galE:Gene Product(s): Difference between revisions
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GO:0003978 | |||
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UDP-glucose 4-epimerase activity | |||
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GOA:interpro<br />GO_REF:0000002 | |||
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IEA: Inferred from Electronic Annotation | |||
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InterPro:IPR005886 | |||
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F | |||
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Seeded from [[EcoCyc]] (v14.0) | |||
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GO:0003978 | |||
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UDP-glucose 4-epimerase activity | |||
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GOA:spec<br />GO_REF:0000003 | |||
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IEA: Inferred from Electronic Annotation | |||
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EC:5.1.3.2 | |||
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F | |||
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Seeded from [[EcoCyc]] (v14.0) | |||
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GO:0005829 | |||
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cytosol | |||
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PMID:16858726 | |||
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IDA: Inferred from Direct Assay | |||
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C | |||
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Seeded from [[EcoCyc]] (v14.0) | |||
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GO:0006012 | |||
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galactose metabolic process | |||
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PMID:13914787 | |||
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IMP: Inferred from Mutant Phenotype | |||
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P | |||
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Seeded from [[EcoCyc]] (v14.0) | |||
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Revision as of 16:37, 11 June 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
GalE |
|---|---|
| Synonyms |
UDP-galactose-4-epimerase[1], B0759[2][1], GalD[2][1], GalE[2][1] |
| Product description |
UDP-glucose 4-epimerase[2][3]; Component of UDP-glucose 4-epimerase[2][3] UDP-galactose 4-epimerase; hexose-1-phosphate uridylyltransferase[4] |
| EC number (for enzymes) | |
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0006012 |
galactose metabolic process |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| GO:0005975 |
carbohydrate metabolic process |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| GO:0016052 |
carbohydrate catabolic process |
IGI: Inferred from Genetic Interaction |
P |
complete | ||||
| GO:0016857 |
racemase and epimerase activity, acting on carbohydrates and derivatives |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0006012 |
galactose metabolic process |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
complete | ||||
| GO:0003978 |
UDP-glucose 4-epimerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
|||
| GO:0003978 |
UDP-glucose 4-epimerase activity |
GOA:spec |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
|||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc (v14.0) |
||||
| GO:0006012 |
galactose metabolic process |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc (v14.0) |
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| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of UDP-glucose 4-epimerase |
could be indirect |
||
|
Protein |
rsuA |
Experiment(s):EBI-1137880 | ||
|
Protein |
yfcH |
Experiment(s):EBI-1137880 | ||
|
Protein |
nadE |
Experiment(s):EBI-1137880 | ||
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Source | Notes |
|---|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MRVLVTGGSG YIGSHTCVQL LQNGHDVIIL DNLCNSKRSV LPVIERLGGK HPTFVEGDIR NEALMTEILH DHAIDTVIHF AGLKAVGESV QKPLEYYDNN VNGTLRLISA MRAANVKNFI FSSSATVYGD QPKIPYVESF PTGTPQSPYG KSKLMVEQIL TDLQKAQPDW SIALLRYFNP VGAHPSGDMG EDPQGIPNNL MPYIAQVAVG RRDSLAIFGN DYPTEDGTGV RDYIHVMDLA DGHVVAMEKL ANKPGVHIYN LGAGVGNSVL DVVNAFSKAC GKPVNYHFAP RREGDLPAYW ADASKADREL NWRVTRTLDE MAQDTWHWQS RHPQGYPD |
|---|---|
| Length |
338 |
| Mol. Wt |
37.264 kDa |
| pI |
6.3 (calculated) |
| Extinction coefficient |
48,360 - 48,735 (calc based on 14 Y, 5 W, and 3 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
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Structure
|
Structure figures
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
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| ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 Fietta, A et al. (1981) R-factor-mediated suppression of the galactose-sensitive phenotype of Escherichia coli K-12 galE Mutants. Plasmid 6 78-85 PubMed
- ↑ 6.0 6.1 6.2 Vorgias, CE et al. () Overexpression and purification of the galactose operon enzymes from Escherichia coli. Protein Expr. Purif. 2 330-8 PubMed
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
- ↑ SOFFER, RL (1961) Enzymatic expression of genetic units of function concerned with galactose metabolism in Escherichia coli. J. Bacteriol. 82 471-8 PubMed
- ↑ 9.0 9.1 9.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
Categories
- GO:0006012 ! galactose metabolic process
- GO:0005975 ! carbohydrate metabolic process
- GO:0016052 ! carbohydrate catabolic process
- GO:0016857 ! racemase and epimerase activity, acting on carbohydrates and derivatives
- GO:0005737 ! cytoplasm
- GO:0003978 ! UDP-glucose 4-epimerase activity
- GO:0005829 ! cytosol
- Proteins
- GO:0009242 ! colanic acid biosynthetic process
- GO:0009435 ! NAD biosynthetic process
- GO:0009269 ! response to desiccation
- GO:0042280 ! cell surface antigen activity, host-interacting
- GO:0030113 ! capsule (sensu Bacteria)
- Complex:UDP-glucose 4-epimerase
- Products with structures in PDB
- RefGenome Annotated Gene