galE:Gene Product(s): Difference between revisions

Standard name	GalE
Synonyms	UDP-galactose-4-epimerase^[1], B0759^[2]^[1], GalD^[2]^[1], GalE^[2]^[1] , ECK0748, galD, JW0742, b0759
Product description	UDP-glucose 4-epimerase^[2]^[3]; Component of UDP-glucose 4-epimerase^[2]^[3] UDP-galactose 4-epimerase; hexose-1-phosphate uridylyltransferase^[4]
EC number (for enzymes)	5.1.3.2^[1]
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0003978	UDP-glucose 4-epimerase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005886	F	Seeded from EcoCyc (v14.0)	complete
	GO:0003978	UDP-glucose 4-epimerase activity	GOA:spec GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:5.1.3.2	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005829	cytosol	PMID:16858726^[5]	IDA: Inferred from Direct Assay		C	Seeded from EcoCyc (v14.0)	complete
	GO:0006012	galactose metabolic process	PMID:13914787^[6]	IMP: Inferred from Mutant Phenotype		P	Seeded from EcoCyc (v14.0)	complete
	GO:0006012	galactose metabolic process	PMID:7025059^[7]	IMP: Inferred from Mutant Phenotype		P		complete
	GO:0005975	carbohydrate metabolic process	PMID:7025059^[7]	IMP: Inferred from Mutant Phenotype		P		complete
	GO:0016052	carbohydrate catabolic process	PMID:7025059^[7]	IGI: Inferred from Genetic Interaction		P		Missing: with/from
	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	PMID:1821806^[8]	IDA: Inferred from Direct Assay		F		complete
	GO:0006012	galactose metabolic process	PMID:1821806^[8]	IDA: Inferred from Direct Assay		P		complete
	GO:0005737	cytoplasm	PMID:1821806^[8]	IDA: Inferred from Direct Assay		C		complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
Protein	Subunits of UDP-glucose 4-epimerase	could be indirect
Protein	rsuA		PMID:16606699^[9]	Experiment(s):EBI-1137880
Protein	yfcH		PMID:16606699^[9]	Experiment(s):EBI-1137880
Protein	nadE		PMID:16606699^[9]	Experiment(s):EBI-1137880
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MRVLVTGGSG YIGSHTCVQL LQNGHDVIIL DNLCNSKRSV LPVIERLGGK HPTFVEGDIR NEALMTEILH DHAIDTVIHF AGLKAVGESV QKPLEYYDNN VNGTLRLISA MRAANVKNFI FSSSATVYGD QPKIPYVESF PTGTPQSPYG KSKLMVEQIL TDLQKAQPDW SIALLRYFNP VGAHPSGDMG EDPQGIPNNL MPYIAQVAVG RRDSLAIFGN DYPTEDGTGV RDYIHVMDLA DGHVVAMEKL ANKPGVHIYN LGAGVGNSVL DVVNAFSKAC GKPVNYHFAP RREGDLPAYW ADASKADREL NWRVTRTLDE MAQDTWHWQS RHPQGYPD
Length	338
Mol. Wt	37.264 kDa
pI	6.3 (calculated)
Extinction coefficient	48,360 - 48,735 (calc based on 14 Y, 5 W, and 3 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes	References
Domain	3..262	PF01370 NAD dependent epimerase/dehydratase family		PMID:19920124^[10]
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=galE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:49176045	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:945354	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0002575	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P09147	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:EG10362	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG10362	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:945354	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120000355	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB0357	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
↑ SOFFER, RL (1961) Enzymatic expression of genetic units of function concerned with galactose metabolism in Escherichia coli. J. Bacteriol. 82 471-8 PubMed
↑ ^7.0 ^7.1 ^7.2 Fietta, A et al. (1981) R-factor-mediated suppression of the galactose-sensitive phenotype of Escherichia coli K-12 galE Mutants. Plasmid 6 78-85 PubMed
↑ ^8.0 ^8.1 ^8.2 Vorgias, CE et al. () Overexpression and purification of the galactose operon enzymes from Escherichia coli. Protein Expr. Purif. 2 330-8 PubMed
↑ ^9.0 ^9.1 ^9.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

galE:Gene Product(s): Difference between revisions

Latest revision as of 20:29, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

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 |{{Sub}}[[#Localization |Localization]]
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+|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
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 ==Nomenclature==
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 |-
-!{{table heading style}} |Standard name
+!align=left {{table heading style}} |Standard name
-|
+||
-GalE product
+GalE
 |-
-!{{table heading style}} |Synonyms
+!align=left {{table heading style}} |Synonyms
-|
+||
-UDP-galactose-4-epimerase<ref name='LIB:Riley_2006'/>, B0759<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GalD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GalE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
+''UDP-galactose-4-epimerase<ref name='LIB:Riley_2006'/>, B0759<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GalD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GalE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0748, galD, JW0742, b0759''
 |-
-!{{table heading style}} |Product description
+!align=left {{table heading style}} |Product description
-|
+||
-UDP-glucose 4-epimerase monomer<ref name='LIB:EcoCyc10.6'/>; UDP-glucose 4-epimerase monomer<ref name='LIB:EcoCyc11.1'/>; Component of [[:Category:Complex:UDP-glucose 4-epimerase|UDP-glucose 4-epimerase]]<ref name='LIB:EcoCyc10.6'/>; UDP-glucose 4-epimerase<ref name='LIB:EcoCyc10.6'/>; UDP-glucose 4-epimerase<ref name='LIB:EcoCyc11.1'/>
+UDP-glucose 4-epimerase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;
+Component of [[:Category:Complex:UDP-glucose 4-epimerase|UDP-glucose 4-epimerase]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
+UDP-galactose 4-epimerase; hexose-1-phosphate uridylyltransferase<ref name='LIB:EcoGene'/>
 |-
-!{{table heading style}} |EC number (for enzymes)
+!align=left {{table heading style}} |EC number (for enzymes)
-|
+||
-*[http://www.brenda.uni-koeln.de/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2]<ref name='LIB:Riley_2006'/>
+* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2]<ref name='LIB:Riley_2006'/>
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-{{Product_nomenclature_help}}
 <protect><!--Nomenclature_notes--></protect>
 ===Notes===
@@ Line 48: / Line 68: @@
 ==Function==
+{{BacktoTop}}
 <protect>
-===Gene Ontology===
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 |- {{table_heading_style}}
-!Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
+!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
 |-
 |
 |
-GO:0005737
+GO:0003978
 |
-cytoplasm
+UDP-glucose 4-epimerase activity
 |
+GOA:interpro<br />GO_REF:0000002
 |
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR005886
 |
-C
+F
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
+Seeded from [[EcoCyc]] (v14.0)
 |
-required fields missing
+complete
 |-
 |
 |
-GO:0006012
+GO:0003978
 |
-galactose metabolic process
+UDP-glucose 4-epimerase activity
 |
+GOA:spec<br />GO_REF:0000003
 |
+IEA: Inferred from Electronic Annotation
 |
+EC:5.1.3.2
 |
-P
+F
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
+Seeded from [[EcoCyc]] (v14.0)
 |
-required fields missing
+complete
 |-
 |
 |
-GO:0009242
+GO:0005829
 |
-colanic acid biosynthetic process
+cytosol
 |
+PMID:16858726
 |
+IDA: Inferred from Direct Assay
 |
 |
-P
+C
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
+Seeded from [[EcoCyc]] (v14.0)
 |
-required fields missing
+complete
 |-
 |
 |
-GO:0016052
+GO:0006012
 |
-carbohydrate catabolic process
+galactose metabolic process
 |
+PMID:13914787
 |
+IMP: Inferred from Mutant Phenotype
 |
 |
 P
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
+Seeded from [[EcoCyc]] (v14.0)
 |
-required fields missing
+complete
 |-
 |
 |
-GO:0009435
+GO:0006012
 |
-NAD biosynthetic process
+galactose metabolic process
 |
+PMID:7025059
 |
+IMP: Inferred from Mutant Phenotype
 |
 |
 P
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
 |
-required fields missing
+complete
 |-
 |
 |
-GO:0009269
+GO:0005975
 |
-response to desiccation
+carbohydrate metabolic process
 |
+PMID:7025059
 |
+IMP: Inferred from Mutant Phenotype
 |
 |
 P
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
 |
-required fields missing
+complete
 |-
 |
 |
-GO:0042280
+GO:0016052
 |
-cell surface antigen activity, host-interacting
+carbohydrate catabolic process
 |
+PMID:7025059
 |
+IGI: Inferred from Genetic Interaction
 |
 |
-F
+P
 |
-Seeded from Riley et  al 2006 <ref name='LIB:Riley_2006'/>.
 |
-required fields missing
+Missing: with/from
 |-
 |
 |
-GO:0030113
+GO:0016857
 |
-capsule (sensu Bacteria)
+racemase and epimerase activity, acting on carbohydrates and derivatives
 |
+PMID:1821806
 |
+IDA: Inferred from Direct Assay
 |
 |
-C
+F
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
 |
-required fields missing
+complete
-|-class='sortbottom'
+|-
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-===Interactions===
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-|- {{table heading style}}
-!Partner Type!!Partner!!Notes
-|-
-|
-Protein
 |
-Subunits of [[:Category:Complex:UDP-glucose 4-epimerase|UDP-glucose 4-epimerase]]
-|
-could be indirect
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-===Notes===
-==Localization==
-<protect><!--Localization_notes--></protect>
-===Notes===
-==Structure and Physical Properties==
-<protect>
-===Physical Properties===
-<!--box uid=421aa90e079fa326b6494f812ad13e79..X469fcb932da2e-->
-<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. ***  -->
-{|{{Prettytable}}
-|-
-!{{table heading style}} |Sequence
 |
-[http://biocyc.org/ECOLI/sequence-aa?object=UDPGLUCEPIM-MONOMER at EcoCyc]
+GO:0006012
-<pre>MRVLVTGGSG YIGSHTCVQL LQNGHDVIIL DNLCNSKRSV LPVIERLGGK HPTFVEGDIR
-NEALMTEILH DHAIDTVIHF AGLKAVGESV QKPLEYYDNN VNGTLRLISA MRAANVKNFI
-FSSSATVYGD QPKIPYVESF PTGTPQSPYG KSKLMVEQIL TDLQKAQPDW SIALLRYFNP
-VGAHPSGDMG EDPQGIPNNL MPYIAQVAVG RRDSLAIFGN DYPTEDGTGV RDYIHVMDLA
-DGHVVAMEKL ANKPGVHIYN LGAGVGNSVL DVVNAFSKAC GKPVNYHFAP RREGDLPAYW
-ADASKADREL NWRVTRTLDE MAQDTWHWQS RHPQGYPD</pre>
-|-
-!{{table heading style}} |Mol. Wt
 |
-.27 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
+galactose metabolic process
-|-
-!{{table heading style}} |pI
 |
-.28<ref name='LIB:EcoCyc10.6'/>
+PMID:1821806
-|-
-!{{table heading style}} |Extinction coefficient
 |
-- 48735 (calc based on 14 Y, 5 W, and 3 C residues)
+IDA: Inferred from Direct Assay
-|-
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-!Type!!Residues!!Description!!Notes
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-|- {{table heading style}}
-!Structure Type!!Organism!!Accession!!Residues covered!!Notes
-|-
 |
-X-RAY DIFFRACTION
 |
-Escherichia coli
+P
 |
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2UDP 2UDP] UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL
 |
+complete
+|-
 |
-|-
 |
-X-RAY DIFFRACTION
+GO:0005737
 |
-Escherichia coli
+cytoplasm
 |
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XEL 1XEL] UDP-GALACTOSE 4-EPIMERASE FROM ESCHERICHIA COLI
+PMID:1821806
 |
+IDA: Inferred from Direct Assay
 |
-|-
 |
-X-RAY DIFFRACTION
+C
 |
-Escherichia coli
 |
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UDC 1UDC] STRUCTURE OF UDP-GALACTOSE-4-EPIMERASE COMPLEXED WITH UDP-MANNOSE
+complete
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21293.H46aa42291caff&page=21293&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</span> || || || || || || || ||
+|}
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.H46aa42291caff-->
+<span id="Interactions"></span><big>'''Interactions'''</big>
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.J46aa426b39cda-->
+<!--
+******************************************************************************************
+*
+*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
+*
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+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="J46aa426b39cda"  class=" tableEdit Product_interactions_table dataTable"
+|- {{table heading style}}
+!|Partner Type!!Partner!!Notes!!References!!Evidence
+|-
 |
+Protein
 |
+Subunits of [[:Category:Complex:UDP-glucose 4-epimerase|UDP-glucose 4-epimerase]]
-|-
 |
-X-RAY DIFFRACTION
+could be indirect
 |
-Escherichia coli
-|
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UDB 1UDB] STRUCTURE OF UDP-GALACTOSE-4-EPIMERASE COMPLEXED WITH UDP-4-DEOXY-4-FLUORO-ALPHA-D-GLUCOSE
 |
+|-
 |
+Protein
-|-
 |
-X-RAY DIFFRACTION
+rsuA<br />
 |
-Escherichia coli
 |
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UDA 1UDA] STRUCTURE OF UDP-GALACTOSE-4-EPIMERASE COMPLEXED WITH UDP-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE
+PMID:16606699
 |
+Experiment(s):EBI-1137880<br />
+|-
 |
+Protein
-|-
 |
-X-RAY DIFFRACTION
+yfcH<br />
 |
-Escherichia coli
 |
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NAI 1NAI] UDP-GALACTOSE 4-EPIMERASE FROM ESCHERICHIA COLI, OXIDIZED
+PMID:16606699
 |
+Experiment(s):EBI-1137880<br />
+|-
 |
+Protein
-|-
 |
-X-RAY DIFFRACTION
+nadE<br />
 |
-Escherichia coli
 |
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NAH 1NAH] UDP-GALACTOSE 4-EPIMERASE FROM ESCHERICHIA COLI, REDUCED
+PMID:16606699
 |
+Experiment(s):EBI-1137880<br />
-|
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21293.J46aa426b39cda&page=21293&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || ||
+|}
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.J46aa426b39cda-->
+<!--Function_notes--></protect>
+===Notes===
+==Localization==
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.Q46a7d4273b14b-->
+<!--
+******************************************************************************************
+*
+*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
+*
+****************************************************************************************** -->{{Product_localization_help}}
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="Q46a7d4273b14b"  class=" tableEdit Product_localization_table"
+|- {{table heading style}}
+!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21293.Q46a7d4273b14b&page=21293&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || ||
+|}
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.Q46a7d4273b14b-->
+<protect><!--Localization_notes--></protect>
+===Notes===
+==Structure and Physical Properties==
+{{BacktoTop}}
+<protect>
+<span id="Sequence"></span><big>'''Physical Properties'''</big>
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.T46aa426d54e5c-->
+<!--
+******************************************************************************************
+*
+*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
+*
+****************************************************************************************** -->{{Product_physical_properties_help}}
+{|   id="T46aa426d54e5c"  class=" tableEdit Product_phys_prop_table"
 |-
-|
+!align=left {{table heading style}} |Name
-X-RAY DIFFRACTION
+||
-|
-Escherichia coli
-|
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1LRL 1LRL] Crystal Structure of UDP-Galactose 4-Epimerase Mutant Y299C Complexed with UDP-Glucose
-|
-|
 |-
-|
+!align=left {{table heading style}} |Sequence
-X-RAY DIFFRACTION
+||
+[http://biocyc.org/ECOLI/sequence-aa?object=UDPGLUCEPIM-MONOMER at EcoCyc]
-|
+<pre>MRVLVTGGSG YIGSHTCVQL LQNGHDVIIL DNLCNSKRSV LPVIERLGGK HPTFVEGDIR
-Escherichia coli
+NEALMTEILH DHAIDTVIHF AGLKAVGESV QKPLEYYDNN VNGTLRLISA MRAANVKNFI
+FSSSATVYGD QPKIPYVESF PTGTPQSPYG KSKLMVEQIL TDLQKAQPDW SIALLRYFNP
-|
+VGAHPSGDMG EDPQGIPNNL MPYIAQVAVG RRDSLAIFGN DYPTEDGTGV RDYIHVMDLA
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1LRK 1LRK] Crystal Structure of Escherichia coli UDP-Galactose 4-Epimerase Mutant Y299C Complexed with UDP-N-acetylglucosamine
+DGHVVAMEKL ANKPGVHIYN LGAGVGNSVL DVVNAFSKAC GKPVNYHFAP RREGDLPAYW
-|
+ADASKADREL NWRVTRTLDE MAQDTWHWQS RHPQGYPD</pre>
-|
 |-
-|
+!align=left {{table heading style}} |Length
-X-RAY DIFFRACTION
+||
-|
-Escherichia coli
-|
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1LRJ 1LRJ] Crystal Structure of E. coli UDP-Galactose 4-Epimerase Complexed with UDP-N-Acetylglucosamine
-|
-|
 |-
-|
+!align=left {{table heading style}} |Mol. Wt
-X-RAY DIFFRACTION
+||
+.264 kDa
-|
-Escherichia coli
-|
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KVU 1KVU] UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL
-|
-|
 |-
-|
+!align=left {{table heading style}} |pI
-X-RAY DIFFRACTION
+||
+.3 (calculated)
-|
-Escherichia coli
-|
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KVT 1KVT] UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL
-|
-|
 |-
+!align=left {{table heading style}} |Extinction coefficient
+||
+,360 - 48,735 (calc based on 14 Y, 5 W, and 3 C residues)
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21293.T46aa426d54e5c&page=21293&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> ||
+|}
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.T46aa426d54e5c-->
+<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table>
+<tr align="left" valign="top">
+<td><!--box uid=421aa90e079fa326b6494f812ad13e79.21293.D46aa426db0285-->
+<!--
+******************************************************************************************
+*
+*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
+*
+****************************************************************************************** -->{{Product_domains_motifs_help}}
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="D46aa426db0285"  class=" tableEdit Product_motif_table dataTable"
+|- {{table heading style}}
+!|Type!!Residues!!Description!!Notes!!References
+|-
 |
-X-RAY DIFFRACTION
+Domain
 |
-Escherichia coli
+..262
 |
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KVS 1KVS] UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL
+[http://pfam.janelia.org/family/PF01370 PF01370  NAD dependent epimerase/dehydratase family]
 |
 |
+PMID:19920124
-|-
-|
+|- class="tableEdit_footer"
-X-RAY DIFFRACTION
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21293.D46aa426db0285&page=21293&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || ||
+|}
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.D46aa426db0285--></td>
+<td>
+<!-- motifs column 2-->
-|
+<motif_map/>
-Escherichia coli
+</td>
+</tr>
-|
+</table>
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KVR 1KVR] UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL
-|
+<table><tr valign='top'><td>
+<span id='Structure'></span><big>'''Structure'''</big><br />
-|
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.X46aa426e07634-->
+<!--
-|-
+******************************************************************************************
-|
+*
-X-RAY DIFFRACTION
+*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
+*
-|
+****************************************************************************************** -->{{Product_structure_help}}
-Escherichia coli
+{|   id="X46aa426e07634"  class=" tableEdit Product_structure_table"
-|
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KVQ 1KVQ] UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL
-|
-|
 |-
-|
+!align=left {{table heading style}} |Structures
-X-RAY DIFFRACTION
+||
+<beststructure>
-|
+gene=galE
-Escherichia coli
+taxon=562,83333
+</beststructure>
-|
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1A9Z 1A9Z] UDP-GALACTOSE 4-EPIMERASE MUTANT S124A/Y149F COMPLEXED WITH UDP-GALACTOSE
-|
-|
 |-
-|
+!align=left {{table heading style}} |Models
-X-RAY DIFFRACTION
+||
+View models at:
-|
+* [http://www.proteinmodelportal.org/query/uniprot/P09147 Protein Model Portal]
-Escherichia coli
+* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P09147 PSI-PRED (P09147)]
+* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P09147 Genomes TO Protein (P09147)] (GTOP)
-|
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1A9Y 1A9Y] UDP-GALACTOSE 4-EPIMERASE MUTANT S124A/Y149F COMPLEXED WITH UDP-GLUCOSE
+|- class="tableEdit_footer"
-|
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21293.X46aa426e07634&page=21293&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> ||
-|
-|-class='sortbottom'
-|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..X469fcb935a5bb&page=&pagename={{FULLPAGENAMEE}} edit table] || || || ||
 |}
-<!--box uid=421aa90e079fa326b6494f812ad13e79..X469fcb935a5bb-->
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.X46aa426e07634-->
-{{Product_structure_help}}
-<!--Structure_notes--></protect>
+</td><td></protect>
+==== Structure figures ====
+<protect><!--          ***** PLEASE DO NOT EDIT BELOW THIS LINE *****         -->
+</td><tr><table><!--Structure_notes--></protect>
 ===Notes===
 ==Gene Product Resources==
-<!--box uid=421aa90e079fa326b6494f812ad13e79..T469fcb97c4e00-->
+{{BacktoTop}}
-<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. ***  -->
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.A46aa427e3e5b8-->
-{|class = 'sortable' {{Prettytable}} id='36896'
+<!--
+******************************************************************************************
+*
+*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
+*
+****************************************************************************************** -->{{Product_resources_help}}
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="A46aa427e3e5b8"  class=" tableEdit Product_resource_table"
 |- {{table_heading_style}}
-!Resource type!!Source!!Notes/Reference
+!|Resource type!!Source!!Notes/Reference
-|-class='sortbottom'
-|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..T469fcb97c4e00&page=&pagename={{FULLPAGENAMEE}} edit table] || ||
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21293.A46aa427e3e5b8&page=21293&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || ||
 |}
-<!--box uid=421aa90e079fa326b6494f812ad13e79..T469fcb97c4e00-->
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.A46aa427e3e5b8-->
-{{Product_resources_help}}
 <protect><!--Resources_notes--></protect>
 ===Notes===
 ==Accessions in Other Databases==
-<!--box uid=421aa90e079fa326b6494f812ad13e79..V469fcb97d92a4-->
+{{BacktoTop}}
-<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. ***  -->
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.E46aa427e89f16-->
-{|class = 'sortable' {{Prettytable}} id='36897'
+<!--
+******************************************************************************************
+*
+*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
+*
+****************************************************************************************** -->{{Gene_accessions_help}}
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="E46aa427e89f16"  class=" tableEdit Gene_accessions_table"
 |- {{table_heading_style}}
-!Database!!Accession!!Notes
+!|Database!!Accession!!Notes
 |-
+|
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/49176045 GI:49176045]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/NP_415280.3 GeneID:945354]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[[ASAP]]
+|
+ASAP:ABE-0002575
+|
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
+|-
 |
-[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
+[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
 |
-[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=UDPGLUCEPIM-MONOMER EcoCyc:UDPGLUCEPIM-MONOMER]
+[http://www.uniprot.org/uniprot/P09147 UniProtKB/Swiss-Prot:P09147]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
+[[EcoCyc]]
 |
-[http://www.expasy.ch/cgi-bin/sprot-search-ac?P09147 UniProt:P09147]
+EcoCyc:EG10362
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://www.sanger.ac.uk/Software/Pfam/ PFAM] ([[PFAM|EcoliWiki Page]])
+[[EcoGene]]
 |
-[http://www.sanger.ac.uk/cgi-bin/Pfam/getacc?PF01370 PFAM:PF01370]
+EcoGene:EG10362
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
 |
-[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415280 RefSeq:NP_415280]
+[http://www.ncbi.nlm.nih.gov/gene?term=945354 GeneID:945354]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
+[[RegulonDB]]
 |
-[http://salilab.org/modbase/searchbyid?databaseID=P09147 ModBase:P09147]
+RegulonDB:ECK120000355
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]])
+[[EchoBASE]]
 |
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1A9Y PDB:1A9Y]
+EchoBASE:EB0357
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
-|-class='sortbottom'
-|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..V469fcb97d92a4&page=&pagename={{FULLPAGENAMEE}} edit table] || ||
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21293.E46aa427e89f16&page=21293&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table]</span> || ||
 |}
-<!--box uid=421aa90e079fa326b6494f812ad13e79..V469fcb97d92a4-->
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.E46aa427e89f16-->
-{{Product_accessions_help}}
 <protect><!--Accessions_notes--></protect>
 ===Notes===
@@ Line 590: / Line 613: @@
 ==Links==
+{{BacktoTop}}
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.M46a7d440b0933-->
+<!--
+******************************************************************************************
+*
+*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
+*
+****************************************************************************************** -->
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="M46a7d440b0933"  class=" tableEdit Links_table"
+|- {{table_heading_style}}
+!|Name!!URL!!Comments
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21293.M46a7d440b0933&page=21293&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table]</span> || ||
+|}
+<!--box uid=421aa90e079fa326b6494f812ad13e79.21293.M46a7d440b0933-->
 <noinclude>
 ==References==
+{{BacktoTop}}
 {{RefHelp}}
-<references/>
+<references />
 __NOTOC__
-[[Category:GO:0005737]][[Category:GO:0006012]][[Category:GO:0009242]][[Category:GO:0016052]][[Category:GO:0009435]][[Category:GO:0009269]][[Category:GO:0042280]][[Category:GO:0030113]][[Category:Complex:UDP-glucose 4-epimerase]]</noinclude>
+===Categories===
+{{BacktoTop}}
+[[Category:Proteins]]
+[[Category:RefGenome_Annotated_Gene]]

galE:Gene Product(s): Difference between revisions

Latest revision as of 20:29, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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