parC:Gene Product(s): Difference between revisions
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!{{table heading style}} |Standard name | !align=left {{table heading style}} |Standard name | ||
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ParC product | ParC product | ||
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!{{table heading style}} |Synonyms | !align=left {{table heading style}} |Synonyms | ||
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DNA topoisomerase IV, subunit A product<ref name='LIB:Riley_2006'/>, B3019 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ParC product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | DNA topoisomerase IV, subunit A product<ref name='LIB:Riley_2006'/>, B3019 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ParC product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!{{table heading style}} |Product description | !align=left {{table heading style}} |Product description | ||
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topoisomerase IV subunit A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | topoisomerase IV subunit A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | ||
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!{{table heading style}} |EC number (for enzymes) | !align=left {{table heading style}} |EC number (for enzymes) | ||
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* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.- 5.99.1.-]<ref name='LIB:Riley_2006'/> | * [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.- 5.99.1.-]<ref name='LIB:Riley_2006'/> | ||
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status | !|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status | ||
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!Partner Type!!Partner!!Notes | !|Partner Type!!Partner!!Notes | ||
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Protein | Protein | ||
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could be indirect | could be indirect | ||
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Protein | Protein | ||
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could be indirect | could be indirect | ||
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!Compartment!!Description!!Evidence!!Notes | !|Compartment!!Description!!Evidence!!Notes | ||
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cytoplasm | cytoplasm | ||
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From EcoCyc<ref name='LIB:EcoCyc11.1'/> | From EcoCyc<ref name='LIB:EcoCyc11.1'/> | ||
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!{{table heading style}} |Sequence | !align=left {{table heading style}} |Sequence | ||
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[http://biocyc.org/ECOLI/sequence-aa?object=EG10686-MONOMER at EcoCyc] | [http://biocyc.org/ECOLI/sequence-aa?object=EG10686-MONOMER at EcoCyc] | ||
<pre>MSDMAERLAL HEFTENAYLN YSMYVIMDRA LPFIGDGLKP VQRRIVYAMS ELGLNASAKF | <pre>MSDMAERLAL HEFTENAYLN YSMYVIMDRA LPFIGDGLKP VQRRIVYAMS ELGLNASAKF | ||
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RGRRGTLMRG LQRIDRVEID SPRRASSGDS EE</pre> | RGRRGTLMRG LQRIDRVEID SPRRASSGDS EE</pre> | ||
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!{{table heading style}} |Mol. Wt | !align=left {{table heading style}} |Mol. Wt | ||
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83.83 kDa (calc) <ref name='LIB:EcoCyc10.6'/> | 83.83 kDa (calc) <ref name='LIB:EcoCyc10.6'/> | ||
|- | |- | ||
!{{table heading style}} |pI | !align=left {{table heading style}} |pI | ||
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|- | |- | ||
!{{table heading style}} |Extinction coefficient | !align=left {{table heading style}} |Extinction coefficient | ||
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55810 - 56060 (calc based on 19 Y, 5 W, and 2 C residues) | 55810 - 56060 (calc based on 19 Y, 5 W, and 2 C residues) | ||
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!Type!!Residues!!Description!!Notes | !|Type!!Residues!!Description!!Notes | ||
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!Resource type!!Source!!Notes/Reference | !|Resource type!!Source!!Notes/Reference | ||
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!Database!!Accession!!Notes | !|Database!!Accession!!Notes | ||
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[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]]) | [http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]]) | ||
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[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10686-MONOMER EcoCyc:EG10686-MONOMER] | [http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10686-MONOMER EcoCyc:EG10686-MONOMER] | ||
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[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]]) | [http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]]) | ||
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[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P0AFI2 SwissModel:P0AFI2] | [http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P0AFI2 SwissModel:P0AFI2] | ||
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[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]]) | [http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]]) | ||
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[[uniprot:P0AFI2|UniProt:P0AFI2]] | [[uniprot:P0AFI2|UniProt:P0AFI2]] | ||
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[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]]) | [http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]]) | ||
| | | | ||
[http://pfam.sanger.ac.uk/family?acc=PF00521 PFAM:PF00521] | [http://pfam.sanger.ac.uk/family?acc=PF00521 PFAM:PF00521] | ||
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[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]]) | [http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]]) | ||
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[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417491 RefSeq:NP_417491] | [http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417491 RefSeq:NP_417491] | ||
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|- | |- | ||
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[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]]) | [http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]]) | ||
| | | | ||
[http://salilab.org/modbase/searchbyid?databaseID=P0AFI2 ModBase:P0AFI2] | [http://salilab.org/modbase/searchbyid?databaseID=P0AFI2 ModBase:P0AFI2] | ||
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[http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]]) | [http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]]) | ||
| | | | ||
[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ZVT PDB:1ZVT] | [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ZVT PDB:1ZVT] | ||
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Revision as of 02:28, 15 November 2008
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
ParC product |
|---|---|
| Synonyms |
DNA topoisomerase IV, subunit A product[1], B3019 product[2][1], ParC product[2][1] |
| Product description |
topoisomerase IV subunit A[2][3]; Component of ; dimer of topoisomerase IV subunit A[3]; topoisomerase IV[3] |
| EC number (for enzymes) | |
| edit table |
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc 11.1[3]. |
complete | |||
| GO:0006261 |
DNA-dependent DNA replication |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc 11.1[3]. |
complete | |||
| GO:0003918 |
DNA topoisomerase (ATP-hydrolyzing) activity |
IDA: Inferred from Direct Assay |
F |
required field missing | ||||
| edit table |
Interactions
| Partner Type | Partner | Notes |
|---|---|---|
|
Protein |
Subunits of dimer of topoisomerase IV subunit A |
could be indirect |
|
Protein |
Subunits of topoisomerase IV |
could be indirect |
| edit table |
See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Notes
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
|
cytoplasm |
From EcoCyc[3] | ||
| edit table |
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MSDMAERLAL HEFTENAYLN YSMYVIMDRA LPFIGDGLKP VQRRIVYAMS ELGLNASAKF KKSARTVGDV LGKYHPHGDS ACYEAMVLMA QPFSYRYPLV DGQGNWGAPD DPKSFAAMRY TESRLSKYSE LLLSELGQGT ADWVPNFDGT LQEPKMLPAR LPNILLNGTT GIAVGMATDI PPHNLREVAQ AAIALIDQPK TTLDQLLDIV QGPDYPTEAE IITSRAEIRK IYENGRGSVR MRAVWKKEDG AVVISALPHQ VSGARVLEQI AAQMRNKKLP MVDDLRDESD HENPTRLVIV PRSNRVDMDQ VMNHLFATTD LEKSYRINLN MIGLDGRPAV KNLLEILSEW LVFRRDTVRR RLNYRLEKVL KRLHILEGLL VAFLNIDEVI EIIRNEDEPK PALMSRFGLT ETQAEAILEL KLRHLAKLEE MKIRGEQSEL EKERDQLQGI LASERKMNNL LKKELQADAQ AYGDDRRSPL QEREEAKAMS EHDMLPSEPV TIVLSQMGWV RSAKGHDIDA PGLNYKAGDS FKAAVKGKSN QPVVFVDSTG RSYAIDPITL PSARGQGEPL TGKLTLPPGA TVDHMLMESD DQKLLMASDA GYGFVCTFND LVARNRAGKA LITLPENAHV MPPVVIEDAS DMLLAITQAG RMLMFPVSDL PQLSKGKGNK IINIPSAEAA RGEDGLAQLY VLPPQSTLTI HVGKRKIKLR PEELQKVTGE RGRRGTLMRG LQRIDRVEID SPRRASSGDS EE |
|---|---|
| Mol. Wt |
83.83 kDa (calc) [2] |
| pI | |
| Extinction coefficient |
55810 - 56060 (calc based on 19 Y, 5 W, and 2 C residues) |
| edit table |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
| edit table |
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
Structure
| Structures |
<beststructure>parC 562</beststructure> |
|---|---|
| Models |
View models at: |
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Espeli, O et al. (2003) Temporal regulation of topoisomerase IV activity in E. coli. Mol. Cell 11 189-201 PubMed
- ↑ Kato, J et al. (1990) New topoisomerase essential for chromosome segregation in E. coli. Cell 63 393-404 PubMed
Categories