mdtQ:On One Page

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

Quickview

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Standard Name

mdtQ

Gene Synonym(s)

yohG, ECK2131, b2138, JW5838[1][2], JW5838, yohH, b2139

Product Desc.

predicted outer membrane protein[2]; putative channel/filament protein[3]

Product Synonyms(s)

predicted outer membrane protein[1], B2138[2][1], MdtQ[2][1], YohG[2][1] , ECK2131, JW5838, yohG, yohH, b2139

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yohG[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

mdtQ

Mnemonic
Synonyms

yohG, ECK2131, b2138, JW5838[1][2], JW5838, yohH, b2139

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

47.96 minutes 

MG1655: 2226433..2225345
<gbrowseImage> name=NC_000913:2225345..2226433 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 2178561..2179925
<gbrowseImage> name=NC_012967:2178561..2179925 source=REL606 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 2231745..2230657
<gbrowseImage> name=NC_007779:2230657..2231745 source=W3110 preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

ΔyohG::kan

deletion

Biolog:respiration

unable to respire Acetate

PMID:16095938


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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes

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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

Plasmid clone

Shigen

PMID:16769691

Status:

Primer 1:

Primer 2:

1E1

Kohara Phage

Genobase

PMID:3038334

2B2

Kohara Phage

Genobase

PMID:3038334

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG12020

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12020

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001937

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:949123

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB4379

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0007067

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YohG

Synonyms

predicted outer membrane protein[1], B2138[2][1], MdtQ[2][1], YohG[2][1] , ECK2131, JW5838, yohG, yohH, b2139

Product description

predicted outer membrane protein[2]; putative channel/filament protein[3]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0005215

transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003423

F

Seeded from EcoCyc (v14.0)

complete

GO:0005215

transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010131

F

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003423

P

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010131

P

Seeded from EcoCyc (v14.0)

complete

GO:0008289

lipid binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010131

F

Seeded from EcoCyc (v14.0)

complete

GO:0009279

cell outer membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0998

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010131

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0031225

anchored to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9901

C

Seeded from EcoCyc (v14.0)

complete

GO:0046677

response to antibiotic

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0046

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MQVAEQRIQL AEAQAKAVAT QDGPQIDFSA DMERQKMSAE GLMGPFALND PAAGTTGPWY
TNGTFGLTAG WHLDIWGKNR AEVTARLGTV KARAAEREQT RQLLAGSVAR LYWEWQTQAA
LNTVLQQIEK EQNTIIATDR QLYQNGITSS VEGVETDINA SKTRQQLNDV AGKMKIIEAR
LSALTNNQTK SLKLKPVALP KVASQLPDEL GYSLLARRAD LQAAHWYVES SLSTIDAAKA
AFYPDINLMA FLQQDALHLS DLFRHSAQQM GVTAGLTLPI FDSGRLNANL DIAKAESNLS
IASYNKAVVE AVNDVARAAS QVQTLAEKNQ HQAQIERDAL RVVGLAQARF NAGIIAGSRV
SEARIPALRE RANGLLLQGQ WLDASIQLTG ALGGGYKR
Length

398

Mol. Wt

43.258 kDa

pI

8.5 (calculated)

Extinction coefficient

50,420 (calc based on 8 Y, 7 W, and 0 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-21

UniProt Manual:Signal Peptides

UniProt:P33369


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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mdtQ taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

ASAP

ASAP:ABE-0007067

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:949123

Escherichia coli str. K-12 substr. MG1655

ASAP (EcoliWiki Page)

ASAP:ABE-0007071

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P33369

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12020

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12020

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:949123

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001937

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB4379

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Notes

Transcription and Transcriptional Regulation

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

yohG

Figure courtesy of RegulonDB

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Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000913:2226413..2226453 source=MG1655 flip=1 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference


Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b2138 (EcoliWiki Page)

NCBI GEO profiles for mdtQ

microarray

GenExpDB:b2138 (EcoliWiki Page)

Summary of data for mdtQ from multiple microarray studies


Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes

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Notes

Accessions Related to mdtQ Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG12020

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB4379

Escherichia coli str. K-12 substr. MG1655

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b2138

EcoGene

EcoGene:EG12020

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001937

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0007067

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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Evolution

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Homologs in Other Organisms

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<protect> See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments

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Do-It-Yourself Web Tools

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Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

PFAM (EcoliWiki Page)

PFAM:PF02321

EcoCyc

EcoCyc:EG12020

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12020

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001937

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB4379

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0007067

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7

Categories

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