uvrC:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
UvrC |
|---|---|
| Synonyms |
excinuclease UvrABC, endonuclease subunit[1], B1913[2][1], UvrC[2][1] , ECK1912, JW1898, b1913 |
| Product description |
excinuclease ABC, subunit C; repair of UV damage to DNA[2][3]; Component of UvrABC Nucleotide Excision Repair Complex[2][3] Excision nuclease subunit C; repair of UV damage to DNA; multicopy causes mucoidy[4] |
| EC number (for enzymes) |
|
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004518 |
nuclease activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004518 |
nuclease activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004518 |
nuclease activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004518 |
nuclease activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004518 |
nuclease activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005622 |
intracellular |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005622 |
intracellular |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006289 |
nucleotide-excision repair |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006289 |
nucleotide-excision repair |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006289 |
nucleotide-excision repair |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006289 |
nucleotide-excision repair |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006974 |
response to DNA damage stimulus |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009380 |
excinuclease repair complex |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009381 |
excinuclease ABC activity |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009381 |
excinuclease ABC activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009432 |
SOS response |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009432 |
SOS response |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of UvrABC Nucleotide Excision Repair Complex |
could be indirect |
||
|
Protein |
aceE |
Experiment(s):EBI-880917 | ||
|
Protein |
lpdA |
Experiment(s):EBI-880917, EBI-887152 | ||
|
Protein |
rplA |
Experiment(s):EBI-880917, EBI-887152 | ||
|
Protein |
rplB |
Experiment(s):EBI-880917, EBI-887152 | ||
|
Protein |
rplC |
Experiment(s):EBI-880917, EBI-887152 | ||
|
Protein |
rpsB |
Experiment(s):EBI-880917 | ||
|
Protein |
rpsD |
Experiment(s):EBI-880917, EBI-887152 | ||
|
Protein |
rpsG |
Experiment(s):EBI-880917, EBI-887152 | ||
|
Protein |
rpsK |
Experiment(s):EBI-880917 | ||
|
Protein |
rpsM |
Experiment(s):EBI-880917, EBI-887152 | ||
|
Protein |
yfiB |
Experiment(s):EBI-880917 | ||
|
Protein |
yjeF |
Experiment(s):EBI-880917 | ||
|
Protein |
rpsC |
Experiment(s):EBI-880917, EBI-887152 | ||
|
Protein |
ddpA |
Experiment(s):EBI-887152 | ||
|
Protein |
yfgF |
Experiment(s):EBI-887152 | ||
|
Protein |
cspC |
Experiment(s):EBI-887152 | ||
|
Protein |
glnK |
Experiment(s):EBI-887152 | ||
|
Protein |
hupA |
Experiment(s):EBI-887152 | ||
|
Protein |
pntA |
Experiment(s):EBI-887152 | ||
|
Protein |
rplD |
Experiment(s):EBI-887152 | ||
|
Protein |
rplI |
Experiment(s):EBI-887152 | ||
|
Protein |
rplM |
Experiment(s):EBI-887152 | ||
|
Protein |
rplN |
Experiment(s):EBI-887152 | ||
|
Protein |
rplS |
Experiment(s):EBI-887152 | ||
|
Protein |
rplT |
Experiment(s):EBI-887152 | ||
|
Protein |
rplU |
Experiment(s):EBI-887152 | ||
|
Protein |
rplV |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsA |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsE |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsF |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsH |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsJ |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsN |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsO |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsR |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsS |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsT |
Experiment(s):EBI-887152 | ||
|
Protein |
sucA |
Experiment(s):EBI-887152 | ||
|
Protein |
sucB |
Experiment(s):EBI-887152 | ||
|
Protein |
yfiF |
Experiment(s):EBI-887152 | ||
|
Protein |
yhbY |
Experiment(s):EBI-887152 | ||
|
Protein |
rplY |
Experiment(s):EBI-887152 | ||
|
Protein |
rpmB |
Experiment(s):EBI-887152 | ||
|
Protein |
rpsL |
Experiment(s):EBI-887152 | ||
|
Protein |
rpmB |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsS |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsH |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplT |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplS |
LCMS(ID Probability):99.6 MALDI(Z-score):5.210219 | ||
|
Protein |
rpsL |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplU |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsN |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsT |
LCMS(ID Probability):99.6 | ||
|
Protein |
hupA |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsF |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsM |
LCMS(ID Probability):99.0 MALDI(Z-score):17.053160 | ||
|
Protein |
rplA |
LCMS(ID Probability):99.6 MALDI(Z-score):8.116641 | ||
|
Protein |
rpsC |
LCMS(ID Probability):99.6 MALDI(Z-score):29.295881 | ||
|
Protein |
rpsO |
LCMS(ID Probability):99.4 | ||
|
Protein |
rplM |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplB |
LCMS(ID Probability):99.6 MALDI(Z-score):8.451958 | ||
|
Protein |
rpsD |
LCMS(ID Probability):99.6 MALDI(Z-score):36.225093 | ||
|
Protein |
yjeF |
MALDI(Z-score):17.053160 | ||
|
Protein |
sucB |
LCMS(ID Probability):99.6 | ||
|
Protein |
sucA |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplD |
LCMS(ID Probability):99.2 MALDI(Z-score):3.129348 | ||
|
Protein |
ddpA |
LCMS(ID Probability):99.0 | ||
|
Protein |
yhbY |
LCMS(ID Probability):99.6 | ||
|
Protein |
pntA |
LCMS(ID Probability):99.0 | ||
|
Protein |
yfiF |
LCMS(ID Probability):99.6 | ||
|
Protein |
yfiB |
MALDI(Z-score):17.053160 | ||
|
Protein |
yfgF |
LCMS(ID Probability):99.0 | ||
|
Protein |
glnK |
LCMS(ID Probability):99.0 | ||
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MYDAGGTVIY VGKAKDLKKR LSSYFRSNLA SRKTEALVAQ IQQIDVTVTH TETEALLLEH NYIKLYQPRY NVLLRDDKSY PFIFLSGDTH PRLAMHRGAK HAKGEYFGPF PNGYAVRETL ALLQKIFPIR QCENSVYRNR SRPCLQYQIG RCLGPCVEGL VSEEEYAQQV EYVRLFLSGK DDQVLTQLIS RMETASQNLE FEEAARIRDQ IQAVRRVTEK QFVSNTGDDL DVIGVAFDAG MACVHVLFIR QGKVLGSRSY FPKVPGGTEL SEVVETFVGQ FYLQGSQMRT LPGEILLDFN LSDKTLLADS LSELAGRKIN VQTKPRGDRA RYLKLARTNA ATALTSKLSQ QSTVHQRLTA LASVLKLPEV KRMECFDISH TMGEQTVASC VVFDANGPLR AEYRRYNITG ITPGDDYAAM NQVLRRRYGK AIDDSKIPDV ILIDGGKGQL AQAKNVFAEL DVSWDKNHPL LLGVAKGADR KAGLETLFFE PEGEGFSLPP DSPALHVIQH IRDESHDHAI GGHRKKRAKV KNTSSLETIE GVGPKRRQML LKYMGGLQGL RNASVEEIAK VPGISQGLAE KIFWSLKH |
| Length |
588 |
| Mol. Wt |
65.717 kDa |
| pI |
9.2 (calculated) |
| Extinction coefficient |
42,290 - 43,165 (calc based on 21 Y, 2 W, and 7 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 5.19 5.20 5.21 5.22 5.23 5.24 5.25 5.26 5.27 5.28 5.29 5.30 5.31 5.32 5.33 5.34 5.35 5.36 5.37 5.38 5.39 5.40 5.41 5.42 5.43 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 6.18 6.19 6.20 6.21 6.22 6.23 6.24 6.25 6.26 6.27 6.28 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ 7.0 7.1 7.2 7.3 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0003677 ! DNA binding
- GO:0004518 ! nuclease activity
- GO:0005622 ! intracellular
- GO:0005737 ! cytoplasm
- GO:0006281 ! DNA repair
- GO:0006289 ! nucleotide-excision repair
- GO:0006974 ! cellular response to DNA damage stimulus
- GO:0009380 ! excinuclease repair complex
- GO:0009381 ! excinuclease ABC activity
- GO:0009432 ! SOS response
- Proteins
