rplD:Gene Product(s)
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Standard name |
RplD |
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Synonyms |
50S ribosomal subunit protein L4[1], B3319[2][1], EryA[2][1], RplD[2][1] , ECK3306, eryA, JW3281, b3319 |
Product description |
50S ribosomal subunit protein L4[2][3]; Component of 50S ribosomal subunit[3]; ribosome[2][3] 50S ribosomal subunit protein L4; erythromycin sensitivity[4] |
EC number (for enzymes) |
|
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
---|---|---|---|---|---|---|---|---|
GO:0003723 |
RNA binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0003735 |
structural constituent of ribosome |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0005840 |
ribosome |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0005840 |
ribosome |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0006350 |
transcription |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0030371 |
translation repressor activity |
IDA: Inferred from Direct Assay |
F |
complete | ||||
GO:0006353 |
transcription termination |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0022625 |
cytosolic large ribosomal subunit |
C |
Missing: evidence, reference | |||||
GO:0006412 |
translation |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0006412 |
translation |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0006417 |
regulation of translation |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0019843 |
rRNA binding |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0019843 |
rRNA binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0030529 |
ribonucleoprotein complex |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0046677 |
response to antibiotic |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Partner Type | Partner | Notes | References | Evidence |
---|---|---|---|---|
Protein |
Subunits of 50S ribosomal subunit |
could be indirect |
||
Protein |
clpA |
Experiment(s):EBI-881374, EBI-891593 | ||
Protein |
deaD |
Experiment(s):EBI-881374, EBI-881486 | ||
Protein |
dnaK |
Experiment(s):EBI-881374, EBI-890853 | ||
Protein |
dps |
Experiment(s):EBI-881374 | ||
Protein |
fusA |
Experiment(s):EBI-881374 | ||
Protein |
gatZ |
Experiment(s):EBI-881374 | ||
Protein |
pflB |
Experiment(s):EBI-881374 | ||
Protein |
rho |
Experiment(s):EBI-881374, EBI-891277 | ||
Protein |
rplA |
Experiment(s):EBI-881374 | ||
Protein |
rplB |
Experiment(s):EBI-881374 | ||
Protein |
rplC |
Experiment(s):EBI-881374 | ||
Protein |
rplE |
Experiment(s):EBI-881374 | ||
Protein |
rplF |
Experiment(s):EBI-881374 | ||
Protein |
rplJ |
Experiment(s):EBI-881374 | ||
Protein |
rplM |
Experiment(s):EBI-881374 | ||
Protein |
rplN |
Experiment(s):EBI-881374 | ||
Protein |
rplQ |
Experiment(s):EBI-881374 | ||
Protein |
rplV |
Experiment(s):EBI-881374 | ||
Protein |
rplX |
Experiment(s):EBI-881374 | ||
Protein |
rpoC |
Experiment(s):EBI-881374, EBI-879261 | ||
Protein |
rpsB |
Experiment(s):EBI-881374 | ||
Protein |
rpsC |
Experiment(s):EBI-881374 | ||
Protein |
rpsD |
Experiment(s):EBI-881374 | ||
Protein |
rpsE |
Experiment(s):EBI-881374 | ||
Protein |
rpsG |
Experiment(s):EBI-881374 | ||
Protein |
rpsJ |
Experiment(s):EBI-881374 | ||
Protein |
rpsK |
Experiment(s):EBI-881374 | ||
Protein |
rpsM |
Experiment(s):EBI-881374 | ||
Protein |
secA |
Experiment(s):EBI-881374, EBI-886105 | ||
Protein |
srmB |
Experiment(s):EBI-881374, EBI-889906, EBI-894853 | ||
Protein |
tufA |
Experiment(s):EBI-881374 | ||
Protein |
rnr |
Experiment(s):EBI-881374, EBI-883997, EBI-891136 | ||
Protein |
ygiF |
Experiment(s):EBI-881374 | ||
Protein |
slyD |
Experiment(s):EBI-1145569 | ||
Protein |
yhjB |
Experiment(s):EBI-1145569 | ||
Protein |
rpsJ |
MALDI(Z-score):17.053160 | ||
Protein |
rplA |
MALDI(Z-score):17.053160 | ||
Protein |
rplM |
MALDI(Z-score):17.053160 | ||
Protein |
rpsM |
MALDI(Z-score):17.053160 | ||
Protein |
rpsC |
MALDI(Z-score):17.053160 | ||
Protein |
rpsD |
MALDI(Z-score):17.053160 | ||
Protein |
rplN |
MALDI(Z-score):17.053160 | ||
Protein |
rplE |
MALDI(Z-score):17.053160 | ||
Protein |
rplB |
MALDI(Z-score):17.053160 | ||
Protein |
rplF |
MALDI(Z-score):17.053160 | ||
Protein |
Subunits of ribosome |
could be indirect |
| |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Compartment | Description | Evidence | Reference/Source | Notes |
---|---|---|---|---|
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Name | |
---|---|
Sequence |
MELVLKDAQS ALTVSETTFG RDFNEALVHQ VVVAYAAGAR QGTRAQKTRA EVTGSGKKPW RQKGTGRARS GSIKSPIWRS GGVTFAARPQ DHSQKVNKKM YRGALKSILS ELVRQDRLIV VEKFSVEAPK TKLLAQKLKD MALEDVLIIT GELDENLFLA ARNLHKVDVR DATGIDPVSL IAFDKVVMTA DAVKQVEEML A |
Length |
201 |
Mol. Wt |
22.086 kDa |
pI |
10.1 (calculated) |
Extinction coefficient |
13,980 (calc based on 2 Y, 2 W, and 0 C residues) |
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Domains/Motifs/Modification Sites
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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Structure
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Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Resource type | Source | Notes/Reference |
---|---|---|
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
Database | Accession | Notes |
---|---|---|
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
Name | URL | Comments |
---|---|---|
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References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Yates, JL & Nomura, M (1980) E. coli ribosomal protein L4 is a feedback regulatory protein. Cell 21 517-22 PubMed
- ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 6.18 6.19 6.20 6.21 6.22 6.23 6.24 6.25 6.26 6.27 6.28 6.29 6.30 6.31 6.32 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 7.0 7.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 8.6 8.7 8.8 8.9 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0003723 ! RNA binding
- GO:0003735 ! structural constituent of ribosome
- GO:0005840 ! ribosome
- GO:0006350 ! transcription
- GO:0030371 ! translation repressor activity
- GO:0006353 ! DNA-templated transcription, termination
- GO:0022625 ! cytosolic large ribosomal subunit
- GO:0006412 ! translation
- GO:0006417 ! regulation of translation
- GO:0019843 ! rRNA binding
- GO:0030529 ! intracellular ribonucleoprotein complex
- GO:0046677 ! response to antibiotic
- Proteins