{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

On One Page

Quickview |

Gene |

Product(s) |

Expression|

Evolution |

References |

Quickview

[back to top]

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Standard Name	yddE
Gene Synonym(s)	ECK1458, b1464, JW1459^[1], JW1459
Product Desc.	conserved protein^[2]^[3] Function unknown^[4]
Product Synonyms(s)	conserved protein^[1], B1464^[2]^[1], YddE^[2]^[1] , ECK1458, JW1459, b1464
Function from GO	<GO_nr />
Knock-Out Phenotype
Regulation/Expression	transcription unit(s): yddE^[2]
Regulation/Activity
Quick Links
edit table

</protect> See Help:Quickview for help with entering information in the Quickview table. <protect></protect>

Notes

[back to top]

Structural Genomics target No. 87 (http://afmb.cnrs-mrs.fr/article171.html).^[4]

Gene

[back to top]

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css> <protect>

Nomenclature

[back to top]

See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name	yddE
Mnemonic	Systematic nomenclature
Synonyms	ECK1458, b1464, JW1459^[1], JW1459
edit table

</protect>

Notes

Location(s) and DNA Sequence

[back to top]

<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain	Map location	Genome coordinates	Genome browsers	Sequence links
MG1655	33.04 minutes	MG1655: 1533882..1532989 <gbrowseImage> name=NC_000913:1532989..1533882 source=MG1655 preset=GeneLocation </gbrowseImage>	EcoCyc GBrowse(MG1655)	FASTA Dump EcoCyc Sequence Dump
BW2952		NC_012759: 1425048..1425941 <gbrowseImage> name=NC_012759:1425048..1425941 source=BW2952 preset=GeneLocation </gbrowseImage>	GBrowse (BW2952)	FASTA Dump
W3110		W3110: 1537572..1536679 <gbrowseImage> name=NC_007779:1536679..1537572 source=W3110 preset=GeneLocation </gbrowseImage>	GBrowse(W3110)	FASTA Dump
DH10B		DH10B: 1624477..1623584 <gbrowseImage> name=NC_010473:1623584..1624477 source=DH10B preset=GeneLocation </gbrowseImage>	GBrowse(DH10B)	FASTA Dump
edit table

</protect>

Notes

Sequence Features

[back to top]

See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type	Strain	Genomic Location	Evidence	Reference	Notes
edit table

Notes

Alleles and Phenotypes

[back to top]

See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele	Nt change(s)	AA change(s)	Reference	Availability	Comments
ΔyddE (Keio:JW1459)	deletion	deletion	PMID:16738554	Shigen CGSC9270^[5]
zdd-235::Tn10	Insertion at 1,533,652 bp in MG1655 (NC_000913)		adapted from Nichols et al.^[6]	CAG18461 = CGSC7378^[5]	Synonyms: zdc-235::Tn10
ΔyddE757::kan			PMID:16738554	CGSC:104202
edit table

Notes

Genetic Interactions

[back to top]

Interactor	Interaction	Allele	Score(s)	Reference(s)	Accessions	Notes
edit table

</protect>

Notes

Genetic Resources

[back to top]

See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource	Resource Type	Source	Notes/Reference
JW1459	Plasmid clone	Shigen	PMID:16769691 Status:Clone OK Primer 1:GCCAAACCGCAGGTGTACCACGT Primer 2:CCGAGTTCAATTGCCCATTCGGC
6D4	Kohara Phage	Genobase	PMID:3038334
1G4	Kohara Phage	Genobase	PMID:3038334
trg-2::Tn10	Linked marker	CAG12026 = CGSC7376^[5]	est. P1 cotransduction: 19% ^[6]
zdi-925::Tn10	Linked marker	CAG12151 = CGSC7385^[5]	est. P1 cotransduction: % ^[6] Synonyms:zdh-925::Tn10
edit table

Notes

Accessions in Other Databases

[back to top]

See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc	EcoCyc:EG11825	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG11825	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001757	Escherichia coli str. K-12 substr. MG1655
NCBI (EcoliWiki Page)	GeneID:944782	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1772	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0004886	Escherichia coli str. K-12 substr. MG1655
edit table

Notes

Links

[back to top]

Name	URL	Comments
edit table

Product(s)

[back to top]

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name	YddE
Synonyms	conserved protein^[1], B1464^[2]^[1], YddE^[2]^[1] , ECK1458, JW1459, b1464
Product description	conserved protein^[2]^[3] Function unknown^[4]
EC number (for enzymes)
edit table

Notes

Function

[back to top]

<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0003824	catalytic activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003719	F	Seeded from EcoCyc (v14.0)	complete
	GO:0009058	biosynthetic process	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003719	P	Seeded from EcoCyc (v14.0)	complete
	GO:0016853	isomerase activity	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0413	F	Seeded from EcoCyc (v14.0)	complete
edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	References	Evidence
Protein	yfhM	PMID:16606699	Experiment(s):EBI-1139910
Protein	mfd	PMID:16606699	Experiment(s):EBI-1139910
Protein	gltB	PMID:16606699	Experiment(s):EBI-1139910
Protein	rpoB	PMID:16606699	Experiment(s):EBI-1139910
Protein	nadE	PMID:16606699	Experiment(s):EBI-1139910
edit table

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
edit table

Notes

Structure and Physical Properties

[back to top]

<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MKPQVYHVDA FTSQPFRGNS AGVVFPADNL SEAQMQLIAR ELGHSETAFL LHSDDSDVRI RYFTPTVEVP ICGHATVAAH YVRAKVLGLG NCTIWQTSLA GKHRVTIEKH NDDYRISLEQ GTPGFEPPLE GETRAAIINA LHLTEDDILP GLPIQVATTG HSKVMIPLKP EVDIDALSPD LNALTAISKK IGCNGFFPFQ IRPGKNETDG RMFSPAIGIV EDPVTGNANG PMGAWLVHHN VLPHDGNVLR VKGHQGRALG RDGMIEVTVT IRDNQPEKVT ISGTAVILFH AEWAIEL
Length	297
Mol. Wt	32.318 kDa
pI	6.3 (calculated)
Extinction coefficient	22,460 - 22,835 (calc based on 4 Y, 3 W, and 3 C residues)
edit table

Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes	References
Domain	8..291	PF02567 Phenazine biosynthesis-like protein		PMID:19920124
edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yddE taxon=562,83333 </beststructure>

Models

View models at:

edit table

</protect>

Structure figures

</protect>

Notes

Gene Product Resources

[back to top]

See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
edit table

Notes

Accessions in Other Databases

[back to top]

See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:16129423	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:944782	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0004886	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P37757	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:EG11825	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG11825	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:944782	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001757	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1772	Escherichia coli str. K-12 substr. MG1655
edit table

Notes

Links

[back to top]

Name	URL	Comments
edit table

Expression

[back to top]

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Cellular Levels

[back to top]

See Help:Cellular levels

Molecule	Organism or Strain	Value	Units	Experimental Conditions	Assay used	Reference(s)
Protein	E. coli K-12 MG1655	234	molecules/cell/generation	Medium: MOPS Complete Temperature (°C): 37 Doubling time (min): *Growth phase: OD: other:	Ribosome Profiling	PMID: 24766808
Protein	E. coli K-12 MG1655	195	molecules/cell/generation	Medium: MOPS Minimal Temperature (°C): 37 Doubling time (min): *Growth phase: OD: other:	Ribosome Profiling	PMID: 24766808
Protein	E. coli K-12 MG1655	174	molecules/cell/generation	Medium: MOPS Complete without Methionine Temperature (°C): 37 Doubling time (min): *Growth phase: OD: other:	Ribosome Profiling	PMID: 24766808
edit table

Notes

Transcription and Transcriptional Regulation

[back to top]

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)
yddE
edit table

Figure courtesy of RegulonDB

</protect>

Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

[back to top]

<protect><gbrowseImage> name=NC_000913:1533862..1533902 source=MG1655 flip=1 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

</protect>

Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

</protect>

Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

[back to top]

<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name	Mutation	Phenotype	Reference
edit table

Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type	Reference	Notes
microarray	GEO Profiles:b1464 (EcoliWiki Page)	NCBI GEO profiles for yddE
microarray	GenExpDB:b1464 (EcoliWiki Page)	Summary of data for yddE from multiple microarray studies
edit table

Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name	Resource Type	Description	Source	Notes
	GFP Fusion	Intergenic region (1533807..1534015) fused to gfpmut2.	OpenBioSystems	GFP fusion described in Zaslaver, et al. Plate:109-AZ16; Well:B9^[7]
edit table

Notes

Accessions Related to yddE Expression

[back to top]

See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc	EcoCyc:EG11825	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1772	Escherichia coli str. K-12 substr. MG1655
EcoliGenExpDB (EcoliWiki Page)	EcoliGenExpDB:b1464
EcoGene	EcoGene:EG11825	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001757	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0004886	Escherichia coli str. K-12 substr. MG1655
edit table

Notes

Links

[back to top]

Name	URL	Comments
edit table

Evolution

[back to top]

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Homologs in Other Organisms

[back to top]

See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism	Homologs (Statistics)	Comments
Anopheles gambiae	ENSANGP00000013785 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Arabidopsis thaliana	AT1G03210 (score: 1.000; bootstrap: 100%) AT4G02860 (score: 0.659) AT4G02850 (score: 0.591)	From Inparanoid:20070104
Bos taurus	ENSBTAP00000019038 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Caenorhabditis briggsae	WBGene00026221 (score: 1.000; bootstrap: 100%) WBGene00026222 (score: 0.676)	From Inparanoid:20070104
Caenorhabditis elegans	WBGene00011416 (score: 1.000; bootstrap: 100%) WBGene00011419 (score: 1.000; bootstrap: 100%) WBGene00011420 (score: 0.704) WBGene00011417 (score: 0.704)	From Inparanoid:20070104
Canis familiaris	ENSCAFP00000020022 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Ciona intestinalis	ENSCINP00000003381 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Danio rerio	ZDB-GENE-050522-217 (score: 1.000; bootstrap: 100%) ZDB-CDNA-050522-217 (score: 1.000; bootstrap: 100%) ZDB-CDNA-040808-19 (score: 0.809) ZDB-GENE-040808-16 (score: 0.809) ZDB-CDNA-050417-457 (score: 0.413) ZDB-GENE-050417-456 (score: 0.413)	From Inparanoid:20070104
Gallus gallus	ENSGALP00000006258 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Homo sapiens	ENSP00000308466 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Macaca mulatta	ENSMMUP00000019823 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Mus musculus	MGI:1915621 (score: 1.000; bootstrap: 100%) MGI:1914557 (score: 0.904)	From Inparanoid:20070104
Pan troglodytes	ENSPTRP00000004407 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Rattus norvegicus	ENSRNOP00000000434 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Saccharomyces cerevisiae	YHR029C (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Schizosaccharomyces pombe	SPBPB21E77 (score: 1.000; bootstrap: 100%) SPAC1866 (score: 0.059)	From Inparanoid:20070104
Takifugu rubripes	NEWSINFRUP00000172249 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Tetraodon nigroviridis	GSTENP00025785001 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Xenopus tropicalis	ENSXETP00000009573 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
E. coli O157	YDDE	From ECOO157CYC
edit table

Do-It-Yourself Web Tools

Notes

Families

[back to top]

See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
Pfam (EcoliWiki Page)	PF02567 Phenazine biosynthesis-like protein
Panther (EcoliWiki Page)	PTHR13774:SF12
Superfamily (EcoliWiki Page)	SUPERFAMILY:54506
EcoCyc	EcoCyc:EG11825	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG11825	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001757	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1772	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0004886	Escherichia coli str. K-12 substr. MG1655
edit table

Notes

Links

[back to top]

Name	URL	Comments
edit table

References

[back to top]

See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^4.0 ^4.1 ^4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 ^5.2 ^5.3 CGSC: The Coli Genetics Stock Center
↑ ^6.0 ^6.1 ^6.2 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
↑ Zaslaver, A et al. (2006) A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Nat. Methods 3 623-8 PubMed

yddE:On One Page

Quickview

Notes

Gene

Nomenclature

Notes

Location(s) and DNA Sequence

Notes

Sequence Features

Notes

Alleles and Phenotypes

Notes

Genetic Interactions

Notes

Genetic Resources

Notes

Accessions in Other Databases

Notes

Links

Product(s)

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

Expression

Overview

Cellular Levels

Notes

Transcription and Transcriptional Regulation

Notes

Translation and Regulation of Translation

Notes

Turnover and Regulation of Turnover

Notes

Experimental

Notes

Accessions Related to yddE Expression

Notes

Links

Evolution

Homologs in Other Organisms

Do-It-Yourself Web Tools

Notes

Families

Notes

Links

References

Categories

Navigation menu

Search