msbA:On One Page

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

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Standard Name

msbA

Gene Synonym(s)

ECK0905, b0914, JW0897[1], JW0897

Product Desc.

ATP-binding transport protein[2][3]

Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase[4]

Product Synonyms(s)

fused lipid transporter subunits of ABC superfamily: membrane component[1], ATP-binding component[1], B0914[2][1], MsbA[2][1], ECK0905, JW0897, b0914

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ycaI[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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MsbA PDB structures 1JSQ, 1PF4 and 1Z2R, and any conclusions derived from these structures, have been retracted due to a software data inversion error (Chang, 2006). A yhjD point mutation (R134C) allows the deletion of the otherwise essential msbA gene (Mamat, 2007). MsbA point mutations confering S18P or S50P suppress the lethal phenotype of a KDO null gutQ kdsD double mutant (Mamat, 2007).[4]



Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

msbA

Mnemonic

Multicopy suppressor of htrB

Synonyms

ECK0905, b0914, JW0897[1], JW0897

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

20.82 minutes 

MG1655: 965844..967592
<gbrowseImage> name=NC_000913:965844..967592 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 983713..985461
<gbrowseImage> name=NC_012967:983713..985461 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 868812..870560
<gbrowseImage> name=NC_012759:868812..870560 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 967043..968791
<gbrowseImage> name=NC_007779:967043..968791 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 1019772..1021520
<gbrowseImage> name=NC_010473:1019772..1021520 source=DH10B preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes
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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

msbAA270T

A270T

Loss of lipid export

seeded from UniProt:P60752

msbAL511P

L511P

Loss of ATPase activity; ATP is still bound

seeded from UniProt:P60752

msbAD512G

D512G

Loss of ATPase activity; ATP is still bound

seeded from UniProt:P60752

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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes
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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW0897

Plasmid clone

Shigen

PMID:16769691

Status:Clone OK

Primer 1:GCCCATAACGACAAAGATCTCTC

Primer 2:CCTTGGCCAAACTGCATTTTGTG

6D12

Kohara Phage

Genobase

PMID:3038334

E1D1

Kohara Phage

Genobase

PMID:3038334

zca-1230::Tn10

Linked marker

CAG18478 = CGSC7356[5]

est. P1 cotransduction: 50% [6]
Synonyms:zbj-1230::Tn10

zcb-3059::Tn10

Linked marker

CAG12094 = CGSC7358[5]

est. P1 cotransduction: 23% [6]

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10613

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10613

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000606

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:945530

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0608

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003113

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MsbA

Synonyms

fused lipid transporter subunits of ABC superfamily: membrane component[1], ATP-binding component[1], B0914[2][1], MsbA[2][1], ECK0905, JW0897, b0914

Product description

ATP-binding transport protein[2][3]

Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0005515

protein binding

PMID:18344567

IDA: Inferred from Direct Assay

F

complete

GO:0034040

lipid-transporting ATPase activity

PMID:18344567

IDA: Inferred from Direct Assay

F

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006869

lipid transport

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01703

P

Seeded from EcoCyc (v14.0)

complete

GO:0006869

lipid transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011917

P

Seeded from EcoCyc (v14.0)

complete

GO:0006869

lipid transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0445

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

PMID:16858726

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0008289

lipid binding

PMID:18344567

IDA: Inferred from Direct Assay

F

complete

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011917

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

GO:0055085

transmembrane transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

P

Seeded from EcoCyc (v14.0)

complete

GO:0055085

transmembrane transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

P

Seeded from EcoCyc (v14.0)

complete

GO:0005319

lipid transporter activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01703

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003439

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011917

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017871

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 6 predicted transmembrane domains

Daley et al. (2005) [7]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD
RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS
TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI
AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ
GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS
LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR
NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA
LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ
Length

582

Mol. Wt

64.462 kDa

pI

8.8 (calculated)

Extinction coefficient

46,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

24..298

PF00664 ABC transporter transmembrane region

PMID:19920124

Domain

383..509

PF00005 ABC transporter

PMID:19920124

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<motif_map/>

tmhmm.php?gene=msbA&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=msbA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128881

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945530

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003113

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P60752

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10613

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10613

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945530

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000606

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0608

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Protein

E. coli K-12 MC4100

2.06E+02

molecules/cell

  • Medium: median data from rich and minimal media
  • Temperature (°C): 37
  • Doubling time (min): Growth Rate(min):
  • Growth phase: other:

emPAI

PMID:18304323

Protein

Ecoli K-12

24.296+/-0.164

Molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): *
  • Growth phase: other: *

Single Molecule Fluorescence

PMID:20671182

mRNA

Ecoli K-12

0.045480549

Molecules/cell

  • Medium:
  • Temperature (°C):
  • Doubling time (min): Growth Rate(min): *
  • Growth phase: other: *

by RNA_Seq

PMID:20671182

Protein

E. coli K-12 MG1655

1044

molecules/cell/generation

  • Medium: MOPS Complete
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

242

molecules/cell/generation

  • Medium: MOPS Minimal
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

Protein

E. coli K-12 MG1655

375

molecules/cell/generation

  • Medium: MOPS Complete without Methionine
  • Temperature (°C): 37
  • Doubling time (min):
  • *Growth phase:
  • OD:
  • other:

Ribosome Profiling

PMID: 24766808

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Notes

Transcription and Transcriptional Regulation

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<protect>

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

ycaI

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Figure courtesy of RegulonDB

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Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000913:965824..965864 source=MG1655 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference
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Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b0914 (EcoliWiki Page)

NCBI GEO profiles for msbA

microarray

GenExpDB:b0914 (EcoliWiki Page)

Summary of data for msbA from multiple microarray studies

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Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes
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Notes

Accessions Related to msbA Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10613

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0608

Escherichia coli str. K-12 substr. MG1655

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b0914

EcoGene

EcoGene:EG10613

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000606

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003113

Escherichia coli str. K-12 substr. MG1655

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Notes

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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments

Anopheles gambiae

  • ENSANGP00000028387 (score: 1.000; bootstrap: 74%)

From Inparanoid:20070104

Apis mellifera

  • ENSAPMP00000011902 (score: 1.000; bootstrap: 73%)
  • ENSAPMP00000035590 (score: 0.076)

From Inparanoid:20070104

Arabidopsis thaliana

  • AT5G39040 (score: 1.000; bootstrap: 90%)
  • AT4G01830 (score: 0.088)
  • AT4G01820 (score: 0.085)
  • AT3G62150 (score: 0.084)
  • AT2G47000 (score: 0.080)
  • AT1G02520 (score: 0.080)
  • AT1G02530 (score: 0.071)
  • AT3G28860 (score: 0.050)

From Inparanoid:20070104

Bos taurus

  • ENSBTAP00000007432 (score: 1.000; bootstrap: 87%)
  • ENSBTAP00000038269 (score: 0.382)
  • ENSBTAP00000003363 (score: 0.221)

From Inparanoid:20070104

Caenorhabditis briggsae

  • WBGene00026762 (score: 1.000; bootstrap: 80%)
  • WBGene00028069 (score: 0.337)
  • WBGene00034271 (score: 0.334)
  • WBGene00037006 (score: 0.277)
  • WBGene00037005 (score: 0.269)
  • WBGene00023573 (score: 0.248)
  • WBGene00023577 (score: 0.243)
  • WBGene00023572 (score: 0.231)
  • WBGene00023575 (score: 0.231)
  • WBGene00037162 (score: 0.217)
  • WBGene00037161 (score: 0.212)
  • WBGene00033821 (score: 0.211)
  • WBGene00037165 (score: 0.175)
  • WBGene00032204 (score: 0.141)
  • WBGene00034135 (score: 0.137)

From Inparanoid:20070104

Caenorhabditis elegans

  • WBGene00003996 (score: 1.000; bootstrap: 81%)
  • WBGene00004003 (score: 0.330)
  • WBGene00003995 (score: 0.321)
  • WBGene00003997 (score: 0.279)
  • WBGene00003998 (score: 0.265)
  • WBGene00004008 (score: 0.245)
  • WBGene00004006 (score: 0.238)
  • WBGene00004007 (score: 0.222)
  • WBGene00004001 (score: 0.221)
  • WBGene00003999 (score: 0.220)
  • WBGene00004002 (score: 0.214)
  • WBGene00004009 (score: 0.212)
  • WBGene00004000 (score: 0.211)
  • WBGene00004005 (score: 0.148)
  • WBGene00004004 (score: 0.139)

From Inparanoid:20070104

Canis familiaris

  • ENSCAFP00000002684 (score: 1.000; bootstrap: 74%)
  • ENSCAFP00000002677 (score: 0.681)
  • ENSCAFP00000003871 (score: 0.488)
  • ENSCAFP00000017653 (score: 0.428)

From Inparanoid:20070104

Ciona intestinalis

  • ENSCINP00000009257 (score: 1.000; bootstrap: 89%)
  • ENSCINP00000009176 (score: 0.717)
  • ENSCINP00000018552 (score: 0.484)
  • ENSCINP00000018541 (score: 0.460)
  • ENSCINP00000014551 (score: 0.333)
  • ENSCINP00000015244 (score: 0.329)

From Inparanoid:20070104

Danio rerio

  • ZDB-GENE-050410-6 (score: 1.000; bootstrap: 99%)
  • ZDB-CDNA-050410-6 (score: 1.000; bootstrap: 99%)
  • ZDB-GENE-030616-225 (score: 0.059)
  • ZDB-GENE-030616-245 (score: 0.052)

From Inparanoid:20070104

Dictyostelium discoideum

  • DDB0201666 (score: 1.000; bootstrap: 85%)
  • DDB0208540 (score: 0.099)
  • DDB0229852 (score: 0.064)

From Inparanoid:20070104

Drosophila melanogaster

  • FBgn0010241 (score: 1.000; bootstrap: 59%)
  • FBgn0004512 (score: 0.307)
  • FBgn0004513 (score: 0.285)
  • FBgn0035695 (score: 0.255)

From Inparanoid:20070104

Drosophila pseudoobscura

  • GA21135-PA (score: 1.000; bootstrap: 57%)
  • GA17746-PA (score: 0.300)
  • GA10136-PA (score: 0.288)

From Inparanoid:20070104

Gallus gallus

  • ENSGALP00000014477 (score: 1.000; bootstrap: 98%)
  • ENSGALP00000017711 (score: 0.512)
  • ENSGALP00000017690 (score: 0.419)

From Inparanoid:20070104

Homo sapiens

  • ENSP00000265724 (score: 1.000; bootstrap: 87%)
  • ENSP00000265723 (score: 0.729)
  • ENSP00000263817 (score: 0.447)
  • ENSP00000258738 (score: 0.287)

From Inparanoid:20070104

Macaca mulatta

  • ENSMMUP00000018185 (score: 1.000; bootstrap: 75%)
  • ENSMMUP00000014135 (score: 0.361)
  • ENSMMUP00000008900 (score: 0.344)
  • ENSMMUP00000010273 (score: 0.211)

From Inparanoid:20070104

Monodelphis domestica

  • ENSMODP00000012733 (score: 1.000; bootstrap: 93%)
  • ENSMODP00000012812 (score: 0.798)
  • ENSMODP00000012716 (score: 0.697)
  • ENSMODP00000009711 (score: 0.431)

From Inparanoid:20070104

Mus musculus

  • MGI:97568 (score: 1.000; bootstrap: 85%)
  • MGI:97570 (score: 1.000; bootstrap: 86%)
  • MGI:97569 (score: 0.700)
  • MGI:1351619 (score: 0.417)

From Inparanoid:20070104

Oryza gramene

  • Q7FMW2 (score: 1.000; bootstrap: 76%)
  • Q5JLI1 (score: 0.706)
  • Q8GU71 (score: 0.704)
  • Q7FMW3 (score: 0.619)
  • Q5JLI4 (score: 0.605)
  • Q8RVT7 (score: 0.599)
  • Q8GU72 (score: 0.595)
  • Q8GU73 (score: 0.571)
  • Q6Z6U9 (score: 0.555)
  • Q9LGX1 (score: 0.541)
  • Q8GU69 (score: 0.534)
  • Q5N9P2 (score: 0.523)
  • Q8GU76 (score: 0.341)
  • Q8GU77 (score: 0.340)
  • Q8GU75 (score: 0.333)
  • Q7XUZ8 (score: 0.331)
  • Q6UC91 (score: 0.318)
  • Q7EZL2 (score: 0.314)
  • Q6YUU5 (score: 0.308)
  • Q8GU78 (score: 0.307)
  • Q6UNK5 (score: 0.298)
  • O23998 (score: 0.270)
  • Q8GU81 (score: 0.265)
  • Q7XUP9 (score: 0.265)
  • Q8GU74 (score: 0.264)
  • Q8GU68 (score: 0.258)
  • Q8GU67 (score: 0.250)
  • Q7EYH1 (score: 0.246)
  • Q8H7L0 (score: 0.236)
  • Q8GU79 (score: 0.235)
  • Q8GU80 (score: 0.223)
  • Q7EZL3 (score: 0.183)
  • Q9FSQ6 (score: 0.151)
  • Q7EZL1 (score: 0.114)
  • Q5KQM4 (score: 0.095)
  • Q6Z894 (score: 0.077)
  • Q5JN97 (score: 0.057)

From Inparanoid:20070104

Pan troglodytes

  • ENSPTRP00000033133 (score: 1.000; bootstrap: 89%)
  • ENSPTRP00000045311 (score: 0.731)
  • ENSPTRP00000021540 (score: 0.274)
  • ENSPTRP00000032398 (score: 0.110)

From Inparanoid:20070104

Rattus norvegicus

  • ENSRNOP00000011166 (score: 1.000; bootstrap: 87%)
  • ENSRNOP00000038721 (score: 0.840)
  • ENSRNOP00000042556 (score: 0.705)
  • ENSRNOP00000045152 (score: 0.281)

From Inparanoid:20070104

Saccharomyces cerevisiae

  • YPL270W (score: 1.000; bootstrap: 74%)
  • YLR188W (score: 0.217)

From Inparanoid:20070104

Schizosaccharomyces pombe

  • SPCC6633 (score: 1.000; bootstrap: 72%)

From Inparanoid:20070104

Takifugu rubripes

  • NEWSINFRUP00000161094 (score: 1.000; bootstrap: 81%)
  • NEWSINFRUP00000161095 (score: 0.700)
  • NEWSINFRUP00000172828 (score: 0.412)
  • NEWSINFRUP00000182094 (score: 0.386)

From Inparanoid:20070104

Tetraodon nigroviridis

  • GSTENP00024825001 (score: 1.000; bootstrap: 80%)
  • GSTENP00034001001 (score: 0.370)
  • GSTENP00034000001 (score: 0.333)
  • GSTENP00034623001 (score: 0.254)
  • GSTENP00033999001 (score: 0.066)

From Inparanoid:20070104

Xenopus tropicalis

  • ENSXETP00000049177 (score: 1.000; bootstrap: 86%)

From Inparanoid:20070104

Shigella flexneri

MSBA

From SHIGELLACYC

E. coli O157

MSBA

From ECOO157CYC

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Do-It-Yourself Web Tools

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Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

Pfam (EcoliWiki Page)

PF00664 ABC transporter transmembrane region

Pfam (EcoliWiki Page)

PF00005 ABC transporter

Panther (EcoliWiki Page)

PTHR24221:SF91

Superfamily (EcoliWiki Page)

SUPERFAMILY:52540

Superfamily (EcoliWiki Page)

SUPERFAMILY:90123

EcoCyc

EcoCyc:EG10613

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10613

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000606

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0608

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003113

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 CGSC: The Coli Genetics Stock Center
  6. ↑ 6.0 6.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
  7. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed

Categories

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