nuoC:Gene
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Location(s) and DNA Sequence | Sequence Features | Alleles and Phenotypes | Genetic Interactions | Genetic Resources | Accessions | Links | References | Suggestions |
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Nomenclature
See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.
| Standard name |
nuoC |
|---|---|
| Mnemonic |
NADH:ubiquinone oxidoreductase |
| Synonyms |
ECK2280, b2286, JW5375, nuoCD, nuoD[1], nuoD |
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Notes
Location(s) and DNA Sequence
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See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.
| Strain | Map location | Genome coordinates | Genome browsers | Sequence links |
|---|---|---|---|---|
|
MG1655 |
51.73 minutes |
MG1655: 2401879..2400077 |
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NC_012967: 2347448..2345646 |
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NC_012759: 2285882..2287672 |
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W3110 |
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W3110: 2408527..2406725 |
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DH10B: 2493644..2491842 |
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Notes
Sequence Features
See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.
| Feature Type | Strain | Genomic Location | Evidence | Reference | Notes |
|---|---|---|---|---|---|
|
Coding Start (SO:0000323) |
2400080 |
Edman degradation |
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Notes
Alleles and Phenotypes
See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.
| Allele | Nt change(s) | AA change(s) | Phenotype: Type | Phenotype: Description | Reference | Availability | Comments |
|---|---|---|---|---|---|---|---|
|
nuoC(del) (Keio:JW5375) |
deletion |
deletion |
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nuoC768(del)::FRT |
deletion |
Mutagenesis rate |
Decrease in rate of stress induced mutagenesis (SIM) |
Parent Strain: SMR4162 Experimental Strain: SMR12223 |
The mutation conferred a strong decrease in the rate of SIM, the mutation frequency being roughly 90 percent less than the wild type. See table S3 for full experimental results. | ||
|
nuoC768(del)::FRT |
deletion |
Sensitivity to |
Increased SDS-EDTA sensitivity |
Parent Strain: SMR4162 Experimental Strain: SMR12223 |
The mutation conferred an increase in SDS-EDTA sensitivity relative to the wild type. See tables S7 and S1 for a summary of experimental data. | ||
|
SMR4562 nuoC768(del)::FRT yiaG-yfp FRTcatFRT |
Deletion |
Sigma S |
Decrease in SigmaS activity |
Parental Strain: SMR10582 Experimental Strain: SMR12655 |
See table S8 for full experimental results. | ||
|
CAG45114 nuoC768(del)::RTKanFRT |
deltion |
SigmaE activity |
Decrease in sigmaE activity |
Parental Strain: CAG45115 Experimental Strain: SMR15277 |
See table S11 for full experimental data. | ||
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Notes
Genetic Interactions
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| Interactor | Interaction | Allele | Score(s) | Reference(s) | Accessions | Notes |
|---|---|---|---|---|---|---|
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Notes
Genetic Resources
See Help:Gene_resources for help entering information into the Genetic Resources table.
| Resource | Resource Type | Source | Notes/Reference |
|---|---|---|---|
|
JW5375 |
Plasmid clone |
Status:Clone OK Primer 1:GCCGTGAACAATATGACCGACTT Primer 2:CCGCGGTCCACATCTGACATAAC | |
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Kohara Phage |
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Kohara Phage |
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Linked marker |
est. P1 cotransduction: 69% [9] | ||
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zfd-1::Tn10 |
Linked marker |
est. P1 cotransduction: % [9] | |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
| Name | URL | Comments |
|---|---|---|
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References
See Help:References for how to manage references in EcoliWiki.
- ↑ Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ Leif, H et al. (1995) Isolation and characterization of the proton-translocating NADH: ubiquinone oxidoreductase from Escherichia coli. Eur. J. Biochem. 230 538-48 PubMed
- ↑ David, P et al. (2002) Interaction of purified NDH-1 from Escherichia coli with ubiquinone analogues. Biochim. Biophys. Acta 1553 268-78 PubMed
- ↑ Baba, T et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2 2006.0008 PubMed
- ↑ 5.0 5.1 5.2 5.3 Al Mamun, AA et al. (2012) Identity and function of a large gene network underlying mutagenic repair of DNA breaks. Science 338 1344-8 PubMed
- ↑ Kitagawa, M et al. (2005) Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. DNA Res. 12 291-9 PubMed
- ↑ 7.0 7.1 Kohara, Y et al. (1987) The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50 495-508 PubMed
- ↑ 8.0 8.1 CGSC: The Coli Genetics Stock Center
- ↑ 9.0 9.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
