marR:Gene

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Nomenclature Location(s) and DNA Sequence Sequence Features Alleles and Phenotypes Genetic Interactions Genetic Resources Accessions Links References Suggestions

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

marR

Mnemonic

Multiple antibiotic resistance

Synonyms

ECK1523, b1530, JW5248, cfxB, soxQ, inaR[1], inaR

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

34.85 minutes 

MG1655: 1617144..1617578
<gbrowseImage> name=NC_000913:1617144..1617578 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 1586886..1587320
<gbrowseImage> name=NC_012967:1586886..1587320 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 1509203..1509637
<gbrowseImage> name=NC_012759:1509203..1509637 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 1620834..1621268
<gbrowseImage> name=NC_007779:1620834..1621268 source=W3110 preset=GeneLocation </gbrowseImage>

DH10B

DH10B: 1706769..1707203
<gbrowseImage> name=NC_010473:1706769..1707203 source=DH10B preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

ΔmarR (Keio:JW5248)

deletion

deletion

PMID:16738554[2]

Shigen
CGSC11268[3]

marR::Tn5KAN-2 (FB20348)

Insertion at nt 200 in Plus orientation

PMID:15262929[4]

E. coli Genome Project:FB20348

does not contain pKD46

marR::Tn5KAN-2 (FB20349)

Insertion at nt 200 in Plus orientation

PMID:15262929[4]

E. coli Genome Project:FB20349

contains pKD46

marRV45E

V45E

Increased transcription of the region II transcript

seeded from UniProt:P27245

marRR77L

R77L

Increased transcription of the region II transcript

seeded from UniProt:P27245

marR

Deletion

marR11

PMID:10602715[5]

CGSC:70116

ΔmarR751::kan

PMID:16738554[2]

CGSC:101766


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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes

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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

JW5248

Plasmid clone

Shigen

PMID:16769691[6]

Status:Clone OK

Primer 1:GCCAAAAGTACCAGCGATCTGTT

Primer 2:CCtGGCAGGACTTTCTTAAGCAA

2H2

Kohara Phage

Genobase

PMID:3038334[7]

2B2

Kohara Phage

Genobase

PMID:3038334[7]

zdd-235::Tn10

Linked marker

CAG18461 = CGSC7378[3]

est. P1 cotransduction: % [8]
Synonyms:zdc-235::Tn10

zdi-925::Tn10

Linked marker

CAG12151 = CGSC7385[3]

est. P1 cotransduction: % [8]
Synonyms:zdh-925::Tn10

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG11435

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11435

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001399

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:945825

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1405

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0005110

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 Baba, T et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2 2006.0008 PubMed
  3. 3.0 3.1 3.2 CGSC: The Coli Genetics Stock Center
  4. 4.0 4.1 Kang, Y et al. (2004) Systematic mutagenesis of the Escherichia coli genome. J. Bacteriol. 186 4921-30 PubMed
  5. Oethinger, M et al. (2000) Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump. Antimicrob. Agents Chemother. 44 10-3 PubMed
  6. Kitagawa, M et al. (2005) Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. DNA Res. 12 291-9 PubMed
  7. 7.0 7.1 Kohara, Y et al. (1987) The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50 495-508 PubMed
  8. 8.0 8.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).

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