gnd:Gene
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Location(s) and DNA Sequence | Sequence Features | Alleles and Phenotypes | Genetic Interactions | Genetic Resources | Accessions | Links | References | Suggestions |
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Nomenclature
See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.
| Standard name |
gnd |
|---|---|
| Mnemonic |
Gluconate-P dehydrogenase |
| Synonyms |
ECK2024, b2029, JW2011[1], JW2011 |
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Notes
Location(s) and DNA Sequence
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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.
| Strain | Map location | Genome coordinates | Genome browsers | Sequence links |
|---|---|---|---|---|
|
MG1655 |
45.22 minutes, 45.22 minutes |
MG1655: 2099292..2097886 |
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NC_012967: 2031269..2029863 |
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NC_012759: 1990369..1991775 |
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W3110 |
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W3110: 2103405..2101999 |
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DH10B: 2190300..2188894 |
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Notes
Sequence Features
See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.
| Feature Type | Strain | Genomic Location | Evidence | Reference | Notes |
|---|---|---|---|---|---|
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Notes
Alleles and Phenotypes
See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.
| Allele | Nt change(s) | AA change(s) | Phenotype: Type | Phenotype: Description | Reference | Availability | Comments |
|---|---|---|---|---|---|---|---|
|
gndL325Q |
L325Q |
(in strain: ECOR 69) |
Strain variation; seeded from UniProt:P00350 | ||||
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gndI330S |
I330S |
(in strain: ECOR 10) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndS422A |
S422A |
(in strain: ECOR 10, ECOR 65, ECOR 68, ECOR 69 and ECOR 70) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndV52D |
V52D |
(in strain: ECOR 10) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndY55F |
Y55F |
(in strain: ECOR 10) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndIGT123YRY |
IGT123YRY |
(in strain: O7:K1 / VW187) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndV170F |
V170F |
(in strain: ECOR 10) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndA117S |
A117S |
(in strain: ECOR 70) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndD350A |
D350A |
(in strain: ECOR 10 and ECOR 69) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndQ369R |
Q369R |
(in strain: ECOR 10) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndD313N |
D313N |
(in strain: ECOR 67) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndA315G |
A315G |
(in strain: ECOR 70) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndA308G |
A308G |
(in strain: ECOR 68) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndD294E |
D294E |
(in strain: ECOR 70) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndT211S |
T211S |
(in strain: ECOR 10 and ECOR 69) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndA216T |
A216T |
(in strain: ECOR 67) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndA175S |
A175S |
(in strain: ECOR 45) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndN209S |
N209S |
(in strain: ECOR 68) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndF32Y |
F32Y |
(in strain: ECOR 70) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndN102K |
N102K |
(in strain: ECOR 65) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndT39Q |
T39Q |
(in strain: O7:K1 / VW187) |
Strain variation; seeded from UniProt:P00350 | ||||
|
gndS2L |
S2L |
(in strain: ECOR 70) |
Strain variation; seeded from UniProt:P00350 | ||||
|
Δgnd (Keio:JW2011) |
deletion |
deletion |
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Δgnd::kan |
deletion |
Biolog:respiration |
unable to respire Acetate |
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gnd-1 |
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Δgnd-727::kan |
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Notes
Genetic Interactions
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| Interactor | Interaction | Allele | Score(s) | Reference(s) | Accessions | Notes |
|---|---|---|---|---|---|---|
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Notes
Genetic Resources
See Help:Gene_resources for help entering information into the Genetic Resources table.
| Resource | Resource Type | Source | Notes/Reference |
|---|---|---|---|
|
JW2011 |
Plasmid clone |
Status:Clone OK Primer 1:GCCTCCAAGCAACAGATCGGCGT Primer 2:CCATCCAGCCATTCGGTATGGAA | |
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Kohara Phage |
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zef-3129::Tn10 |
Linked marker |
est. P1 cotransduction: 60% [7] | |
|
Linked marker |
est. P1 cotransduction: % [7] | ||
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
| Name | URL | Comments |
|---|---|---|
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References
See Help:References for how to manage references in EcoliWiki.
- ↑ Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 Baba, T et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2 2006.0008 PubMed
- ↑ 3.0 3.1 3.2 CGSC: The Coli Genetics Stock Center
- ↑ Ito, M et al. (2005) Functional analysis of 1440 Escherichia coli genes using the combination of knock-out library and phenotype microarrays. Metab. Eng. 7 318-27 PubMed
- ↑ Kitagawa, M et al. (2005) Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. DNA Res. 12 291-9 PubMed
- ↑ Kohara, Y et al. (1987) The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50 495-508 PubMed
- ↑ 7.0 7.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
