accC:Gene: Difference between revisions

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!|Feature Type!!Strain!!Genomic Location!!Evidence!!Reference!!Notes
!|Feature Type!!Strain!!Genomic Location!!Evidence!!Reference!!Notes
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Coding Start (SO:0000323)
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[[MG1655]]
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3403939
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Edman degradation
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PMID:1370469<br />PMID:1682920<br />PMID:9298646<br />
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Revision as of 19:19, 11 May 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Location(s) and DNA Sequence Sequence Features Alleles and Phenotypes Genetic Resources Accessions Links References Suggestions

Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

accC

Mnemonic

Acetyl-CoA carboxylase

Synonyms

ECK3243, b3256, JW3224[1]


Notes

Location(s) and DNA Sequence

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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

BW2952

NC_012759: 3291087..3292436
gbrowse_img.php?coord=3291087..3292436&genome=BW2952&name=NC_012759&trackset=0&width=300&.png

MG1655

73.37 minutes 

MG1655: 3403939..3405288
gbrowse_img.php?coord=3403939..3405288&genome=ecoli&name=MG1655&trackset=0&width=300&.png

REL606

NC_012967: 3333808..3335157
gbrowse_img.php?coord=3333808..3335157&genome=REL606&name=NC_012967&trackset=0&width=300&.png

W3110

 

W3110: 3405772..3407121
gbrowse_img.php?coord=3405772..3407121&genome=ecoli_W3110&name=W3110&trackset=0&width=300&.png

DH10B

DH10B: 3501684..3503033
gbrowse_img.php?coord=3501684..3503033&genome=ecoli_DH10B&name=DH10B&trackset=0&width=300&.png


Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

Coding Start (SO:0000323)

MG1655

3403939

Edman degradation

PMID:1370469[2]
PMID:1682920[3]
PMID:9298646[4]



Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

accCE23R

E23R

Loss of homodimerization. No effect on ATP binding

seeded from UniProt:P24182

accCF363A

F363A

Loss of homodimerization. No effect on ATP binding

seeded from UniProt:P24182

accCR366E

R366E

Loss of homodimerization. No effect on ATP binding

seeded from UniProt:P24182

accCR19E

R19E

Loss of homodimerization. No effect on ATP binding

seeded from UniProt:P24182


Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW3224

Plasmid clone

Shigen

PMID:16769691[5]

Status:Clone OK

Primer 1:GCCCTGGATAAAATTGTTATTGC

Primer 2:CCTTTTTCCTGAAGACCGAGTTT

zhc-6::Tn10

Linked marker

CAG12153 = CGSC7442[6]

est. P1 cotransduction: 18% [7]
Synonyms:zha-6::Tn10

acrF3083::Tn10

Linked marker

CAG12075 = CGSC7447[6]

est. P1 cotransduction: 69% [7]
Synonyms:zhd-3083::Tn10, zhe-3083::Tn10


Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10276

EchoBASE (EcoliWiki Page)

EchoBASE:EB0272

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b3256

ECOL199310CYC (EcoliWiki Page)

ECOL199310CYC:C4012

EcoGene (EcoliWiki Page)

EcoGene:EG10276

ECOO157CYC (EcoliWiki Page)

ECOO157CYC:ACCC

CGSC (EcoliWiki Page)

CGSC:29834

ASAP (EcoliWikiPage)

ASAP:ABE-0010677



Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ Li, SJ & Cronan, JE Jr (1992) The gene encoding the biotin carboxylase subunit of Escherichia coli acetyl-CoA carboxylase. J. Biol. Chem. 267 855-63 PubMed
  3. ↑ Kondo, H et al. (1991) Acetyl-CoA carboxylase from Escherichia coli: gene organization and nucleotide sequence of the biotin carboxylase subunit. Proc. Natl. Acad. Sci. U.S.A. 88 9730-3 PubMed
  4. ↑ Link, AJ et al. (1997) Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12. Electrophoresis 18 1259-313 PubMed
  5. ↑ Kitagawa, M et al. (2005) Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. DNA Res. 12 291-9 PubMed
  6. ↑ 6.0 6.1 CGSC: The Coli Genetics Stock Center
  7. ↑ 7.0 7.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).

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