Phage f1 I:Gene Product(s)

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Gene

Gene Product(s)

Expression

Evolution

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Nomenclature

Function

Interactions

Localization

Sequence

Domains

Structure

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Accessions

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References

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Nomenclature

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Standard name	I, XI
Synonyms	protein I , Gene I protein , G1P protein XI, G11P , I*
Product description	I: assembly protein , inner membrane protein
EC number (for enzymes)
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Function

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Gene Ontology <protect> See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0042963	phage assembly	PMID:7752229	IMP: Inferred from Mutant Phenotype		P		complete
	GO:0016021	integral to membrane	PMID:2457024	IDA: Inferred from Direct Assay		C		complete
	GO:0005887	integral to plasma membrane	PMID:1556066	IDA: Inferred from Direct Assay		C	I and XI	complete
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Interactions

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Partner Type	Partner	Notes	References	Evidence
Protein	thioredoxin, trxA Uniprot P0AA25	Cytoplasmic domain of G1P, interacts at adhesion zone	PMID:3881414 PMID:2746731	IMP; see PMID:3881414 Table 3. Mutants with no host trxA failed to grow. PMID:2746731 discusses interaction of thioredoxin and G1P.
DNA	Packing signal (PS) on phage DNA	Recognises PS to encapsidate phage DNA	PMID:2746731	IMP; Gene mutations promoted assembly of ss plasmid DNAs that lacked a PS into filamentous transducing particles, suggesting that the wild-type proteins may normally interact with the PS.
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Localization

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Compartment	Description	Evidence	Reference/Source	Notes
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Structure and Physical Properties

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Physical Properties <protect> See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	MAVYFVTGKL GSGKTLVSVG KIQDKIVAGC KIATNLDLRL QNLPQVGRFA KTPRVLRIPD KPSISDLLAI GRGNDSYDEN KNGLLVLDEC GTWFNTRSWN DKERQPIIDW FLHARKLGWD IIFLVQDLSI VDKQARSALA ENVVYCRRLD RITLPFVGTL YSLITGSKMP LPKLHVGVVK YGDSQLSPTV ERWLYTGKNL YNAYDTKQAF SSNYDSGVYS YLTPYLSHGR YFKPLNLGQK MKLTKIYLKK FSRVLCLAIG FASAFTYSYI TQPKPEVKKV VSQTYDFDKF TIDSSQRLNL SYRYVFKDSK GKLINSDDLQ KQGYSLTYID LCTVSIKKGN SNEIVKCN
Length	348
Mol. Wt	39.529 kDa
pI	9.9 (calculated)
Extinction coefficient	58,790 - 59,540 (calc based on 21 Y, 5 W, and 6 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki. Type Residues Description Notes References Domain 241-295 (internal signal sequence) responsible for inhibition of cell growth causes loss of membrane potential required for insertion in membrane PMID:2457024 edit table

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Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki. Structures <beststructure> gene=Phage_f1_I taxon=10863 </beststructure> Models View models at: Protein Model Portal PSI-PRED Genomes TO Protein (GTOP) edit table

</protect> Structure figures Notes See PMID: 10547282 for info on charges of residues in alpha helix and importance to functioning of pI but not to pXI. Gene Product Resources [back to top] See Help:Product_resources for help with entering or editing information in this section of EcoliWiki. Resource type Source Notes/Reference edit table Notes Accessions in Other Databases [back to top] See Help:Gene_accessions for help with entering information into the Gene Accessions table. Database Accession Notes edit table Notes Links [back to top] Name URL Comments edit table References [back to top] See Help:References for how to manage references in EcoliWiki. Categories [back to top]