Phage lambda A:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

A

Synonyms

A, lambdap02

Product description

DNA packaging protein, Component of terminase

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019028

viral capsid

PMID:5227665[1]

IMP: Inferred from Mutant Phenotype

C

Essential for lambda head production

complete

GO:0043493

phage terminase complex

PMID:6264675[2]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0019073

viral DNA genome packaging

PMID:860404[3]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0098036

viral DNA genome packaging, 3' extended cos packaging

PMID:7813452[4]

IDA: Inferred from Direct Assay

P

complete

GO:0016887

ATPase activity

PMID:17870092[5]

IMP: Inferred from Mutant Phenotype

F

Fig 4.

complete

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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence 
MNISNSQVNR LRHFVRAGLR SLFRPEPQTA VEWADANYYL PKESAYQEGR WETLPFQRAI
MNAMGSDYIR EVNVVKSARV GYSKMLLGVY AYFIEHKQRN TLIWLPTDGD AENFMKTHVE
PTIRDIPSLL ALAPWYGKKH RDNTLTMKRF TNGRGFWCLG GKAAKNYREK SVDVAGYDEL
AAFDDDIEQE GSPTFLGDKR IEGSVWPKSI RGSTPKVRGT CQIERAASES PHFMRFHVAC
PHCGEEQYLK FGDKETPFGL KWTPDDPSSV FYLCEHNACV IRQQELDFTD ARYICEKTGI
WTRDGILWFS SSGEEIEPPD SVTFHIWTAY SPFTTWVQIV KDWMKTKGDT GKRKTFVNTT
LGETWEAKIG ERPDAEVMAE RKEHYSAPVP DRVAYLTAGI DSQLDRYEMR VWGWGPGEES
WLIDRQIIMG RHDDEQTLLR VDEAINKTYT RRNGAEMSIS RICWDTGGID PTIVYERSKK
HGLFRVIPIK GASVYGKPVA SMPRKRNKNG VYLTEIGTDT AKEQIYNRFT LTPEGDEPLP
GAVHFPNNPD IFDLTEAQQL TAEEQVEKWV DGRKKILWDS KKRRNEALDC FVYALAALRI
SISRWQLDLS ALLASLQEED GAATNKKTLA DYARALSGED E
Length

641

Mol. Wt

73.302 kDa

pI

6.5 (calculated)

Extinction coefficient

145,760 - 146,885 (calc based on 24 Y, 20 W, and 9 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References
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<motif_map/>

Structure
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Structures

<beststructure> gene=Phage_lambda_A taxon=10710 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ Weigle, J (1966) Assembly of phage lambda in vitro. Proc. Natl. Acad. Sci. U.S.A. 55 1462-6 PubMed
  2. ↑ Sumner-Smith, M et al. (1981) DNA packaging in the lambdoid phages: the role of lambda genes Nu1 and A. Virology 111 642-6 PubMed
  3. ↑ Becker, A et al. (1977) Studies on an in vitro system for the packaging and maturation of phage lambda DNA. Virology 78 277-90 PubMed
  4. ↑ Higgins, RR & Becker, A (1994) Chromosome end formation in phage lambda, catalyzed by terminase, is controlled by two DNA elements of cos, cosN and R3, and by ATP. EMBO J. 13 6152-61 PubMed
  5. ↑ Ortega, ME et al. (2007) The DNA maturation domain of gpA, the DNA packaging motor protein of bacteriophage lambda, contains an ATPase site associated with endonuclease activity. J. Mol. Biol. 373 851-65 PubMed

Categories

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