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References Suggestions


Standard Name


Gene Synonym(s)

ECK0341, b0344, JW0335[1], JW0335

Product Desc.


Component of β-galactosidase[2][3]


Product Synonyms(s)

beta-D-galactosidase[1], B0344[2][1], LacZ[2][1], beta-D-galactosidase[2][1], lactase[2][1], beta-D-galactoside galactohydrolase[2][1] , ECK0341, JW0335, b0344

Function from GO

<GO_nr />

Knock-Out Phenotype

unable to grow on lactose as a carbon source


transcription unit(s): lacZYA[2], lacZ, OP00045, lacAYZ

Quick Links

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Repressed during biofilm formation. LacZ has an Ig-like beta-sandwich domain (residues 221-334 align to PFAM: PF00703). ebgA, uidA and lacZ are paralogs. Binds TrxA (Kumar, 2004)[5].[4]


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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Kumar, JK et al. (2004) Proteomic analysis of thioredoxin-targeted proteins in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 101 3759-64 PubMed