rseC:On One Page

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

Quickview

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Standard Name

rseC

Gene Synonym(s)

ECK2568, b2570, JW2554[1], JW2554

Product Desc.

protein involved in reduction of the SoxR iron-sulfur cluster[2]; SoxR and Sigma-E factor regulatory protein RseC[3]

Required for the reduction of SoxR[4]

Product Synonyms(s)

RseC protein involved in reduction of the SoxR iron-sulfur cluster[1], B2570[2][1], RseC[2][1] , ECK2568, JW2554, b2570

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): rpoE-rseABC[2], rseABC[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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rseC deletion does not affect sigma E activity. Probable false positive lipoprotein prediction, lipobox not conserved.[4]



Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

rseC

Mnemonic

Regulation of sigma E

Synonyms

ECK2568, b2570, JW2554[1], JW2554

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

58.31 minutes 

MG1655: 2705823..2705344
<gbrowseImage> name=NC_000913:2705344..2705823 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 2629294..2628815
<gbrowseImage> name=NC_012967:2628815..2629294 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 2591149..2591628
<gbrowseImage> name=NC_012759:2591149..2591628 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 2706457..2705978
<gbrowseImage> name=NC_007779:2705978..2706457 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 2797588..2797109
<gbrowseImage> name=NC_010473:2797109..2797588 source=DH10B preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

ΔrseC (Keio:JW2554)

deletion

deletion

PMID:16738554

Shigen
CGSC10030[5]

ΔrseC739::kan

PMID:16738554

CGSC:102812


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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes

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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW2554

Plasmid clone

Shigen

PMID:16769691

Status:Clone OK

Primer 1:GCCATCAAAGAGTGGGCTACCGT

Primer 2:CCtTGGCTCGCGTCTTCCGAAGA

4A12

Kohara Phage

Genobase

PMID:3038334

zfh-208::Tn10

Linked marker

CAG18481 = CGSC7417[5]

est. P1 cotransduction: 16% [6]
Synonyms:zff-208::Tn10

nadB51::Tn10

Linked marker

CAG18480 = CGSC7419[5]

est. P1 cotransduction: 87% [6]

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:G7347

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13178

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003917

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:947052

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2970

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008457

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

RseC

Synonyms

RseC protein involved in reduction of the SoxR iron-sulfur cluster[1], B2570[2][1], RseC[2][1] , ECK2568, JW2554, b2570

Product description

protein involved in reduction of the SoxR iron-sulfur cluster[2]; SoxR and Sigma-E factor regulatory protein RseC[3]

Required for the reduction of SoxR[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 2 predicted transmembrane domains

Daley et al. (2005) [7]

plasma membrane

From EcoCyc[3]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MIKEWATVVS WQNGQALVSC DVKASCSSCA SRAGCGSRVL NKLGPQTTHT IVVPCDEPLV
PGQKVELGIA EGSLLSSALL VYMSPLVGLF LIASLFQLLF ASDVAALCGA ILGGIGGFLI
ARGYSRKFAA RAEWQPIILS VALPPGLVRF ETSSEDASQ
Length

159

Mol. Wt

16.639 kDa

pI

10.5 (calculated)

Extinction coefficient

19,480 - 20,230 (calc based on 2 Y, 3 W, and 6 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

8..142

PF04246 Positive regulator of sigma(E), RseC/MucC

PMID:19920124

<motif_map/>

tmhmm.php?gene=rseC&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=rseC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130495

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947052

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008457

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P46187

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7347

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13178

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947052

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003917

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2970

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Protein

E. coli K-12 MG1655

244

molecules/cell/generation

  • Medium: MOPS Complete
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

119

molecules/cell/generation

  • Medium: MOPS Minimal
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

209

molecules/cell/generation

  • Medium: MOPS Complete without Methionine
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Notes

Transcription and Transcriptional Regulation

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<protect>

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

rpoE-rseABC

rseABC

Figure courtesy of RegulonDB

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Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000913:2705803..2705843 source=MG1655 flip=1 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference


Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b2570 (EcoliWiki Page)

NCBI GEO profiles for rseC

microarray

GenExpDB:b2570 (EcoliWiki Page)

Summary of data for rseC from multiple microarray studies


Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes

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Notes

Accessions Related to rseC Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:G7347

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2970

Escherichia coli str. K-12 substr. MG1655

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b2570

EcoGene

EcoGene:EG13178

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003917

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008457

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments

Shigella flexneri

RSEC

From SHIGELLACYC

E. coli O157

RSEC

From ECOO157CYC


Do-It-Yourself Web Tools

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Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

Pfam (EcoliWiki Page)

PF04246 Positive regulator of sigma(E), RseC/MucC

EcoCyc

EcoCyc:G7347

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13178

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003917

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2970

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008457

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 CGSC: The Coli Genetics Stock Center
  6. 6.0 6.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
  7. Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed

Categories

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