gltA:Gene Product(s)

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

GltA

Synonyms

citrate synthase[1], B0720[2][1], IcdB[2][1], GltA[2][1]

Product description

citrate synthase[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki. See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005624

membrane fraction

PMID:16858726[4]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0003824

catalytic activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0021

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0004108

citrate (Si)-synthase activity

GO_REF:0000002
GO_REF:0000003

IEA: Inferred from Electronic Annotation

InterPro:IPR010953
EC:2.3.3.1

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005737

cytoplasm

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010953

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0006099

tricarboxylic acid cycle

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0816

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002020

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0006099

tricarboxylic acid cycle

PMID:13367004[6]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc 11.1[3].

complete

GO:0009061

anaerobic respiration

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0003878

ATP citrate synthase activity

F

required field missing

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

matC

PMID:16606699[7]

Experiment(s):EBI-1137791

Protein

groL

PMID:16606699[7]

Experiment(s):EBI-1137791

Protein

nadE

PMID:16606699[7]

Experiment(s):EBI-1137791

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Notes

Localization

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Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MADTKAKLTL NGDTAVELDV LKGTLGQDVI DIRTLGSKGV FTFDPGFTST ASCESKITFI
DGDEGILLHR GFPIDQLATD SNYLEVCYIL LNGEKPTQEQ YDEFKTTVTR HTMIHEQITR
LFHAFRRDSH PMAVMCGITG ALAAFYHDSL DVNNPRHREI AAFRLLSKMP TMAAMCYKYS
IGQPFVYPRN DLSYAGNFLN MMFSTPCEPY EVNPILERAM DRILILHADH EQNASTSTVR
TAGSSGANPF ACIAAGIASL WGPAHGGANE AALKMLEEIS SVKHIPEFVR RAKDKNDSFR
LMGFGHRVYK NYDPRATVMR ETCHEVLKEL GTKDDLLEVA MELENIALND PYFIEKKLYP
NVDFYSGIIL KAMGIPSSMF TVIFAMARTV GWIAHWSEMH SDGMKIARPR QLYTGYEKRD
FKSDIKR
Mol. Wt

48.01 kDa (calc) [2]

pI

6.62[2]

Extinction coefficient

40340 - 41215 (calc based on 16 Y, 3 W, and 7 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes
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Structure

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Structures

<beststructure>gltA 562</beststructure>

Models

View models at:

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Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:CITSYN-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0ABH7

PFAM (EcoliWiki Page)

PFAM:PF00285

RefSeq (EcoliWiki Page)

RefSeq:NP_415248

ModBase (EcoliWiki Page)

ModBase:P0ABH7

PDB (EcoliWiki Page)

PDB:1K3P


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Notes

Links

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Name URL Comments
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References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. ↑ DAVIS, BD & GILVARG, C (1956) The role of the tricarboxylic acid cycle in acetate oxidation in Escherichia coli. J. Biol. Chem. 222 307-19 PubMed
  7. ↑ 7.0 7.1 7.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed


Categories

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