infB:Gene Product(s)

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

InfB

Synonyms

fused protein chain initiation factor 2, IF2: membrane protein[1], conserved protein[1], B3168[2][1], SsyG[2][1], InfB[2][1], IF2[2][1]

Product description

protein chain initiation factor IF-2[2][3]

Protein chain initiation factor IF2[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR009061
SP_KW:KW-0547

F

Seeded from EcoCyc [5]

complete

GO:0003743

translation initiation factor activity

PMID:9428651[6]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 12.5 [7]

complete

GO:0003924

GTPase activity

GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000795
HAMAP:MF_00100

F

Seeded from EcoCyc 12.5 [7]

complete

GO:0005525

GTP binding

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR000178
InterPro:IPR000795
InterPro:IPR004161
InterPro:IPR005225
SP_KW:KW-0342

F

Seeded from EcoCyc [5]

complete

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000178

C

Seeded from EcoCyc [5]

complete

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc 12.5 [7]

complete

GO:0006412

translation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0648

P

Seeded from EcoCyc [5]

complete

GO:0006413

translational initiation

GO_REF:0000002
GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000178
InterPro:IPR006847
HAMAP:MF_00100

P

Seeded from EcoCyc 12.5 [7]

complete

GO:0043022

ribosome binding

F

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

ribD

PMID:15690043[8]

Experiment(s):EBI-889882

Protein

rplC

PMID:15690043[8]

Experiment(s):EBI-889882, EBI-894820

Protein

rplM

PMID:15690043[8]

Experiment(s):EBI-889882

Protein

metN

PMID:15690043[8]

Experiment(s):EBI-894820

Protein

dnaK

PMID:15690043[8]

Experiment(s):EBI-894820

Protein

grpE

PMID:15690043[8]

Experiment(s):EBI-894820

Protein

phoA

PMID:15690043[8]

Experiment(s):EBI-894820

Protein

rpmG

PMID:15690043[8]

Experiment(s):EBI-894820

Protein

adhP

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

phoA

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

ygfZ

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

rpsE

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

rhlE

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

rplJ

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

arpA

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

uup

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

greA

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

yedJ

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

ybiB

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

mhpR

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

artM

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

rplF

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

ebgC

PMID:16606699[9]

Experiment(s):EBI-1144996

Protein

fliJ

PMID:16606699[9]

Experiment(s):EBI-1144996
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MTDVTIKTLA AERQTSVERL VQQFADAGIR KSADDSVSAQ EKQTLIDHLN QKNSGPDKLT
LQRKTRSTLN IPGTGGKSKS VQIEVRKKRT FVKRDPQEAE RLAAEEQAQR EAEEQARREA
EESAKREAQQ KAEREAAEQA KREAAEQAKR EAAEKDKVSN QQDDMTKNAQ AEKARREQEA
AELKRKAEEE ARRKLEEEAR RVAEEARRMA EENKWTDNAE PTEDSSDYHV TTSQHARQAE
DESDREVEGG RGRGRNAKAA RPKKGNKHAE SKADREEARA AVRGGKGGKR KGSSLQQGFQ
KPAQAVNRDV VIGETITVGE LANKMAVKGS QVIKAMMKLG AMATINQVID QETAQLVAEE
MGHKVILRRE NELEEAVMSD RDTGAAAEPR APVVTIMGHV DHGKTSLLDY IRSTKVASGE
AGGITQHIGA YHVETENGMI TFLDTPGHAA FTSMRARGAQ ATDIVVLVVA ADDGVMPQTI
EAIQHAKAAQ VPVVVAVNKI DKPEADPDRV KNELSQYGIL PEEWGGESQF VHVSAKAGTG
IDELLDAILL QAEVLELKAV RKGMASGAVI ESFLDKGRGP VATVLVREGT LHKGDIVLCG
FEYGRVRAMR NELGQEVLEA GPSIPVEILG LSGVPAAGDE VTVVRDEKKA REVALYRQGK
FREVKLARQQ KSKLENMFAN MTEGEVHEVN IVLKADVQGS VEAISDSLLK LSTDEVKVKI
IGSGVGGITE TDATLAAASN AILVGFNVRA DASARKVIEA ESLDLRYYSV IYNLIDEVKA
AMSGMLSPEL KQQIIGLAEV RDVFKSPKFG AIAGCMVTEG VVKRHNPIRV LRDNVVIYEG
ELESLRRFKD DVNEVRNGME CGIGVKNYND VRTGDVIEVF EIIEIQRTIA
Length

890

Mol. Wt

97.348 kDa

pI

6.0 (calculated)

Extinction coefficient

27,390 - 27,765 (calc based on 11 Y, 2 W, and 3 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References
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<motif_map/>

Structure
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Structures

<beststructure> gene=infB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10505-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0A705

PFAM (EcoliWiki Page)

PFAM:PF04760

RefSeq (EcoliWiki Page)

RefSeq:NP_417637


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ Steffensen, SA et al. (1997) E. coli translation initiation factor IF2--an extremely conserved protein. Comparative sequence analysis of the infB gene in clinical isolates of E. coli. FEBS Lett 419 281-4 PubMed
  7. ↑ 7.0 7.1 7.2 7.3 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  8. ↑ 8.0 8.1 8.2 8.3 8.4 8.5 8.6 8.7 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  9. ↑ 9.00 9.01 9.02 9.03 9.04 9.05 9.06 9.07 9.08 9.09 9.10 9.11 9.12 9.13 9.14 9.15 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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