accC:Gene: Difference between revisions

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*[http://biocyc.org/ECOLI/NEW-IMAGE?type=LOCUS-POSITION&chromosome=COLI-K12&object=EG10276 EcoCyc]
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{{GBrowseLink|ecoli_W3110|AC_000091|3404772|3408121|GBrowse(W3110)}}  
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Revision as of 19:39, 17 August 2011

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Location(s) and DNA Sequence Sequence Features Alleles and Phenotypes Genetic Interactions Genetic Resources Accessions Links References Suggestions

Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

accC

Mnemonic

Acetyl-CoA carboxylase

Synonyms

ECK3243, b3256, JW3224[1]

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Notes

Location(s) and DNA Sequence

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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

BW2952

NC_012759: 3291087..3292436
<gbrowseImage> name=NC_012759:3291087..3292436 source=BW2952 preset=GeneLocation </gbrowseImage>

MG1655

73.37 minutes 

MG1655: 3403939..3405288
<gbrowseImage> name=NC_000913:3403939..3405288 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 3333808..3335157
<gbrowseImage> name=NC_012967:3333808..3335157 source=REL606 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 3405772..3407121
<gbrowseImage> name=AC_000091:3405772..3407121 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 3501684..3503033
<gbrowseImage> name=NC_010473:3501684..3503033 source=DH10B preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

Coding Start (SO:0000323)

MG1655

3403939

Edman degradation

PMID:1370469[2]
PMID:1682920[3]
PMID:9298646[4]


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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

accCE23R

E23R

Loss of homodimerization. No effect on ATP binding

seeded from UniProt:P24182

accCF363A

F363A

Loss of homodimerization. No effect on ATP binding

seeded from UniProt:P24182

accCR366E

R366E

Loss of homodimerization. No effect on ATP binding

seeded from UniProt:P24182

accCR19E

R19E

Loss of homodimerization. No effect on ATP binding

seeded from UniProt:P24182

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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes
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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW3224

Plasmid clone

Shigen

PMID:16769691[5]

Status:Clone OK

Primer 1:GCCCTGGATAAAATTGTTATTGC

Primer 2:CCTTTTTCCTGAAGACCGAGTTT

zhc-6::Tn10

Linked marker

CAG12153 = CGSC7442[6]

est. P1 cotransduction: 18% [7]
Synonyms:zha-6::Tn10

acrF3083::Tn10

Linked marker

CAG12075 = CGSC7447[6]

est. P1 cotransduction: 69% [7]
Synonyms:zhd-3083::Tn10, zhe-3083::Tn10

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10276

EchoBASE (EcoliWiki Page)

EchoBASE:EB0272

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b3256

ECOL199310CYC (EcoliWiki Page)

ECOL199310CYC:C4012

EcoGene (EcoliWiki Page)

EcoGene:EG10276

ECOO157CYC (EcoliWiki Page)

ECOO157CYC:ACCC

CGSC (EcoliWiki Page)

CGSC:29834

ASAP (EcoliWikiPage)

ASAP:ABE-0010677


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Notes

Links

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<protect>

References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ Li, SJ & Cronan, JE Jr (1992) The gene encoding the biotin carboxylase subunit of Escherichia coli acetyl-CoA carboxylase. J. Biol. Chem. 267 855-63 PubMed
  3. ↑ Kondo, H et al. (1991) Acetyl-CoA carboxylase from Escherichia coli: gene organization and nucleotide sequence of the biotin carboxylase subunit. Proc. Natl. Acad. Sci. U.S.A. 88 9730-3 PubMed
  4. ↑ Link, AJ et al. (1997) Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12. Electrophoresis 18 1259-313 PubMed
  5. ↑ Kitagawa, M et al. (2005) Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. DNA Res. 12 291-9 PubMed
  6. ↑ 6.0 6.1 CGSC: The Coli Genetics Stock Center
  7. ↑ 7.0 7.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).

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