coaE:Gene Product(s): Difference between revisions

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<span id="Structure"></span><big>'''Structure'''</big>
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<span id='Structure'></span><big>'''Structure'''</big><br />
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==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===


Revision as of 15:31, 23 July 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

CoaE

Synonyms

dephospho-CoA kinase[1], B0103[2][1], YacE[2][1], CoaE[2][1]

Product description

EG12312[2][3]

Dephospho-CoA kinase; final step in CoA synthesis[4]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0015937

coenzyme A biosynthetic process

GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

SP_KW:KW-0173
HAMAP:MF_00376

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0004140

dephospho-CoA kinase activity

GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

EC:2.7.1.24
HAMAP:MF_00376

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005524

ATP binding

GO_REF:0000002
GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR001977
SP_KW:KW-0067
HAMAP:MF_00376

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc [6]

complete

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded from EcoCyc [6]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc [6]

complete

GO:0004140

dephospho-CoA kinase activity

PMID:11292795[7]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0015937

coenzyme A biosynthetic process

PMID:11292795[7]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0030288

outer membrane-bounded periplasmic space

C

Seeded from Riley et al 2006 [1].

required fields missing

GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc

complete

GO:0004140

dephospho-CoA kinase activity

GO_REF:0000020
GO_REF:0000003
PMID:11292795[7]

IDA: Inferred from Direct Assay

HAMAP:MF_00376
EC:2.7.1.24

F

Seeded from EcoCyc

complete

GO:0005524

ATP binding

GO_REF:0000020
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

HAMAP:MF_00376
InterPro:IPR001977
SP_KW:KW-0067

F

Seeded from EcoCyc

complete

GO:0005737

cytoplasm

GO_REF:0000020
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

HAMAP:MF_00376
SP_KW:KW-0963
SP_SL:SL-0086

C

Seeded from EcoCyc

complete

GO:0015937

coenzyme A biosynthetic process

GO_REF:0000020
GO_REF:0000004
PMID:11292795[7]

IDA: Inferred from Direct Assay

HAMAP:MF_00376
SP_KW:KW-0173

P

Seeded from EcoCyc

complete

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded from EcoCyc

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MRYIVALTGG IGSGKSTVAN AFADLGINVI DADIIARQVV EPGAPALHAI ADHFGANMIA
ADGTLQRRAL RERIFANPEE KNWLNALLHP LIQQETQHQI QQATSPYVLW VVPLLVENSL
YKKANRVLVV DVSPETQLKR TMQRDDVTRE HVEQILAAQA TREARLAVAD DVIDNNGAPD
AIASDVARLH AHYLQLASQF VSQEKP
Length

206

Mol. Wt

22.621 kDa

pI

6.2 (calculated)

Extinction coefficient

16,960 (calc based on 4 Y, 2 W, and C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes

Domain

4 - 200

DPCK

UniProt:P0A6I9

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure>coaE 562</beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG12312-MONOMER

PDB (EcoliWiki Page)

PDB:1N3B

UniProt (EcoliWiki Page)

UniProt:P0A6I9

PFAM (EcoliWiki Page)

PFAM:PF01121

RefSeq (EcoliWiki Page)

RefSeq:NP_414645

ModBase (EcoliWiki Page)

ModBase:P0A6I9


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. ↑ 6.0 6.1 6.2 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  7. ↑ 7.0 7.1 7.2 7.3 Mishra, P et al. (2001) Identification of yacE (coaE) as the structural gene for dephosphocoenzyme A kinase in Escherichia coli K-12. J. Bacteriol. 183 2774-8 PubMed

Categories

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