galE:Gene Product(s)

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

GalE product

Synonyms

UDP-galactose-4-epimerase product[1], B0759 product[2][1], GalD product[2][1], GalE product[2][1]

Product description

UDP-glucose 4-epimerase monomer[2][3];

Component of ; UDP-glucose 4-epimerase[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001509

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0003978

UDP-glucose 4-epimerase activity

GO_REF:0000002
GO_REF:0000003

IEA: Inferred from Electronic Annotation

InterPro:IPR005886
EC:5.1.3.2

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0005975

carbohydrate metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0119

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009242

colanic acid biosynthetic process

PMID:6090411[5]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc 11.1[3].

complete

GO:0016052

carbohydrate catabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009435

NAD biosynthetic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

Under review

GO:0009269

response to desiccation

P

Seeded from EcoCyc 11.1[3].

See discussion page.

required field missing

Under review

GO:0042603

capsule

C

Seeded from EcoCyc 11.1[3].

GalE is not located in the capsule.

required field missing

GO:0006012

galactose metabolic process

PMID:13914787[6]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006012

galactose metabolic process

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR005886
SP_KW:KW-0299

P

Seeded from EcoCyc 12.5 [4]

complete

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Interactions

Partner Type Partner Notes

Protein

Subunits of UDP-glucose 4-epimerase

could be indirect

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Notes

Localization

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc 

MRVLVTGGSG YIGSHTCVQL LQNGHDVIIL DNLCNSKRSV LPVIERLGGK HPTFVEGDIR
NEALMTEILH DHAIDTVIHF AGLKAVGESV QKPLEYYDNN VNGTLRLISA MRAANVKNFI
FSSSATVYGD QPKIPYVESF PTGTPQSPYG KSKLMVEQIL TDLQKAQPDW SIALLRYFNP
VGAHPSGDMG EDPQGIPNNL MPYIAQVAVG RRDSLAIFGN DYPTEDGTGV RDYIHVMDLA
DGHVVAMEKL ANKPGVHIYN LGAGVGNSVL DVVNAFSKAC GKPVNYHFAP RREGDLPAYW
ADASKADREL NWRVTRTLDE MAQDTWHWQS RHPQGYPD
Mol. Wt

37.27 kDa (calc) [2]

pI

6.28[2]

Extinction coefficient

48360 - 48735 (calc based on 14 Y, 5 W, and 3 C residues)

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Domains/Motifs/Modification Sites

Type Residues Description Notes
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Structure

Structures

<beststructure>galE 562</beststructure>

Models

View models at:

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Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:UDPGLUCEPIM-MONOMER

UniProt (EcoliWiki Page)

UniProt:P09147

PFAM (EcoliWiki Page)

PFAM:PF01370

RefSeq (EcoliWiki Page)

RefSeq:NP_415280

ModBase (EcoliWiki Page)

ModBase:P09147

PDB (EcoliWiki Page)

PDB:1A9Y


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 4.3 4.4 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. ↑ Trisler, P & Gottesman, S (1984) lon transcriptional regulation of genes necessary for capsular polysaccharide synthesis in Escherichia coli K-12. J. Bacteriol. 160 184-91 PubMed
  6. ↑ SOFFER, RL (1961) Enzymatic expression of genetic units of function concerned with galactose metabolism in Escherichia coli. J. Bacteriol. 82 471-8 PubMed


Categories

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