Phage lambda A:On One Page: Difference between revisions

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Revision as of 13:41, 26 July 2007

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

Quickview

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Standard Name

Phage lambda A

Gene Synonym(s)

A, lambdap02

Product Desc.

DNA packaging protein, Component of terminase

Product Synonyms(s)

A, lambdap02

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression
Regulation/Activity
Quick Links



        

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Notes

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Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

Phage lambda A

Mnemonic
Synonyms

A, lambdap02

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Notes

Location(s) and DNA Sequence

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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

NC_001416

NC_001416: 711..2636
<gbrowseImage> name=NC_001416:711..2636 source=bacteriophage_lambda preset=GeneLocation </gbrowseImage>

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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes
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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments
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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes
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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

A

Synonyms

A, lambdap02

Product description

DNA packaging protein, Component of terminase

EC number (for enzymes)


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Notes

Function

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Gene Ontology See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019028

viral capsid

PMID:5227665[1]

IMP: Inferred from Mutant Phenotype

C

Essential for lambda head production

complete

GO:0043493

phage terminase complex

PMID:6264675[2]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0019073

viral DNA genome packaging

PMID:860404[3]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0098036

viral DNA genome packaging, 3' extended cos packaging

PMID:7813452[4]

IDA: Inferred from Direct Assay

P

complete

GO:0016887

ATPase activity

PMID:17870092[5]

IMP: Inferred from Mutant Phenotype

F

Fig 4.

complete

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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence 
MNISNSQVNR LRHFVRAGLR SLFRPEPQTA VEWADANYYL PKESAYQEGR WETLPFQRAI
MNAMGSDYIR EVNVVKSARV GYSKMLLGVY AYFIEHKQRN TLIWLPTDGD AENFMKTHVE
PTIRDIPSLL ALAPWYGKKH RDNTLTMKRF TNGRGFWCLG GKAAKNYREK SVDVAGYDEL
AAFDDDIEQE GSPTFLGDKR IEGSVWPKSI RGSTPKVRGT CQIERAASES PHFMRFHVAC
PHCGEEQYLK FGDKETPFGL KWTPDDPSSV FYLCEHNACV IRQQELDFTD ARYICEKTGI
WTRDGILWFS SSGEEIEPPD SVTFHIWTAY SPFTTWVQIV KDWMKTKGDT GKRKTFVNTT
LGETWEAKIG ERPDAEVMAE RKEHYSAPVP DRVAYLTAGI DSQLDRYEMR VWGWGPGEES
WLIDRQIIMG RHDDEQTLLR VDEAINKTYT RRNGAEMSIS RICWDTGGID PTIVYERSKK
HGLFRVIPIK GASVYGKPVA SMPRKRNKNG VYLTEIGTDT AKEQIYNRFT LTPEGDEPLP
GAVHFPNNPD IFDLTEAQQL TAEEQVEKWV DGRKKILWDS KKRRNEALDC FVYALAALRI
SISRWQLDLS ALLASLQEED GAATNKKTLA DYARALSGED E
Length

641

Mol. Wt

73.302 kDa

pI

6.5 (calculated)

Extinction coefficient

145,760 - 146,885 (calc based on 24 Y, 20 W, and 9 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=Phage_lambda_A taxon=10710 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)
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Notes

Transcription and Transcriptional Regulation

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

Phage lambda Pr' (late genes)

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<gbrowseImage> name=NC_001416:691..731 source=bacteriophage_lambda type=CDS+DNA preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.


Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

</protect>

Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference
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Expression Studies

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Type Reference Notes
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Expression Resources

See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes
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See Help:Expression_resources for help entering or editing information in this section of EcoliWiki. <protect>

Notes

Accessions Related to Phage lambda A Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments
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Do-It-Yourself Web Tools


Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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See Help:Evolution_families for help entering or editing information in this section of EcoliWiki.

Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ Weigle, J (1966) Assembly of phage lambda in vitro. Proc. Natl. Acad. Sci. U.S.A. 55 1462-6 PubMed
  2. ↑ Sumner-Smith, M et al. (1981) DNA packaging in the lambdoid phages: the role of lambda genes Nu1 and A. Virology 111 642-6 PubMed
  3. ↑ Becker, A et al. (1977) Studies on an in vitro system for the packaging and maturation of phage lambda DNA. Virology 78 277-90 PubMed
  4. ↑ Higgins, RR & Becker, A (1994) Chromosome end formation in phage lambda, catalyzed by terminase, is controlled by two DNA elements of cos, cosN and R3, and by ATP. EMBO J. 13 6152-61 PubMed
  5. ↑ Ortega, ME et al. (2007) The DNA maturation domain of gpA, the DNA packaging motor protein of bacteriophage lambda, contains an ATPase site associated with endonuclease activity. J. Mol. Biol. 373 851-65 PubMed

Categories

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