galE:Gene Product(s): Difference between revisions

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<noinclude>{{TabsTop}}
<noinclude>{{TabsTop}}
{{Tab|Quickview|galE}}{{Tab|Gene|galE}}{{Tab On|Gene Product(s)|galE}}{{Tab|Expression|galE}}{{Tab|Evolution|galE}}{{Tab|On One Page|galE}}{{TabsBottom}}
{{Tab|Quickview|galE}}{{Tab|Gene|galE}}{{Tab On|Gene Product(s)|galE}}{{Tab|Expression|galE}}{{Tab|Evolution|galE}}{{Tab|On One Page|galE}}{{TabsBottom}}
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|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
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</noinclude>
</noinclude>[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006012_!_galactose metabolic process]][[Category:GO:0009242_!_colanic acid biosynthetic process]][[Category:GO:0016052_!_carbohydrate catabolic process]][[Category:GO:0009435_!_NAD biosynthetic process]][[Category:GO:0009269_!_response to desiccation]][[Category:GO:0042280_!_cell surface antigen activity, host-interacting]][[Category:GO:0030113_!_capsule (sensu Bacteria)]]
==Nomenclature==
==Nomenclature==
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{|{{Prettytable}}
{|{{Prettytable}}
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!{{table heading style}} |Synonyms
!{{table heading style}} |Synonyms
|
|
UDP-galactose-4-epimerase<ref name='LIB:Riley_2006'/>, B0759<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GalD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GalE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
UDP-galactose-4-epimerase product<ref name='LIB:Riley_2006'/>, B0759 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GalD product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GalE product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
|-
|-
!{{table heading style}} |Product description
!{{table heading style}} |Product description
|
|
UDP-glucose 4-epimerase monomer<ref name='LIB:EcoCyc10.6'/>; UDP-glucose 4-epimerase monomer<ref name='LIB:EcoCyc11.1'/>; Component of [[:Category:Complex:UDP-glucose 4-epimerase|UDP-glucose 4-epimerase]]<ref name='LIB:EcoCyc10.6'/>; UDP-glucose 4-epimerase<ref name='LIB:EcoCyc10.6'/>; UDP-glucose 4-epimerase<ref name='LIB:EcoCyc11.1'/>
UDP-glucose 4-epimerase monomer<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
 
Component of ; [[:Category:Complex:UDP-glucose 4-epimerase|UDP-glucose 4-epimerase]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


|-
|-
!{{table heading style}} |EC number (for enzymes)
!{{table heading style}} |EC number (for enzymes)
|
|
*[http://www.brenda.uni-koeln.de/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2]<ref name='LIB:Riley_2006'/>
** [http://www.brenda.uni-koeln.de/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2]<ref name='LIB:Riley_2006'/>
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==Function==
==Function==
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===Gene Ontology===
<big>'''Gene Ontology'''</big>
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!Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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{{Product_GO_help}}
===Interactions===
 
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<span id="Interactions"></span><big>'''Interactions'''</big>
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!Partner Type!!Partner!!Notes
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could be indirect   
could be indirect   
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===Notes===
===Notes===


==Localization==
==Localization==
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!Compartment!!Description!!Evidence!!Notes
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===Notes===
===Notes===


==Structure and Physical Properties==
==Structure and Physical Properties==
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===Physical Properties===
<span id="Sequence"></span><big>'''Physical Properties'''</big>
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48360 - 48735 (calc based on 14 Y, 5 W, and 3 C residues)  
48360 - 48735 (calc based on 14 Y, 5 W, and 3 C residues)  
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===Domains/Motifs/Modification Sites===
 
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<big>'''Domains/Motifs/Modification Sites'''</big>
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!Type!!Residues!!Description!!Notes
!Type!!Residues!!Description!!Notes
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===Structure===
 
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<span id="Structure"></span><big>'''Structure'''</big>
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!Structure Type!!Organism!!Accession!!Residues covered!!Notes
!Structure Type!!Organism!!Accession!!Residues covered!!Notes
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==Gene Product Resources==
==Gene Product Resources==
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===Notes===
===Notes===


==Accessions in Other Databases==
==Accessions in Other Databases==
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==Links==
==Links==
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==References==
==References==
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<references/>
<references/>
__NOTOC__
__NOTOC__
[[Category:GO:0005737]][[Category:GO:0006012]][[Category:GO:0009242]][[Category:GO:0016052]][[Category:GO:0009435]][[Category:GO:0009269]][[Category:GO:0042280]][[Category:GO:0030113]][[Category:Complex:UDP-glucose 4-epimerase]]</noinclude>
</noinclude>

Revision as of 08:39, 28 July 2007

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

GalE product

Synonyms

UDP-galactose-4-epimerase product[1], B0759 product[2][1], GalD product[2][1], GalE product[2][1]

Product description

UDP-glucose 4-epimerase monomer[2][3];

Component of ; UDP-glucose 4-epimerase[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0006012

galactose metabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009242

colanic acid biosynthetic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0016052

carbohydrate catabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009435

NAD biosynthetic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009269

response to desiccation

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0042280

cell surface antigen activity, host-interacting

F

Seeded from Riley et al 2006 [1].

required fields missing

GO:0030113

capsule (sensu Bacteria)

C

Seeded from EcoCyc 11.1[3].

required fields missing

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See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Interactions

Partner Type Partner Notes

Protein

Subunits of UDP-glucose 4-epimerase

could be indirect

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Notes

Localization

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MRVLVTGGSG YIGSHTCVQL LQNGHDVIIL DNLCNSKRSV LPVIERLGGK HPTFVEGDIR
NEALMTEILH DHAIDTVIHF AGLKAVGESV QKPLEYYDNN VNGTLRLISA MRAANVKNFI
FSSSATVYGD QPKIPYVESF PTGTPQSPYG KSKLMVEQIL TDLQKAQPDW SIALLRYFNP
VGAHPSGDMG EDPQGIPNNL MPYIAQVAVG RRDSLAIFGN DYPTEDGTGV RDYIHVMDLA
DGHVVAMEKL ANKPGVHIYN LGAGVGNSVL DVVNAFSKAC GKPVNYHFAP RREGDLPAYW
ADASKADREL NWRVTRTLDE MAQDTWHWQS RHPQGYPD
Mol. Wt

37.27 kDa (calc) [2]

pI

6.28[2]

Extinction coefficient

48360 - 48735 (calc based on 14 Y, 5 W, and 3 C residues)

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See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Domains/Motifs/Modification Sites

Type Residues Description Notes
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Structure

Structure Type Organism Accession Residues covered Notes

X-RAY DIFFRACTION

Escherichia coli

2UDP UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL

X-RAY DIFFRACTION

Escherichia coli

1XEL UDP-GALACTOSE 4-EPIMERASE FROM ESCHERICHIA COLI

X-RAY DIFFRACTION

Escherichia coli

1UDC STRUCTURE OF UDP-GALACTOSE-4-EPIMERASE COMPLEXED WITH UDP-MANNOSE

X-RAY DIFFRACTION

Escherichia coli

1UDB STRUCTURE OF UDP-GALACTOSE-4-EPIMERASE COMPLEXED WITH UDP-4-DEOXY-4-FLUORO-ALPHA-D-GLUCOSE

X-RAY DIFFRACTION

Escherichia coli

1UDA STRUCTURE OF UDP-GALACTOSE-4-EPIMERASE COMPLEXED WITH UDP-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE

X-RAY DIFFRACTION

Escherichia coli

1NAI UDP-GALACTOSE 4-EPIMERASE FROM ESCHERICHIA COLI, OXIDIZED

X-RAY DIFFRACTION

Escherichia coli

1NAH UDP-GALACTOSE 4-EPIMERASE FROM ESCHERICHIA COLI, REDUCED

X-RAY DIFFRACTION

Escherichia coli

1LRL Crystal Structure of UDP-Galactose 4-Epimerase Mutant Y299C Complexed with UDP-Glucose

X-RAY DIFFRACTION

Escherichia coli

1LRK Crystal Structure of Escherichia coli UDP-Galactose 4-Epimerase Mutant Y299C Complexed with UDP-N-acetylglucosamine

X-RAY DIFFRACTION

Escherichia coli

1LRJ Crystal Structure of E. coli UDP-Galactose 4-Epimerase Complexed with UDP-N-Acetylglucosamine

X-RAY DIFFRACTION

Escherichia coli

1KVU UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL

X-RAY DIFFRACTION

Escherichia coli

1KVT UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL

X-RAY DIFFRACTION

Escherichia coli

1KVS UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL

X-RAY DIFFRACTION

Escherichia coli

1KVR UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL

X-RAY DIFFRACTION

Escherichia coli

1KVQ UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL

X-RAY DIFFRACTION

Escherichia coli

1A9Z UDP-GALACTOSE 4-EPIMERASE MUTANT S124A/Y149F COMPLEXED WITH UDP-GALACTOSE

X-RAY DIFFRACTION

Escherichia coli

1A9Y UDP-GALACTOSE 4-EPIMERASE MUTANT S124A/Y149F COMPLEXED WITH UDP-GLUCOSE

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Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:UDPGLUCEPIM-MONOMER

UniProt (EcoliWiki Page)

UniProt:P09147

PFAM (EcoliWiki Page)

PFAM:PF01370

RefSeq (EcoliWiki Page)

RefSeq:NP_415280

ModBase (EcoliWiki Page)

ModBase:P09147

PDB (EcoliWiki Page)

PDB:1A9Y

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Notes

Links

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Name URL Comments
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References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7