galE:Gene Product(s)
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
GalE |
|---|---|
| Synonyms |
UDP-galactose-4-epimerase[1], B0759[2][1], GalD[2][1], GalE[2][1] |
| Product description |
UDP-glucose 4-epimerase[2][3]; Component of UDP-glucose 4-epimerase[2][3] UDP-galactose 4-epimerase; hexose-1-phosphate uridylyltransferase[4] |
| EC number (for enzymes) | |
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0003978 |
UDP-glucose 4-epimerase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [6] |
complete | |||
| GO:0006012 |
galactose metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0016853 |
isomerase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0044237 |
cellular metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0050662 |
coenzyme binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0005737 |
cytoplasm |
C |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc [6] |
complete | |||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc [6] |
complete | |||
| GO:0009242 |
colanic acid biosynthetic process |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 11.1[3]. |
complete | |||
| GO:0016052 |
carbohydrate catabolic process |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0009435 |
NAD biosynthetic process |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
|
Under review |
GO:0009269 |
response to desiccation |
P |
Seeded from EcoCyc 11.1[3]. See discussion page. |
required field missing | |||
|
Under review |
GO:0042603 |
capsule |
C |
Seeded from EcoCyc 11.1[3]. GalE is not located in the capsule. |
required field missing | |||
| GO:0006012 |
galactose metabolic process |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| GO:0005975 |
carbohydrate metabolic process |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| GO:0006012 |
galactose metabolic process |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc 12.5 [5] |
complete | |||
| GO:0016052 |
carbohydrate catabolic process |
IGI: Inferred from Genetic Interaction |
P |
complete | ||||
| GO:0016857 |
racemase and epimerase activity, acting on carbohydrates and derivatives |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0006012 |
galactose metabolic process |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
complete | ||||
| GO:0005975 |
carbohydrate metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc [6] |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of UDP-glucose 4-epimerase |
could be indirect |
||
|
Protein |
rsuA |
Experiment(s):EBI-1137880 | ||
|
Protein |
yfcH |
Experiment(s):EBI-1137880 | ||
|
Protein |
nadE |
Experiment(s):EBI-1137880 | ||
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MRVLVTGGSG YIGSHTCVQL LQNGHDVIIL DNLCNSKRSV LPVIERLGGK HPTFVEGDIR NEALMTEILH DHAIDTVIHF AGLKAVGESV QKPLEYYDNN VNGTLRLISA MRAANVKNFI FSSSATVYGD QPKIPYVESF PTGTPQSPYG KSKLMVEQIL TDLQKAQPDW SIALLRYFNP VGAHPSGDMG EDPQGIPNNL MPYIAQVAVG RRDSLAIFGN DYPTEDGTGV RDYIHVMDLA DGHVVAMEKL ANKPGVHIYN LGAGVGNSVL DVVNAFSKAC GKPVNYHFAP RREGDLPAYW ADASKADREL NWRVTRTLDE MAQDTWHWQS RHPQGYPD |
|---|---|
| Mol. Wt |
37.27 kDa (calc) [2] |
| pI |
6.28[2] |
| Extinction coefficient |
48360 - 48735 (calc based on 14 Y, 5 W, and 3 C residues) |
| edit table |
Domains/Motifs/Modification Sites
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
| Type | Residues | Description | Notes |
|---|---|---|---|
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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
| Structures |
<beststructure>galE 562</beststructure> |
|---|---|
| Models |
View models at: |
| edit table |
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
| ||
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 6.0 6.1 6.2 6.3 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
- ↑ Trisler, P & Gottesman, S (1984) lon transcriptional regulation of genes necessary for capsular polysaccharide synthesis in Escherichia coli K-12. J. Bacteriol. 160 184-91 PubMed
- ↑ 9.0 9.1 9.2 Fietta, A et al. (1981) R-factor-mediated suppression of the galactose-sensitive phenotype of Escherichia coli K-12 galE Mutants. Plasmid 6 78-85 PubMed
- ↑ SOFFER, RL (1961) Enzymatic expression of genetic units of function concerned with galactose metabolism in Escherichia coli. J. Bacteriol. 82 471-8 PubMed
- ↑ 11.0 11.1 11.2 Vorgias, CE et al. () Overexpression and purification of the galactose operon enzymes from Escherichia coli. Protein Expr. Purif. 2 330-8 PubMed
- ↑ 12.0 12.1 12.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
Categories
- GO:0003824 ! catalytic activity
- GO:0003978 ! UDP-glucose 4-epimerase activity
- GO:0006012 ! galactose metabolic process
- GO:0016853 ! isomerase activity
- GO:0044237 ! cellular metabolic process
- GO:0050662 ! coenzyme binding
- GO:0005737 ! cytoplasm
- GO:0005488 ! binding
- GO:0005829 ! cytosol
- GO:0009242 ! colanic acid biosynthetic process
- GO:0016052 ! carbohydrate catabolic process
- GO:0009435 ! NAD biosynthetic process
- GO:0009269 ! response to desiccation
- GO:0042603 ! capsule
- GO:0005975 ! carbohydrate metabolic process
- GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
- Proteins
- GO:0042280 ! cell surface antigen activity, host-interacting
- GO:0030113 ! capsule (sensu Bacteria)
- Complex:UDP-glucose 4-epimerase
- Products with structures in PDB