Phage f1 I:On One Page

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Standard Name	I
Gene Synonym(s)	XI
Product Desc.	I: assembly protein , inner membrane protein
Product Synonyms(s)	protein I , Gene I protein , G1P protein XI, G11P , I*
Function from GO	<GO_nr />
Knock-Out Phenotype
Regulation/Expression
Regulation/Activity
Quick Links
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Notes

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References

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Gene

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Nomenclature

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<protect> See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name	I
Mnemonic
Synonyms	XI
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Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain	Map location	Genome coordinates	Genome browsers	Sequence links
		J02448: 3196..4242 <gbrowseImage> name=J02448:1104..6334 source=bacteriophage_f1 preset=GeneLocation </gbrowseImage>	GBrowse (Phage_f1)	FASTA Dump
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Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type	Strain	Genomic Location	Evidence	Reference	Notes
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Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele	Nt change(s)	AA change(s)	Phenotype: Type	Phenotype: Description	Reference	Availability	Comments
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Genetic Interactions

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Interactor	Interaction	Allele	Score(s)	Reference(s)	Accessions	Notes
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Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource	Resource Type	Source	Notes/Reference
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Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
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Links

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Name	URL	Comments
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Product(s)

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Gene

Gene Product(s)

Expression

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name	I, XI
Synonyms	protein I , Gene I protein , G1P protein XI, G11P , I*
Product description	I: assembly protein , inner membrane protein
EC number (for enzymes)
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Function

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Gene Ontology <protect> See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0042963	phage assembly	PMID:7752229	IMP: Inferred from Mutant Phenotype		P		complete
	GO:0016021	integral to membrane	PMID:2457024	IDA: Inferred from Direct Assay		C		complete
	GO:0005887	integral to plasma membrane	PMID:1556066	IDA: Inferred from Direct Assay		C	I and XI	complete
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Interactions

See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
Protein	thioredoxin, trxA Uniprot P0AA25	Cytoplasmic domain of G1P, interacts at adhesion zone	PMID:3881414 PMID:2746731	IMP; see PMID:3881414 Table 3. Mutants with no host trxA failed to grow. PMID:2746731 discusses interaction of thioredoxin and G1P.
DNA	Packing signal (PS) on phage DNA	Recognises PS to encapsidate phage DNA	PMID:2746731	IMP; Gene mutations promoted assembly of ss plasmid DNAs that lacked a PS into filamentous transducing particles, suggesting that the wild-type proteins may normally interact with the PS.
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Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
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Structure and Physical Properties

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Physical Properties <protect> See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	MAVYFVTGKL GSGKTLVSVG KIQDKIVAGC KIATNLDLRL QNLPQVGRFA KTPRVLRIPD KPSISDLLAI GRGNDSYDEN KNGLLVLDEC GTWFNTRSWN DKERQPIIDW FLHARKLGWD IIFLVQDLSI VDKQARSALA ENVVYCRRLD RITLPFVGTL YSLITGSKMP LPKLHVGVVK YGDSQLSPTV ERWLYTGKNL YNAYDTKQAF SSNYDSGVYS YLTPYLSHGR YFKPLNLGQK MKLTKIYLKK FSRVLCLAIG FASAFTYSYI TQPKPEVKKV VSQTYDFDKF TIDSSQRLNL SYRYVFKDSK GKLINSDDLQ KQGYSLTYID LCTVSIKKGN SNEIVKCN
Length	348
Mol. Wt	39.529 kDa
pI	9.9 (calculated)
Extinction coefficient	58,790 - 59,540 (calc based on 21 Y, 5 W, and 6 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki. Type Residues Description Notes References Domain 241-295 (internal signal sequence) responsible for inhibition of cell growth causes loss of membrane potential required for insertion in membrane PMID:2457024 edit table

<motif_map/>

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki. Structures <beststructure> gene=Phage_f1_I taxon=10863 </beststructure> Models View models at: Protein Model Portal PSI-PRED Genomes TO Protein (GTOP) edit table

</protect> Structure figures Notes See PMID: 10547282 for info on charges of residues in alpha helix and importance to functioning of pI but not to pXI. Gene Product Resources [back to top] See Help:Product_resources for help with entering or editing information in this section of EcoliWiki. Resource type Source Notes/Reference edit table Notes Accessions in Other Databases [back to top] See Help:Gene_accessions for help with entering information into the Gene Accessions table. Database Accession Notes edit table Notes Links [back to top] Name URL Comments edit table References [back to top] See Help:References for how to manage references in EcoliWiki. Categories [back to top] Expression [back to top] {{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css> Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page     Overview Transcription Translation Turnover Experimental Links References Suggestions Overview Intracellular Levels [back to top] See Help:Cellular levels Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s) edit table Notes Transcription and Transcriptional Regulation [back to top] <protect> See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki. Transcription unit(s) edit table |} </protect> Notes Translation and Regulation of Translation [back to top] <gbrowseImage> name=J02448:3176..3216 source=bacteriophage_f1 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus. </protect> Notes Turnover and Regulation of Turnover </protect> Notes Experimental [back to top] Mutations Affecting Expression <protect> See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki. Allele Name Mutation Phenotype Reference edit table Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki. Type Reference Notes edit table Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki. Resource Name Resource Type Description Source Notes edit table Notes Accessions Related to Phage_f1_I Expression [back to top] See Help:Gene_accessions for help with entering information into the Gene Accessions table. Database Accession Notes edit table Notes Links [back to top] Name URL Comments edit table References [back to top] See Help:References for how to manage references in EcoliWiki. Categories [back to top] Evolution [back to top] {{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css> Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page     Homologs Families Links References Suggestions Homologs in Other Organisms [back to top] See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki. Organism Homologs (Statistics) Comments edit table Do-It-Yourself Web Tools BLAST CDD InParanoid YOGY Notes Families [back to top] See Help:Evolution_families for help entering or editing information in this section of EcoliWiki. Database Accession Notes edit table Notes Links [back to top] Name URL Comments edit table References [back to top] See Help:References for how to manage references in EcoliWiki. Categories [back to top]