mutM:Gene Product(s): Difference between revisions

Standard name	MutM
Synonyms	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase^[1], B3635^[2]^[1], Fpg^[2]^[1], MutM^[2]^[1]
Product description	formamidopyrimidine DNA glycosylase^[2]^[3] Formamidopyrimidine-DNA glycosylase/AP lyase; 5'-terminal deoxyribophosphodiesterase; DNA repair; GC to TA; binds Zn(II)^[4]
EC number (for enzymes)	3.2.2.23^[1]
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0019104	DNA N-glycosylase activity	PMID:2664776^[5]	IDA: Inferred from Direct Assay		F		complete
	GO:0004519	endonuclease activity	PMID:2664776^[5]	IDA: Inferred from Direct Assay		F	nicking at AP sites	complete
	GO:0003676	nucleic acid binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR010979	F	Seeded from EcoCyc (v14.0)
	GO:0003677	DNA binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015887	F	Seeded from EcoCyc (v14.0)
	GO:0003677	DNA binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F	Seeded from EcoCyc (v14.0)
	GO:0003684	damaged DNA binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012319	F	Seeded from EcoCyc (v14.0)
	GO:0003684	damaged DNA binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015886	F	Seeded from EcoCyc (v14.0)
	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_00103	F	Seeded from EcoCyc (v14.0)
	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000191	F	Seeded from EcoCyc (v14.0)
	GO:0008270	zinc ion binding	PMID:8473347^[6]	IDA: Inferred from Direct Assay		F		complete
	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000214	F	Seeded from EcoCyc (v14.0)
	GO:0046872	metal ion binding	PMID:8473347^[6]	IDA: Inferred from Direct Assay		F	Cu(II), Cd(II), Hg(II) bind the protein	complete
	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012319	F	Seeded from EcoCyc (v14.0)
	GO:0019104	DNA N-glycosylase activity	PMID:8473347^[6]	IDA: Inferred from Direct Assay		F		complete
	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015886	F	Seeded from EcoCyc (v14.0)
	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	PMID:8473347^[6]	IDA: Inferred from Direct Assay		F		complete
	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015887	F	Seeded from EcoCyc (v14.0)
	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	GOA:spec GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:4.2.99.18	F	Seeded from EcoCyc (v14.0)
	GO:0006974	response to DNA damage stimulus	PMID:1731864^[7]	IDA: Inferred from Direct Assay		P		complete
	GO:0006281	DNA repair	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_00103	P	Seeded from EcoCyc (v14.0)
	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	PMID:1731864^[7]	IDA: Inferred from Direct Assay		F		complete
	GO:0004519	endonuclease activity	PMID:8473347^[6]	IDA: Inferred from Direct Assay		F		complete
	GO:0006281	DNA repair	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000191	P	Seeded from EcoCyc (v14.0)
	GO:0019104	DNA N-glycosylase activity	PMID:1649454^[8]	EXP: Inferred from Experiment		F		complete
	GO:0006281	DNA repair	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000214	P	Seeded from EcoCyc (v14.0)
	GO:0004519	endonuclease activity	PMID:1649454^[8]	EXP: Inferred from Experiment		F		complete
	GO:0004519	endonuclease activity	PMID:1731864^[7]	IDA: Inferred from Direct Assay		F		complete
	GO:0006281	DNA repair	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015887	P	Seeded from EcoCyc (v14.0)
	GO:0006281	DNA repair	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR020629	P	Seeded from EcoCyc (v14.0)
	GO:0019104	DNA N-glycosylase activity	PMID:10862773^[9]	IDA: Inferred from Direct Assay		F		complete
	GO:0006281	DNA repair	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0234	P	Seeded from EcoCyc (v14.0)
	GO:0003684	damaged DNA binding	PMID:10862773^[9]	IDA: Inferred from Direct Assay		F		complete
	GO:0006284	base-excision repair	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012319	P	Seeded from EcoCyc (v14.0)
	GO:0006289	nucleotide-excision repair	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015886	P	Seeded from EcoCyc (v14.0)
	GO:0006974	response to DNA damage stimulus	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0227	P	Seeded from EcoCyc (v14.0)
	GO:0008152	metabolic process	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0326	P	Seeded from EcoCyc (v14.0)
	GO:0008270	zinc ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000191	F	Seeded from EcoCyc (v14.0)
	GO:0008270	zinc ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000214	F	Seeded from EcoCyc (v14.0)
	GO:0008270	zinc ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012319	F	Seeded from EcoCyc (v14.0)
	GO:0008270	zinc ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015886	F	Seeded from EcoCyc (v14.0)
	GO:0008270	zinc ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015887	F	Seeded from EcoCyc (v14.0)
	GO:0008270	zinc ion binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR020629	F	Seeded from EcoCyc (v14.0)
	GO:0008270	zinc ion binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0862	F	Seeded from EcoCyc (v14.0)
	GO:0008534	oxidized purine base lesion DNA N-glycosylase activity	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_00103	F	Seeded from EcoCyc (v14.0)
	GO:0008534	oxidized purine base lesion DNA N-glycosylase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000191	F	Seeded from EcoCyc (v14.0)
	GO:0008534	oxidized purine base lesion DNA N-glycosylase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR020629	F	Seeded from EcoCyc (v14.0)
	GO:0008534	oxidized purine base lesion DNA N-glycosylase activity	GOA:spec GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:3.2.2.23	F	Seeded from EcoCyc (v14.0)
	GO:0016829	lyase activity	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0456	F	Seeded from EcoCyc (v14.0)
	GO:0046872	metal ion binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F	Seeded from EcoCyc (v14.0)
	GO:0046872	metal ion binding	PMID:8473347^[6]	IDA: Inferred from Direct Assay		F	Seeded from EcoCyc (v14.0)
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
Protein	glpT		PMID:16606699^[10]	Experiment(s):EBI-1146365
Protein	thiI		PMID:16606699^[10]	Experiment(s):EBI-1146365
Protein	ilvI		PMID:16606699^[10]	Experiment(s):EBI-1146365
Small Molecule	PMPS	Inhibitor	PMID:8473347^[6]	Activity Assays
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Source	Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence	at EcoCyc MPELPEVETS RRGIEPHLVG ATILHAVVRN GRLRWPVSEE IYRLSDQPVL SVQRRAKYLL LELPEGWIII HLGMSGSLRI LPEELPPEKH DHVDLVMSNG KVLRYTDPRR FGAWLWTKEL EGHNVLTHLG PEPLSDDFNG EYLHQKCAKK KTAIKPWLMD NKLVVGVGNI YASESLFAAG IHPDRLASSL SLAECELLAR VIKAVLLRSI EQGGTTLKDF LQSDGKPGYF AQELQVYGRK GEPCRVCGTP IVATKHAQRA TFYCRQCQK
Length	269
Mol. Wt	30.29 kDa
pI	8.6 (calculated)
Extinction coefficient	39,420 - 40,170 (calc based on 8 Y, 5 W, and 6 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes	References
Initiator Methionine	1	Removed	UniProt:P05523
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mutM taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:EG10329-MONOMER
UniProt (EcoliWiki Page)	UniProt:P05523
PFAM (EcoliWiki Page)	PFAM:PF01149
RefSeq (EcoliWiki Page)	RefSeq:NP_418092
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 O'Connor, TR & Laval, J (1989) Physical association of the 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase of Escherichia coli and an activity nicking DNA at apurinic/apyrimidinic sites. Proc. Natl. Acad. Sci. U.S.A. 86 5222-6 PubMed
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 O'Connor, TR et al. (1993) Fpg protein of Escherichia coli is a zinc finger protein whose cysteine residues have a structural and/or functional role. J. Biol. Chem. 268 9063-70 PubMed
↑ ^7.0 ^7.1 ^7.2 Boiteux, S et al. (1992) Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization. Biochemistry 31 106-10 PubMed
↑ ^8.0 ^8.1 Michaels, ML et al. (1991) MutM, a protein that prevents G.C----T.A transversions, is formamidopyrimidine-DNA glycosylase. Nucleic Acids Res. 19 3629-32 PubMed
↑ ^9.0 ^9.1 Hazra, TK et al. (2000) Characterization of a novel 8-oxoguanine-DNA glycosylase activity in Escherichia coli and identification of the enzyme as endonuclease VIII. J. Biol. Chem. 275 27762-7 PubMed
↑ ^10.0 ^10.1 ^10.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

mutM:Gene Product(s): Difference between revisions

Revision as of 18:19, 17 June 2010

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

@@ Line 120: / Line 120: @@
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-GO:0008270
+GO:0003676
 |
-zinc ion binding
+nucleic acid binding
 |
-PMID:8473347
+GOA:interpro<br />GO_REF:0000002
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR010979
 |
 F
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
-complete
 |-
 |
 |
-GO:0046872
+GO:0003677
 |
-metal ion binding
+DNA binding
 |
-PMID:8473347
+GOA:interpro<br />GO_REF:0000002
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR015887
 |
 F
 |
-Cu(II), Cd(II), Hg(II) bind the protein
+Seeded from [[EcoCyc]] (v14.0)
 |
-complete
 |-
 |
 |
-GO:0019104
+GO:0003677
 |
-DNA N-glycosylase activity
+DNA binding
 |
-PMID:8473347
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+SP_KW:KW-0238
 |
 F
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
-complete
 |-
 |
 |
-GO:0003906
+GO:0003684
 |
-DNA-(apurinic or apyrimidinic site) lyase activity
+damaged DNA binding
 |
-PMID:8473347
+GOA:interpro<br />GO_REF:0000002
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR012319
 |
 F
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
-complete
 |-
 |
 |
-GO:0006974
+GO:0003684
 |
-response to DNA damage stimulus
+damaged DNA binding
 |
-PMID:1731864
+GOA:interpro<br />GO_REF:0000002
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR015886
 |
-P
+F
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
-complete
 |-
 |
@@ Line 219: / Line 219: @@
 DNA-(apurinic or apyrimidinic site) lyase activity
 |
-PMID:1731864
+GOA:hamap<br />GO_REF:0000020
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+HAMAP:MF_00103
 |
 F
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
-complete
 |-
 |
 |
-GO:0004519
+GO:0003906
 |
-endonuclease activity
+DNA-(apurinic or apyrimidinic site) lyase activity
 |
-PMID:8473347
+GOA:interpro<br />GO_REF:0000002
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR000191
 |
 F
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
-complete
 |-
 |
 |
-GO:0019104
+GO:0008270
 |
-DNA N-glycosylase activity
+zinc ion binding
 |
-PMID:1649454
+PMID:8473347
 |
-EXP: Inferred from Experiment
+IDA: Inferred from Direct Assay
 |
@@ Line 272: / Line 272: @@
 |
-GO:0004519
+GO:0003906
 |
-endonuclease activity
+DNA-(apurinic or apyrimidinic site) lyase activity
 |
-PMID:1649454
+GOA:interpro<br />GO_REF:0000002
 |
-EXP: Inferred from Experiment
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR000214
 |
 F
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
-complete
 |-
 |
 |
-GO:0004519
+GO:0046872
 |
-endonuclease activity
+metal ion binding
 |
-PMID:1731864
+PMID:8473347
 |
 IDA: Inferred from Direct Assay
@@ Line 303: / Line 303: @@
 F
 |
+Cu(II), Cd(II), Hg(II) bind the protein
 |
 complete
@@ Line 310: / Line 310: @@
 |
-GO:0019104
+GO:0003906
 |
-DNA N-glycosylase activity
+DNA-(apurinic or apyrimidinic site) lyase activity
 |
-PMID:10862773
+GOA:interpro<br />GO_REF:0000002
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR012319
 |
 F
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
-complete
 |-
 |
 |
-GO:0003684
+GO:0019104
 |
-damaged DNA binding
+DNA N-glycosylase activity
 |
-PMID:10862773
+PMID:8473347
 |
 IDA: Inferred from Direct Assay
@@ Line 348: / Line 348: @@
 |
-GO:0003676
+GO:0003906
 |
-nucleic acid binding
+DNA-(apurinic or apyrimidinic site) lyase activity
 |
 GOA:interpro<br />GO_REF:0000002
@@ Line 356: / Line 356: @@
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR010979
+InterPro:IPR015886
 |
 F
@@ Line 367: / Line 367: @@
 |
-GO:0003677
+GO:0003906
 |
-DNA binding
+DNA-(apurinic or apyrimidinic site) lyase activity
 |
-GOA:interpro<br />GO_REF:0000002
+PMID:8473347
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-InterPro:IPR015887
 |
 F
 |
-Seeded from [[EcoCyc]] (v14.0)
 |
+complete
 |-
 |
 |
-GO:0003677
+GO:0003906
 |
-DNA binding
+DNA-(apurinic or apyrimidinic site) lyase activity
 |
-GOA:spkw<br />SP_KW:GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0238
+InterPro:IPR015887
 |
 F
@@ Line 405: / Line 405: @@
 |
-GO:0003684
+GO:0003906
 |
-damaged DNA binding
+DNA-(apurinic or apyrimidinic site) lyase activity
 |
-GOA:interpro<br />GO_REF:0000002
+GOA:spec<br />GO_REF:0000003
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR012319
+EC:4.2.99.18
 |
 F
@@ Line 424: / Line 424: @@
 |
-GO:0003684
+GO:0006974
 |
-damaged DNA binding
+response to DNA damage stimulus
 |
-GOA:interpro<br />GO_REF:0000002
+PMID:1731864
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-InterPro:IPR015886
 |
-F
+P
 |
-Seeded from [[EcoCyc]] (v14.0)
 |
+complete
 |-
 |
 |
-GO:0003906
+GO:0006281
 |
-DNA-(apurinic or apyrimidinic site) lyase activity
+DNA repair
 |
 GOA:hamap<br />GO_REF:0000020
@@ Line 453: / Line 453: @@
 HAMAP:MF_00103
 |
-F
+P
 |
 Seeded from [[EcoCyc]] (v14.0)
@@ Line 466: / Line 466: @@
 DNA-(apurinic or apyrimidinic site) lyase activity
 |
-GOA:interpro<br />GO_REF:0000002
+PMID:1731864
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-InterPro:IPR000191
 |
 F
 |
-Seeded from [[EcoCyc]] (v14.0)
 |
+complete
 |-
 |
 |
-GO:0003906
+GO:0004519
 |
-DNA-(apurinic or apyrimidinic site) lyase activity
+endonuclease activity
 |
-GOA:interpro<br />GO_REF:0000002
+PMID:8473347
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-InterPro:IPR000214
 |
 F
 |
-Seeded from [[EcoCyc]] (v14.0)
 |
+complete
 |-
 |
 |
-GO:0003906
+GO:0006281
 |
-DNA-(apurinic or apyrimidinic site) lyase activity
+DNA repair
 |
 GOA:interpro<br />GO_REF:0000002
@@ Line 508: / Line 508: @@
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR012319
+InterPro:IPR000191
 |
-F
+P
 |
 Seeded from [[EcoCyc]] (v14.0)
@@ Line 519: / Line 519: @@
 |
-GO:0003906
+GO:0019104
 |
-DNA-(apurinic or apyrimidinic site) lyase activity
+DNA N-glycosylase activity
 |
-GOA:interpro<br />GO_REF:0000002
+PMID:1649454
 |
-IEA: Inferred from Electronic Annotation
+EXP: Inferred from Experiment
 |
-InterPro:IPR015886
 |
 F
 |
-Seeded from [[EcoCyc]] (v14.0)
 |
+complete
 |-
 |
 |
-GO:0003906
+GO:0006281
 |
-DNA-(apurinic or apyrimidinic site) lyase activity
+DNA repair
 |
 GOA:interpro<br />GO_REF:0000002
@@ Line 546: / Line 546: @@
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR015887
+InterPro:IPR000214
 |
-F
+P
 |
 Seeded from [[EcoCyc]] (v14.0)
@@ Line 557: / Line 557: @@
 |
-GO:0003906
+GO:0004519
 |
-DNA-(apurinic or apyrimidinic site) lyase activity
+endonuclease activity
 |
-GOA:spec<br />GO_REF:0000003
+PMID:1649454
 |
-IEA: Inferred from Electronic Annotation
+EXP: Inferred from Experiment
 |
-EC:4.2.99.18
 |
 F
 |
-Seeded from [[EcoCyc]] (v14.0)
 |
+complete
 |-
 |
 |
-GO:0006281
+GO:0004519
 |
-DNA repair
+endonuclease activity
 |
-GOA:hamap<br />GO_REF:0000020
+PMID:1731864
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-HAMAP:MF_00103
 |
-P
+F
 |
-Seeded from [[EcoCyc]] (v14.0)
 |
+complete
 |-
 |
@@ Line 603: / Line 603: @@
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR000191
+InterPro:IPR015887
 |
 P
@@ Line 622: / Line 622: @@
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR000214
+InterPro:IPR020629
 |
 P
@@ Line 633: / Line 633: @@
 |
-GO:0006281
+GO:0019104
 |
-DNA repair
+DNA N-glycosylase activity
 |
-GOA:interpro<br />GO_REF:0000002
+PMID:10862773
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-InterPro:IPR015887
 |
-P
+F
 |
-Seeded from [[EcoCyc]] (v14.0)
 |
+complete
 |-
 |
@@ Line 656: / Line 656: @@
 DNA repair
 |
-GOA:interpro<br />GO_REF:0000002
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR020629
+SP_KW:KW-0234
 |
 P
@@ Line 671: / Line 671: @@
 |
-GO:0006281
+GO:0003684
 |
-DNA repair
+damaged DNA binding
 |
-GOA:spkw<br />SP_KW:GO_REF:0000004
+PMID:10862773
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-SP_KW:KW-0234
 |
-P
+F
 |
-Seeded from [[EcoCyc]] (v14.0)
 |
+complete
 |-
 |

mutM:Gene Product(s): Difference between revisions

Revision as of 18:19, 17 June 2010

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

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