ftsA:Expression
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Overview
This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.
Cellular Levels
Molecule | Organism or Strain | Value | Units | Experimental Conditions | Assay used | Notes | Reference(s) |
---|---|---|---|---|---|---|---|
Protein |
E. coli D1210 |
175 |
molecules/cell |
|
quantitative western |
||
Protein |
E. coli D1210 |
200 |
molecules/cell |
|
quantitative western |
||
Protein |
E. coli D1210 |
127 |
molecules/cell |
|
quantitative western |
||
Protein |
E. coli D1210 |
100 |
molecules/cell |
|
quantitative western |
||
Protein |
E. coli D1210 |
74 |
molecules/cell |
|
quantitative western |
||
Protein |
E. coli D1210 |
48 |
molecules/cell |
|
quantitative western |
||
Protein |
E. coli D1210 |
45 |
molecules/cell |
|
quantitative western |
||
Protein |
E. coli D1210 |
43 |
molecules/cell |
|
quantitative western |
||
Protein |
Ecoli K-12 |
58.922+/-0.223 |
Molecules/cell |
|
Single Molecule Fluorescence |
||
mRNA |
Ecoli K-12 |
0.161648177 |
Molecules/cell |
|
by RNA_Seq |
||
Protein |
E. coli K-12 MG1655 |
984 |
molecules/cell/generation |
|
Ribosome Profiling |
||
Protein |
E. coli K-12 MG1655 |
575 |
molecules/cell/generation |
|
Ribosome Profiling |
||
Protein |
E. coli K-12 MG1655 |
1013 |
molecules/cell/generation |
|
Ribosome Profiling |
||
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Notes
Transcription and Transcriptional Regulation
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Notes
This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.
Overproduction of FtsA causes long non-septate filaments to form and inhibits normal cell septation. [4]
Overproduction does block division but transcription from cloned fts promoters is not further repressed. [5]
RcsB effects the efficiency of the transcription of ftsA1p. Specifically, causing it too increase in efficiency as more of RcsB is added. [6]
Translation and Regulation of Translation
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This picture shows the sequence around the N-terminus.
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Notes
This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.
Turnover and Regulation of Turnover
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Notes
This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.
Experimental
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Mutations Affecting Expression
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Allele Name | Mutation | Phenotype | Reference |
---|---|---|---|
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Expression Studies
See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.
Type | Reference | Notes |
---|---|---|
microarray |
NCBI GEO profiles for ftsA | |
microarray |
Summary of data for ftsA from multiple microarray studies | |
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Expression Resources
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Resource Name | Resource Type | Description | Source | Notes |
---|---|---|---|---|
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Notes
Accessions Related to ftsA Expression
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Database | Accession | Notes |
---|---|---|
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
Name | URL | Comments |
---|---|---|
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References
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- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Wang, H & Gayda, RC (1992) Quantitative determination of FtsA at different growth rates in Escherichia coli using monoclonal antibodies. Mol. Microbiol. 6 2517-24 PubMed
- ↑ 2.0 2.1 Taniguchi, Y et al. (2010) Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells. Science 329 533-8 PubMed
- ↑ 3.0 3.1 3.2 Li, GW et al. (2014) Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. Cell 157 624-35 PubMed
- ↑ Wang, HC & Gayda, RC (1990) High-level expression of the FtsA protein inhibits cell septation in Escherichia coli K-12. J. Bacteriol. 172 4736-40 PubMed
- ↑ Dewar, SJ et al. (1989) Transcriptional regulation of cell division genes in Escherichia coli. Mol. Microbiol. 3 1371-7 PubMed
- ↑ Carballès, F et al. (1999) Regulation of Escherichia coli cell division genes ftsA and ftsZ by the two-component system rcsC-rcsB. Mol. Microbiol. 34 442-50 PubMed
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