mnmE:On One Page
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
Quickview | | Gene | | Product(s) | | Expression| | Evolution | | References | |
Quickview
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Standard Name |
mnmE |
---|---|
Gene Synonym(s) | |
Product Desc. |
GTP-binding protein with a role in modification of tRNA[3][2] 5-methylaminomethyl-2-thiouridine modification at tRNA U34; cmnm(5) addition to tRNA-s(2)U34, forming (with subsequent or interdependent MnmG action) cmnm(5)s(2)U34-tRNA, an intermediate in mnm(5)s(2)U34-tRNA synthesis[4] |
Product Synonyms(s) |
GTPase[1], B3706[3][1], MnmE[3][1], TrmE[3][1], ThdF[3][1], O454[3][1] , ECK3699, JW3684, thdF, trmE, b3706 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression | |
Regulation/Activity | |
Quick Links | |
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Notes
GTPase activity is essential for modification function. Mutants are hypomodified for s(2)U34 in tRNA(Lys). The carboxymethylaminomethyl donor is unknown. U34 is the wobble base.mnmE has proposed to be epistatic to mnmG, preceding it in the pathway (Bregeon, 2001), but Yim (2000) suggest that the MnmE and MnmG activities are interdependent, not sequential. MnmG(GidA) and MnmE form a heterotetrameric complex (Yim, 2006).[4]
Gene
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Nomenclature
See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.
Standard name |
mnmE |
---|---|
Mnemonic |
Methyl-amino(N)-Methyl |
Synonyms | |
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Notes
Location(s) and DNA Sequence
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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.
Strain | Map location | Genome coordinates | Genome browsers | Sequence links |
---|---|---|---|---|
MG1655 |
83.73 minutes |
MG1655: 3884851..3886215 |
||
NC_012967: 3847189..3848553 |
||||
NC_012759: 3773184..3774548 |
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W3110 |
|
W3110: 3753587..3752223 |
||
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Notes
Sequence Features
See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.
Feature Type | Strain | Genomic Location | Evidence | Reference | Notes |
---|---|---|---|---|---|
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Notes
Alleles and Phenotypes
See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.
Allele | Nt change(s) | AA change(s) | Phenotype: Type | Phenotype: Description | Reference | Availability | Comments |
---|---|---|---|---|---|---|---|
mnmED338N |
D338N |
Strong decrease in GTP binding. Does not affect hydrolase activity, but has 10-fold higher affinity for XTP than for GTP. Partially impairs tRNA modifying function |
seeded from UniProt:P25522 | ||||
thdF::Tn5KAN-I-SceI (FB21404) |
Insertion at nt 378 in Plus orientation |
PMID:15262929 |
contains pKD46 | ||||
thdF::Tn5KAN-I-SceI (FB21405) |
Insertion at nt 378 in Plus orientation |
PMID:15262929 |
does not contain pKD46 | ||||
mnmET251S |
T251S |
4-fold decrease in GTPase activity and 1.2-fold decrease of affinity |
seeded from UniProt:P25522 | ||||
mnmER252A |
R252A |
7-fold decrease in GTPase activity and 6-fold increase of affinity |
seeded from UniProt:P25522 | ||||
mnmER288A |
R288A |
1.7-fold decrease in GTPase activity and 1.5-fold increase of affinity |
seeded from UniProt:P25522 | ||||
mnmEG249A |
G249A |
22-fold decrease in GTPase activity and 7-fold increase of affinity |
seeded from UniProt:P25522 | ||||
mnmET250A |
T250A |
4-fold decrease in GTPase activity and 1.5-fold increase of affinity |
seeded from UniProt:P25522 | ||||
mnmET250S |
T250S |
1.8-fold decrease in GTPase activity and 1.5-fold increase of affinity |
seeded from UniProt:P25522 | ||||
mnmED270A |
D270A |
Does not affect GTP binding, but impairs hydrolase activity. Completely impairs tRNA modifying function |
seeded from UniProt:P25522 | ||||
mnmEL255D |
L255D |
1.5-fold decrease in affinity for GTP |
seeded from UniProt:P25522 | ||||
mnmER256A |
R256A |
2-fold decrease in GTPase activity and almost no change in affinity |
seeded from UniProt:P25522 | ||||
mnmEN226K |
N226K |
70-fold decrease in GTPase activity. 2-fold decrease of affinity for GTP |
seeded from UniProt:P25522 | ||||
mnmEG228A |
G228A |
Loss of GTP binding and hydrolase activity. Completely impairs tRNA modifying function |
seeded from UniProt:P25522 | ||||
mnmEC451S |
C451S |
No change in GTP binding and hydrolase activity. Does not affect association to the cell inner membrane. Completely impairs tRNA modifying function |
seeded from UniProt:P25522 | ||||
mnmER224A |
R224A |
1.5-fold decrease in GTPase activity and almost no change in affinity |
seeded from UniProt:P25522 | ||||
mnmET251A |
T251A |
92-fold decrease in GTPase activity and 59-fold increase of affinity |
seeded from UniProt:P25522 | ||||
mnmER275A |
R275A |
6-fold decrease in GTPase activity and 1.9-fold increase of affinity |
seeded from UniProt:P25522 | ||||
mnmEE282A |
E282A |
1900-fold decrease in GTPase activity |
seeded from UniProt:P25522 | ||||
mnmEE282Q |
E282Q |
370-fold decrease in GTPase activity |
seeded from UniProt:P25522 | ||||
mnmEN226A |
N226A |
100-fold decrease in GTPase activity. 5-fold decrease of affinity for GTP |
seeded from UniProt:P25522 | ||||
mnmER252K |
R252K |
2-fold decrease in GTPase activity and no change in affinity |
seeded from UniProt:P25522 | ||||
mnmED253A |
D253A |
9-fold decrease in GTPase activity and 13-fold increase of affinity |
seeded from UniProt:P25522 | ||||
ΔtrmE737::kan |
PMID:16738554 |
| |||||
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Notes
Genetic Interactions
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Interactor | Interaction | Allele | Score(s) | Reference(s) | Accessions | Notes |
---|---|---|---|---|---|---|
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Notes
Genetic Resources
See Help:Gene_resources for help entering information into the Genetic Resources table.
Resource | Resource Type | Source | Notes/Reference |
---|---|---|---|
Plasmid clone |
PMID:16769691 Status: Primer 1: Primer 2: | ||
Kohara Phage |
PMID:3038334 | ||
Kohara Phage |
PMID:3038334 | ||
Kohara Phage |
PMID:3038334 | ||
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
Database | Accession | Notes |
---|---|---|
EcoCyc:EG10997 |
Escherichia coli str. K-12 substr. MG1655 | |
EcoGene:EG10997 |
Escherichia coli str. K-12 substr. MG1655 | |
RegulonDB:ECK120000986 |
Escherichia coli str. K-12 substr. MG1655 | |
Escherichia coli str. K-12 substr. MG1655 | ||
EchoBASE:EB0990 |
Escherichia coli str. K-12 substr. MG1655 | |
ASAP:ABE-0012123 |
Escherichia coli str. K-12 substr. MG1655 | |
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Notes
Links
Name | URL | Comments |
---|---|---|
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Product(s)
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Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Standard name |
TrmE |
---|---|
Synonyms |
GTPase[1], B3706[3][1], MnmE[3][1], TrmE[3][1], ThdF[3][1], O454[3][1] , ECK3699, JW3684, thdF, trmE, b3706 |
Product description |
GTP-binding protein with a role in modification of tRNA[3][2] 5-methylaminomethyl-2-thiouridine modification at tRNA U34; cmnm(5) addition to tRNA-s(2)U34, forming (with subsequent or interdependent MnmG action) cmnm(5)s(2)U34-tRNA, an intermediate in mnm(5)s(2)U34-tRNA synthesis[4] |
EC number (for enzymes) |
|
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
---|---|---|---|---|---|---|---|---|
GO:0000287 |
magnesium ion binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
SP_KW:KW-0460 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0003924 |
GTPase activity |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
HAMAP:MF_00379 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0003924 |
GTPase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
InterPro:IPR004520 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0005525 |
GTP binding |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
HAMAP:MF_00379 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0005525 |
GTP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002917 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0005525 |
GTP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
InterPro:IPR004520 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0005525 |
GTP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
InterPro:IPR005225 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0005525 |
GTP binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
SP_KW:KW-0342 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0005737 |
cytoplasm |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
SP_KW:KW-0963 |
C |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0005737 |
cytoplasm |
GO_REF:0000023 |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0030955 |
potassium ion binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
SP_KW:KW-0630 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
GO:0046872 |
metal ion binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
SP_KW:KW-0479 |
F |
Seeded from EcoCyc (v14.0) |
complete | |
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Partner Type | Partner | Notes | References | Evidence |
---|---|---|---|---|
Protein |
aceE |
PMID:15690043 |
Experiment(s):EBI-890013, EBI-894976 | |
Protein |
rpsB |
PMID:15690043 |
Experiment(s):EBI-890013, EBI-894976 | |
Protein |
yliL |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
dcm |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
dsbA |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
hupA |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
lpdA |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
mdh |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
rplC |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
rplD |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
rplM |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
rplV |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
rpmG |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
rpsF |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
rpsG |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
rpsJ |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
rpsN |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
sapF |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
secA |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
pgaD |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
yidA |
PMID:15690043 |
Experiment(s):EBI-894976 | |
Protein |
dsbA |
PMID:19402753 |
LCMS(ID Probability):99.0 | |
Protein |
mdh |
PMID:19402753 |
LCMS(ID Probability):99.0 | |
Protein |
secA |
PMID:19402753 |
LCMS(ID Probability):99.0 MALDI(Z-score):14.201221 | |
Protein |
yidA |
PMID:19402753 |
LCMS(ID Probability):99.0 | |
Protein |
sapF |
PMID:19402753 |
LCMS(ID Probability):99.0 | |
Protein |
mnmG |
PMID:19402753 |
LCMS(ID Probability):99.0 MALDI(Z-score):27.178626 | |
Protein |
dcm |
PMID:19402753 |
LCMS(ID Probability):99.0 | |
Protein |
yliL |
PMID:19402753 |
LCMS(ID Probability):99.0 | |
Protein |
pgaD |
PMID:19402753 |
LCMS(ID Probability):99.0 | |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Compartment | Description | Evidence | Reference/Source | Notes |
---|---|---|---|---|
plasma membrane |
From EcoCyc[2] |
| ||
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Name | |
---|---|
Sequence |
MSDNDTIVAQ ATPPGRGGVG ILRISGFKAR EVAETVLGKL PKPRYADYLP FKDADGSVLD QGIALWFPGP NSFTGEDVLE LQGHGGPVIL DLLLKRILTI PGLRIARPGE FSERAFLNDK LDLAQAEAIA DLIDASSEQA ARSALNSLQG AFSARVNHLV EALTHLRIYV EAAIDFPDEE IDFLSDGKIE AQLNDVIADL DAVRAEARQG SLLREGMKVV IAGRPNAGKS SLLNALAGRE AAIVTDIAGT TRDVLREHIH IDGMPLHIID TAGLREASDE VERIGIERAW QEIEQADRVL FMVDGTTTDA VDPAEIWPEF IARLPAKLPI TVVRNKADIT GETLGMSEVN GHALIRLSAR TGEGVDVLRN HLKQSMGFDT NMEGGFLARR RHLQALEQAA EHLQQGKAQL LGAWAGELLA EELRLAQQNL SEITGEFTSD DLLGRIFSSF CIGK |
Length |
454 |
Mol. Wt |
49.232 kDa |
pI |
4.8 (calculated) |
Extinction coefficient |
26,470 - 26,595 (calc based on 3 Y, 4 W, and 1 C residues) |
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Domains/Motifs/Modification Sites
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
Structure
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Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Resource type | Source | Notes/Reference |
---|---|---|
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
Database | Accession | Notes |
---|---|---|
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
ASAP:ABE-0012123 |
Escherichia coli str. K-12 substr. MG1655 | |
Escherichia coli str. K-12 substr. MG1655 | ||
EcoCyc:EG10997 |
Escherichia coli str. K-12 substr. MG1655 | |
EcoGene:EG10997 |
Escherichia coli str. K-12 substr. MG1655 | |
Escherichia coli str. K-12 substr. MG1655 | ||
RegulonDB:ECK120000986 |
Escherichia coli str. K-12 substr. MG1655 | |
EchoBASE:EB0990 |
Escherichia coli str. K-12 substr. MG1655 | |
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Notes
Links
Name | URL | Comments |
---|---|---|
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Expression
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Overview
This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.
Cellular Levels
Molecule | Organism or Strain | Value | Units | Experimental Conditions | Assay used | Notes | Reference(s) |
---|---|---|---|---|---|---|---|
Protein |
Ecoli K-12 |
159.266+/-7.853 |
Molecules/cell |
|
Single Molecule Fluorescence |
PMID:20671182 | |
mRNA |
Ecoli K-12 |
0.77529+/-0.02581 |
Molecules/cell |
|
by FISH |
PMID:20671182 | |
Protein |
E. coli K-12 MG1655 |
1049 |
molecules/cell/generation |
|
Ribosome Profiling |
PMID: 24766808 | |
Protein |
E. coli K-12 MG1655 |
247 |
molecules/cell/generation |
|
Ribosome Profiling |
PMID: 24766808 | |
Protein |
E. coli K-12 MG1655 |
319 |
molecules/cell/generation |
|
Ribosome Profiling |
PMID: 24766808 | |
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Notes
Transcription and Transcriptional Regulation
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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.
|
File:.jpg |
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Notes
This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.
Translation and Regulation of Translation
<protect><gbrowseImage>
name=NC_000913:3884831..3884871
source=MG1655
type=Gene+DNA_+Protein
preset=Nterminus
</gbrowseImage>
This picture shows the sequence around the N-terminus.
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Notes
This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.
Turnover and Regulation of Turnover
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Notes
This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.
Experimental
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Mutations Affecting Expression
See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.
Allele Name | Mutation | Phenotype | Reference |
---|---|---|---|
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Expression Studies
See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.
Type | Reference | Notes |
---|---|---|
microarray |
NCBI GEO profiles for mnmE | |
microarray |
Summary of data for mnmE from multiple microarray studies | |
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Expression Resources
See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.
Resource Name | Resource Type | Description | Source | Notes |
---|---|---|---|---|
GFP Fusion |
Intergenic region (3884257..3884526) fused to gfpmut2. |
GFP fusion described in Zaslaver, et al. | ||
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Notes
Accessions Related to mnmE Expression
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
Database | Accession | Notes |
---|---|---|
EcoCyc:EG10997 |
Escherichia coli str. K-12 substr. MG1655 | |
EchoBASE:EB0990 |
Escherichia coli str. K-12 substr. MG1655 | |
EcoGene:EG10997 |
Escherichia coli str. K-12 substr. MG1655 | |
RegulonDB:ECK120000986 |
Escherichia coli str. K-12 substr. MG1655 | |
ASAP:ABE-0012123 |
Escherichia coli str. K-12 substr. MG1655 | |
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Notes
Links
Name | URL | Comments |
---|---|---|
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Evolution
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Homologs in Other Organisms
See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.
Organism | Homologs (Statistics) | Comments |
---|---|---|
Anopheles gambiae |
|
From Inparanoid:20070104 |
Apis mellifera |
|
From Inparanoid:20070104 |
Arabidopsis thaliana |
|
From Inparanoid:20070104 |
Bos taurus |
|
From Inparanoid:20070104 |
Caenorhabditis briggsae |
|
From Inparanoid:20070104 |
Caenorhabditis elegans |
|
From Inparanoid:20070104 |
Canis familiaris |
|
From Inparanoid:20070104 |
Ciona intestinalis |
|
From Inparanoid:20070104 |
Danio rerio |
|
From Inparanoid:20070104 |
Dictyostelium discoideum |
|
From Inparanoid:20070104 |
Drosophila melanogaster |
|
From Inparanoid:20070104 |
Homo sapiens |
|
From Inparanoid:20070104 |
Macaca mulatta |
|
From Inparanoid:20070104 |
Monodelphis domestica |
|
From Inparanoid:20070104 |
Mus musculus |
|
From Inparanoid:20070104 |
Oryza gramene |
|
From Inparanoid:20070104 |
Pan troglodytes |
|
From Inparanoid:20070104 |
Rattus norvegicus |
|
From Inparanoid:20070104 |
Saccharomyces cerevisiae |
|
From Inparanoid:20070104 |
Schizosaccharomyces pombe |
|
From Inparanoid:20070104 |
Takifugu rubripes |
|
From Inparanoid:20070104 |
Tetraodon nigroviridis |
|
From Inparanoid:20070104 |
Xenopus tropicalis |
|
From Inparanoid:20070104 |
Shigella flexneri |
THDF |
From SHIGELLACYC |
E. coli O157 |
THDF |
From ECOO157CYC |
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Do-It-Yourself Web Tools
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Notes
Families
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
Database | Accession | Notes |
---|---|---|
EcoCyc:EG10997 |
Escherichia coli str. K-12 substr. MG1655 | |
EcoGene:EG10997 |
Escherichia coli str. K-12 substr. MG1655 | |
RegulonDB:ECK120000986 |
Escherichia coli str. K-12 substr. MG1655 | |
EchoBASE:EB0990 |
Escherichia coli str. K-12 substr. MG1655 | |
ASAP:ABE-0012123 |
Escherichia coli str. K-12 substr. MG1655 | |
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Notes
Links
Name | URL | Comments |
---|---|---|
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References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Zaslaver, A et al. (2006) A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Nat. Methods 3 623-8 PubMed
Categories
- Genes in OpenBioSystems with Promoter Fusions
- Genes with homologs in Anopheles gambiae
- Genes with homologs in Apis mellifera
- Genes with homologs in Arabidopsis thaliana
- Genes with homologs in Bos taurus
- Genes with homologs in Caenorhabditis briggsae
- Genes with homologs in Caenorhabditis elegans
- Genes with homologs in Canis familiaris
- Genes with homologs in Ciona intestinalis
- Genes with homologs in Danio rerio
- Genes with homologs in Dictyostelium discoideum
- Genes with homologs in Drosophila melanogaster
- Genes with homologs in Homo sapiens
- Genes with homologs in Macaca mulatta
- Genes with homologs in Monodelphis domestica
- Genes with homologs in Mus musculus
- Genes with homologs in Oryza gramene
- Genes with homologs in Pan troglodytes
- Genes with homologs in Rattus norvegicus
- Genes with homologs in Saccharomyces cerevisiae
- Genes with homologs in Schizosaccharomyces pombe
- Genes with homologs in Takifugu rubripes
- Genes with homologs in Tetraodon nigroviridis
- Genes with homologs in Xenopus tropicalis
- Genes with homologs in Shigella flexneri
- Genes with homologs in E. coli O157