rpsL:Gene Product(s): Difference between revisions

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Revision as of 19:37, 8 October 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

RpsL

Synonyms

30S ribosomal subunit protein S12[1], B3342[2][1], StrA[2][1], AsuB[2][1], RpsL[2][1]

Product description

30S ribosomal subunit protein S12[2][3];

Component of 30S ribosomal subunit[2][3]; ribosome[2][3]

30S ribosomal subunit protein S12; RNA chaperone[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0046677

response to antibiotic

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0046

P

Seeded from EcoCyc [5]

complete

GO:0030529

ribonucleoprotein complex

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0687

C

Seeded from EcoCyc [5]

complete

GO:0019843

rRNA binding

GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

SP_KW:KW-0699
HAMAP:MF_00403

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0015935

small ribosomal subunit

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005679

C

Seeded from EcoCyc [5]

complete

GO:0006412

translation

GO_REF:0000002
GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR005679
InterPro:IPR006032
HAMAP:MF_00403

P

Seeded from EcoCyc 12.5 [6]

complete

GO:0005840

ribosome

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006032

C

Seeded from EcoCyc 12.5 [6]

complete

GO:0003735

structural constituent of ribosome

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005679
InterPro:IPR006032

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0003723

RNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0694

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0000049

tRNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0820

F

Seeded from EcoCyc [5]

complete

GO:0022626

cytosolic ribosome

C

Seeded from EcoCyc 11.1[3].

required field missing

GO:0000372

Group I intron splicing

PMID:7958841[7]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc [5]

complete

GO:0033120

positive regulation of RNA splicing

PMID:7958841[7]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc [5]

complete

GO:0034336

misfolded RNA binding

PMID:7958841[7]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc [5]

complete

GO:0034337

RNA folding

PMID:7958841[7]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc [5]

complete

GO:0006412

translation

PMID:4579428[8]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 11.1[3]. Data in Table IV.

complete

GO:0003735

structural constituent of ribosome

PMID:4587209[9]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 11.1[3].

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0022627

cytosolic small ribosomal subunit

PMID:4587209[9]

IDA: Inferred from Direct Assay

C

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of 30S ribosomal subunit

could be indirect

Protein

ycgL

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

hns

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

yedI

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

rplO

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

rplA

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

rpsI

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

rpsD

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

cspI

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

rplB

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

yedN

PMID:16606699[10]

Experiment(s):EBI-1145610

Protein

Subunits of ribosome

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes

cytoplasm

From EcoCyc[3]


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MATVNQLVRK PRARKVAKSN VPALEACPQK RGVCTRVYTT TPKKPNSALR KVCRVRLTNG
FEVTSYIGGE GHNLQEHSVI LIRGGRVKDL PGVRYHTVRG ALDCSGVKDR KQARSKYGVK RPKA
Length

124

Mol. Wt

13.736 kDa

pI

11.3 (calculated)

Extinction coefficient

5,960 - 6,460 (calc based on 4 Y, W, and 4 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes

Initiator Methionine

1

Removed

UniProt:P0A7S3

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=rpsL taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10911-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0A7S3

PFAM (EcoliWiki Page)

PFAM:PF00164

RefSeq (EcoliWiki Page)

RefSeq:NP_417801


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 6.2 6.3 6.4 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.0 7.1 7.2 7.3 Coetzee, T et al. (1994) Escherichia coli proteins, including ribosomal protein S12, facilitate in vitro splicing of phage T4 introns by acting as RNA chaperones. Genes Dev 8 1575-88 PubMed
  8. ↑ Held, WA et al. (1973) Reconstitution of Escherichia coli 30 S ribosomal subunits from purified molecular components. J. Biol. Chem. 248 5720-30 PubMed
  9. ↑ 9.0 9.1 Wittmann-Liebold, B (1973) Studies on the primary structure of 20 proteins from Escherichia coli ribosomes by means of an improved protein sequenator. FEBS Lett. 36 247-9 PubMed
  10. ↑ 10.00 10.01 10.02 10.03 10.04 10.05 10.06 10.07 10.08 10.09 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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