lacZ:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''lacZ''  
''lacZ''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK0341, b0344, JW0335''<ref name='LIB:Riley_2006'/>
''ECK0341, b0344, JW0335''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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β-galactosidase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
β-galactosidase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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beta-D-Galactosidase<ref name='LIB:EcoGene'/>
beta-D-Galactosidase<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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beta-D-galactosidase<ref name='LIB:Riley_2006'/>, B0344<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, LacZ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, β-D-galactosidase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, lactase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, β-D-galactoside galactohydrolase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
beta-D-galactosidase<ref name='LIB:Riley_2006'/>, B0344<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, LacZ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, β-D-galactosidase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, lactase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, β-D-galactoside galactohydrolase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])
'''Biological Process'''
* GO:0005990 lactose catabolic process ([http://www.geneontology.org/GO.evidence.shtml IMP])
 
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!align=left {{table_heading_style}} |Knock-Out Phenotype
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unable to grow on lactose as a carbon source
unable to grow on lactose as a carbon source
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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:lacZYA|lacZYA]]<ref name='LIB:EcoCyc10.6'/>, lacZ, OP00045, lacAYZ  
transcription unit(s): [[:Category:Txn_unit:lacZYA|lacZYA]]<ref name='LIB:EcoCyc10.6'/>, lacZ, OP00045, lacAYZ  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=lacZ&loc=MG1655:365529..362455,W3110:365529..362455,REL606:338861..335787 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=338861&end=335787&gene=lacZ&aa=mtmitdslavvlqrrdwenpgvtqlnrlaahppfaswrnseeartdrpsqqlrslngewrfawfpapeavpeswlecdlpeadtvvvpsnwqmhgydapiytnvtypitvnppfvptenptgcysltfnvdeswlqegqtriifdgvnsafhlwcngrwvgygqdsrlpsefdlsaflragenrlavmvlrwsdgsyledqdmwrmsgifrdvsllhkpttqisdfhvatrfnddfsravleaevqmcgelrdylrvtvslwqgetqvasgtapfggeiiderggyadrvtlrlnvenpklwsaeipnlyravvelhtadgtlieaeacdvgfrevriengllllngkpllirgvnrhehhplhgqvmdeqtmvqdillmkqnnfnavrcshypnhplwytlcdryglyvvdeaniethgmvpmnrltddprwlpamservtrmvqrdrnhpsviiwslgnesghganhdalyrwiksvdpsrpvqyegggadttatdiicpmyarvdedqpfpavpkwsikkwlslpgetrplilceyahamgnslggfakywqafrqyprlqggfvwdwvdqslikydengnpwsayggdfgdtpndrqfcmnglvfadrtphpalteakhqqqffqfrlsgqtievtseylfrhsdnellhwmvaldgkplasgevpldvapqgkqlielpelpqpesagqlwltvrvvqpnatawseaghisawqqwrlaenlsvtlpaashaiphlttsemdfcielgnkrwqfnrqsgflsqmwigdkkqlltplrdqftrapldndigvseatridpnawverwkaaghyqaeaallqctadtladavlittahawqhqgktlfisrktyridgsgqmaitvdvevasdtphpariglncqlaqvaervnwlglgpqenypdrltaacfdrwdlplsdmytpyvfpsenglrcgtrelnygphqwrgdfqfnisrysqqqlmetshrhllhaeegtwlnidgfhmgiggddswspsvsaefqlsagryhyqlvwcqk Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=lacZ+AND+escherichia+coli Pubmed(lacZ)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=lacZ Textpresso(lacZ)]


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Revision as of 23:47, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

lacZ

Gene Synonym(s)

ECK0341, b0344, JW0335[1]

Product Desc.

β-galactosidase[2][3];

Component of β-galactosidase[2][3]

beta-D-Galactosidase[4]

Product Synonyms(s)

beta-D-galactosidase[1], B0344[2][1], LacZ[2][1], β-D-galactosidase[2][1], lactase[2][1], β-D-galactoside galactohydrolase[2][1]

Function from GO

Molecular Function

Biological Process

Knock-Out Phenotype

unable to grow on lactose as a carbon source

Regulation/Expression

transcription unit(s): lacZYA[2], lacZ, OP00045, lacAYZ

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(lacZ)    Textpresso(lacZ)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Repressed during biofilm formation. LacZ has an Ig-like beta-sandwich domain (residues 221-334 align to PFAM: PF00703). ebgA, uidA and lacZ are paralogs. Binds TrxA (Kumar, 2004)[5].[4]



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Kumar, JK et al. (2004) Proteomic analysis of thioredoxin-targeted proteins in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 101 3759-64 PubMed
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