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Gene |

Product(s) |

Expression|

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Standard Name	ftnB
Gene Synonym(s)	yecI, ECK1900, b1902, JW1890^[1]^[2], JW1890
Product Desc.	predicted ferritin-like protein^[2]^[3] Ferritin-like protein, function unknown^[4]
Product Synonyms(s)	predicted ferritin-like protein^[1], B1902^[2]^[1], YecI^[2]^[1], FtnB^[2]^[1] , ECK1900, JW1890, yecI, b1902
Function from GO	<GO_nr />
Knock-Out Phenotype
Regulation/Expression	transcription unit(s): ftnB^[2], yecI
Regulation/Activity
Quick Links
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</protect> See Help:Quickview for help with entering information in the Quickview table. <protect></protect>

Notes

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Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name	ftnB
Mnemonic	Ferritin
Synonyms	yecI, ECK1900, b1902, JW1890^[1]^[2], JW1890
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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain	Map location	Genome coordinates	Genome browsers	Sequence links
MG1655	42.78 minutes	MG1655: 1984949..1985452 <gbrowseImage> name=NC_000913:1984949..1985452 source=MG1655 preset=GeneLocation </gbrowseImage>	EcoCyc GBrowse(MG1655)	FASTA Dump EcoCyc Sequence Dump
BW2952		NC_012759: 1877432..1877935 <gbrowseImage> name=NC_012759:1877432..1877935 source=BW2952 preset=GeneLocation </gbrowseImage>	GBrowse (BW2952)	FASTA Dump
W3110		W3110: 1989062..1989565 <gbrowseImage> name=NC_007779:1989062..1989565 source=W3110 preset=GeneLocation </gbrowseImage>	GBrowse(W3110)	FASTA Dump
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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type	Strain	Genomic Location	Evidence	Reference	Notes
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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele	Nt change(s)	Reference	Availability	Comments
yecI::Tn5KAN-I-SceI (FB20512)	Insertion at nt 299 in Plus orientation	PMID:15262929	E. coli Genome Project:FB20512	contains pKD46
ΔftnB752::kan		PMID:16738554	CGSC:106190
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Notes

Genetic Interactions

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Interactor	Interaction	Allele	Score(s)	Reference(s)	Accessions	Notes
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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource	Resource Type	Source	Notes/Reference
	Plasmid clone	Shigen	PMID:16769691 Status: Primer 1: Primer 2:
7F11	Kohara Phage	Genobase	PMID:3038334
18A9	Kohara Phage	Genobase	PMID:3038334
16B12	Kohara Phage	Genobase	PMID:3038334
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc	EcoCyc:G7033	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG13175	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120003619	Escherichia coli str. K-12 substr. MG1655
NCBI (EcoliWiki Page)	GeneID:946407	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB2967	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0006333	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name	YecI
Synonyms	predicted ferritin-like protein^[1], B1902^[2]^[1], YecI^[2]^[1], FtnB^[2]^[1] , ECK1900, JW1890, yecI, b1902
Product description	predicted ferritin-like protein^[2]^[3] Ferritin-like protein, function unknown^[4]
EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005737	cytoplasm	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0963	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005737	cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0086	C	Seeded from EcoCyc (v14.0)	complete
	GO:0006826	iron ion transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001519	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006879	cellular iron ion homeostasis	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001519	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006879	cellular iron ion homeostasis	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008331	P	Seeded from EcoCyc (v14.0)	complete
	GO:0008199	ferric iron binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001519	F	Seeded from EcoCyc (v14.0)	complete
	GO:0008199	ferric iron binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008331	F	Seeded from EcoCyc (v14.0)	complete
	GO:0016491	oxidoreductase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009078	F	Seeded from EcoCyc (v14.0)	complete
	GO:0046914	transition metal ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009078	F	Seeded from EcoCyc (v14.0)	complete
	GO:0055114	oxidation reduction	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009078	P	Seeded from EcoCyc (v14.0)	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	References	Evidence
Protein	phnN	PMID:16606699	Experiment(s):EBI-1141256
Protein	napC	PMID:16606699	Experiment(s):EBI-1141256
Protein	nadE	PMID:16606699	Experiment(s):EBI-1141256
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MATAGMLLKL NSQMNREFYA SNLYLHLSNW CSEQSLNGTA TFLRAQAQSN VTQMMRMFNF MKSVGATPIV KAIDVPGEKL NSLEELFQKT MEEYEQRSST LAQLADEAKE LNDDSTVNFL RDLEKEQQHD GLLLQTILDE VRSAKLAGMC PVQTDQHVLN VVSHQLH
Length	167
Mol. Wt	18.894 kDa
pI	5.1 (calculated)
Extinction coefficient	9,970 - 10,220 (calc based on 3 Y, 1 W, and 2 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes	References
Domain	7..144	PF00210 Ferritin-like domain		PMID:19920124
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=ftnB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:16129852	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:946407	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0006333	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P0A9A2	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:G7033	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG13175	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:946407	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120003619	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB2967	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Cellular Levels

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See Help:Cellular levels

Molecule	Organism or Strain	Value	Units	Experimental Conditions	Assay used	Reference(s)
Protein	E. coli K-12 MG1655	333	molecules/cell/generation	Medium: MOPS Complete Temperature (°C): 37 Doubling time (min): *Growth phase: OD: other:	Ribosome Profiling	PMID: 24766808
Protein	E. coli K-12 MG1655	170	molecules/cell/generation	Medium: MOPS Minimal Temperature (°C): 37 Doubling time (min): *Growth phase: OD: other:	Ribosome Profiling	PMID: 24766808
Protein	E. coli K-12 MG1655	239	molecules/cell/generation	Medium: MOPS Complete without Methionine Temperature (°C): 37 Doubling time (min): *Growth phase: OD: other:	Ribosome Profiling	PMID: 24766808
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Notes

Transcription and Transcriptional Regulation

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)
ftnB
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Figure courtesy of RegulonDB

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Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000913:1984929..1984969 source=MG1655 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name	Mutation	Phenotype	Reference
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Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type	Reference	Notes
microarray	GEO Profiles:b1902 (EcoliWiki Page)	NCBI GEO profiles for ftnB
microarray	GenExpDB:b1902 (EcoliWiki Page)	Summary of data for ftnB from multiple microarray studies
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Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name	Resource Type	Description	Source	Notes
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Notes

Accessions Related to ftnB Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc	EcoCyc:G7033	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB2967	Escherichia coli str. K-12 substr. MG1655
EcoliGenExpDB (EcoliWiki Page)	EcoliGenExpDB:b1902
EcoGene	EcoGene:EG13175	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120003619	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0006333	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism	Homologs (Statistics)	Comments
Apis mellifera	ENSAPMP00000019996 (score: 1.000; bootstrap: 100%)	From Inparanoid:20070104
Arabidopsis thaliana	AT2G40300 (score: 1.000; bootstrap: 100%) AT3G56090 (score: 0.733) AT3G11050 (score: 0.602) AT5G01600 (score: 0.573)	From Inparanoid:20070104
Caenorhabditis briggsae	WBGene00024156 (score: 1.000; bootstrap: 100%) WBGene00033041 (score: 0.769)	From Inparanoid:20070104
Monodelphis domestica	ENSMODP00000002273 (score: 1.000; bootstrap: 100%) ENSMODP00000026412 (score: 0.452) ENSMODP00000005165 (score: 0.388) ENSMODP00000009409 (score: 0.388) ENSMODP00000002263 (score: 0.369) ENSMODP00000017165 (score: 0.252) ENSMODP00000007163 (score: 0.246) ENSMODP00000025098 (score: 0.166) ENSMODP00000023431 (score: 0.163)	From Inparanoid:20070104
Oryza gramene	P29390 (score: 1.000; bootstrap: 100%) P29036 (score: 0.852) Q5G1L6 (score: 0.744) Q8LK80 (score: 0.733) Q6DQK1 (score: 0.733) Q8L5K0 (score: 0.733) Q94KA2 (score: 0.721) Q6VVA5 (score: 0.441) Q945F6 (score: 0.441) Q4FCZ8 (score: 0.429)	From Inparanoid:20070104
Shigella flexneri	YECI	From SHIGELLACYC
E. coli O157	YECI	From ECOO157CYC
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Do-It-Yourself Web Tools

Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
Pfam (EcoliWiki Page)	PF00210 Ferritin-like domain
Superfamily (EcoliWiki Page)	SUPERFAMILY:47240
PFAM (EcoliWiki Page)	PFAM:PF00210
EcoCyc	EcoCyc:G7033	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG13175	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120003619	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB2967	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0006333	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^4.0 ^4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.

ftnB:On One Page

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Notes

Gene

Nomenclature

Notes

Location(s) and DNA Sequence

Notes

Sequence Features

Notes

Alleles and Phenotypes

Notes

Genetic Interactions

Notes

Genetic Resources

Notes

Accessions in Other Databases

Notes

Links

Product(s)

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

Expression

Overview

Cellular Levels

Notes

Transcription and Transcriptional Regulation

Notes

Translation and Regulation of Translation

Notes

Turnover and Regulation of Turnover

Notes

Experimental

Notes

Accessions Related to ftnB Expression

Notes

Links

Evolution

Homologs in Other Organisms

Do-It-Yourself Web Tools

Notes

Families

Notes

Links

References

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