliWiki Page)

NCBI GEO profiles for pepA

microarray

GenExpDB:b4260 (EcoliWiki Page)

Summary of data for pepA from multiple microarray studies

edit table


Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes
edit table

<protect></protect>

Notes

Accessions Related to pepA Expression

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10694

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0688

Escherichia coli str. K-12 substr. MG1655

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b4260

EcoGene

EcoGene:EG10694

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000686

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013953

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]



Evolution

[back to top]


{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Homologs in Other Organisms

[back to top]


See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments

Anopheles gambiae

  • ENSANGP00000005638 (score: 1.000; bootstrap: 99%)
  • ENSANGP00000010036 (score: 0.200)
  • ENSANGP00000018393 (score: 0.194)

From Inparanoid:20070104

Apis mellifera

  • ENSAPMP00000031416 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Arabidopsis thaliana

  • AT4G30920 (score: 1.000; bootstrap: 100%)
  • AT4G30910 (score: 0.872)
  • AT2G24200 (score: 0.715)

From Inparanoid:20070104

Bos taurus

  • ENSBTAP00000007860 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Caenorhabditis briggsae

  • WBGene00037619 (score: 1.000; bootstrap: 94%)

From Inparanoid:20070104

Caenorhabditis elegans

  • WBGene00002249 (score: 1.000; bootstrap: 96%)

From Inparanoid:20070104

Canis familiaris

  • ENSCAFP00000022254 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Ciona intestinalis

  • ENSCINP00000016401 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Danio rerio

  • ZDB-GENE-050417-177 (score: 1.000; bootstrap: 97%)
  • ZDB-CDNA-050417-178 (score: 1.000; bootstrap: 97%)

From Inparanoid:20070104

Dictyostelium discoideum

  • DDB0231024 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Drosophila melanogaster

  • FBgn0052351 (score: 1.000; bootstrap: 100%)
  • FBgn0035915 (score: 0.887)
  • FBgn0034132 (score: 0.206)
  • FBgn0033860 (score: 0.206)
  • FBgn0045770 (score: 0.191)
  • FBgn0052064 (score: 0.191)
  • FBgn0033868 (score: 0.188)
  • FBgn0034134 (score: 0.176)

From Inparanoid:20070104

Drosophila pseudoobscura

  • GA18184-PA (score: 1.000; bootstrap: 98%)
  • GA14907-PA (score: 0.543)
  • GA18403-PA (score: 0.520)
  • GA16651-PA (score: 0.475)
  • GA12219-PA (score: 0.475)
  • GA19547-PA (score: 0.212)

From Inparanoid:20070104

Gallus gallus

  • ENSGALP00000028055 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Homo sapiens

  • ENSP00000226299 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Macaca mulatta

  • ENSMMUP00000007569 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Monodelphis domestica

  • ENSMODP00000001024 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Mus musculus

  • MGI:1914238 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Oryza gramene

  • Q6K669 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Pan troglodytes

  • ENSPTRP00000027448 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Rattus norvegicus

  • ENSRNOP00000004770 (score: 1.000; bootstrap: 99%)
  • ENSRNOP00000048929 (score: 0.464)

From Inparanoid:20070104

Schizosaccharomyces pombe

  • SPAC13A115 (score: 1.000; bootstrap: 100%)

From Inparanoid:20070104

Takifugu rubripes

  • NEWSINFRUP00000160378 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Tetraodon nigroviridis

  • GSTENP00007227001 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Xenopus tropicalis

  • ENSXETP00000044902 (score: 1.000; bootstrap: 99%)

From Inparanoid:20070104

Shigella flexneri

PEPA

From SHIGELLACYC

E. coli O157

PEPA

From ECOO157CYC

edit table


Do-It-Yourself Web Tools

<protect></protect>

Notes

Families

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

Pfam (EcoliWiki Page)

PF02789 Cytosol aminopeptidase family, N-terminal domain

Panther (EcoliWiki Page)

PTHR11963:SF3

Superfamily (EcoliWiki Page)

SUPERFAMILY:52949

Superfamily (EcoliWiki Page)

SUPERFAMILY:53187

Pfam (EcoliWiki Page)

PF00883 Cytosol aminopeptidase family, catalytic domain

EcoCyc

EcoCyc:EG10694

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10694

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000686

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0688

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013953

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]



References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 CGSC: The Coli Genetics Stock Center
  6. ↑ 6.0 6.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
  7. ↑ Stirling, CJ et al. (1988) Multicopy plasmid stability in Escherichia coli requires host-encoded functions that lead to plasmid site-specific recombination. Mol. Gen. Genet. 214 80-4 PubMed
  8. ↑ Stirling, CJ et al. (1989) xerB, an Escherichia coli gene required for plasmid ColE1 site-specific recombination, is identical to pepA, encoding aminopeptidase A, a protein with substantial similarity to bovine lens leucine aminopeptidase. EMBO J. 8 1623-7 PubMed
  9. ↑ Sherratt, DJ et al. (1995) Site-specific recombination and circular chromosome segregation. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 347 37-42 PubMed
  10. ↑ Charlier, D et al. (1995) carP, involved in pyrimidine regulation of the Escherichia coli carbamoylphosphate synthetase operon encodes a sequence-specific DNA-binding protein identical to XerB and PepA, also required for resolution of ColEI multimers. J. Mol. Biol. 250 392-406 PubMed

Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=pepA:On_One_Page&oldid=222651"