sucC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

SucC

Synonyms

succinyl-CoA synthetase, beta subunit[1], B0728[2][1], SucC[2][1], β subunit[2][1] , ECK0716, JW0717, b0728

Product description

succinyl-CoA synthetase, β subunit[2][3];

Component of succinyl-CoA synthetase[2][3]

Succinyl CoA synthase beta-subunit; acid-inducible[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0000287

magnesium ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0460

F

Seeded from EcoCyc (v14.0)

complete

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005809

F

Seeded from EcoCyc (v14.0)

complete

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005811

F

Seeded from EcoCyc (v14.0)

complete

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011761

F

Seeded from EcoCyc (v14.0)

complete

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013816

F

Seeded from EcoCyc (v14.0)

complete

GO:0004775

succinate-CoA ligase (ADP-forming) activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00558

F

Seeded from EcoCyc (v14.0)

complete

GO:0004775

succinate-CoA ligase (ADP-forming) activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:6.2.1.5

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00558

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011761

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013816

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0006099

tricarboxylic acid cycle

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00558

P

Seeded from EcoCyc (v14.0)

complete

GO:0006099

tricarboxylic acid cycle

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0816

P

Seeded from EcoCyc (v14.0)

complete

GO:0016874

ligase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0436

F

Seeded from EcoCyc (v14.0)

complete

GO:0030145

manganese ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0464

F

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc (v14.0)

complete

GO:0004775

succinate-CoA ligase (ADP-forming) activity

PMID:3543212[5]

IMP: Inferred from Mutant Phenotype

F

complete

GO:0006099

tricarboxylic acid cycle

PMID:3543212[5]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0005575

cellular component

127.0.0.1 14:29, 17 February 2015 (CST)

ND: No biological Data available

C

Missing: reference

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of succinyl-CoA synthetase

could be indirect

Protein

sucB

PMID:16606699[6]

Experiment(s):EBI-1137818

Protein

sucD

PMID:16606699[6]

Experiment(s):EBI-1137818

Protein

zwf

PMID:16606699[6]

Experiment(s):EBI-1137818

Protein

sdhA

PMID:16606699[6]

Experiment(s):EBI-1137818

Protein

prs

PMID:16606699[6]

Experiment(s):EBI-1137818

Protein

rsuA

PMID:16606699[6]

Experiment(s):EBI-1137818

Protein

umuC

PMID:16606699[6]

Experiment(s):EBI-1137818

Protein

rplI

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsR

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsS

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

ahpC

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

gadB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

yfiD

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

recA

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsA

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

dps

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

infB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

miaB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

eno

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

clpB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

pflB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsJ

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

dnaJ

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

metE

PMID:19402753[7]

LCMS(ID Probability):98.8

Protein

ibpA

PMID:19402753[7]

LCMS(ID Probability):99.5

Protein

frsA

PMID:19402753[7]

LCMS(ID Probability):99.5

Protein

yaiL

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

sucD

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

asnA

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

upp

PMID:19402753[7]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MNLHEYQAKQ LFARYGLPAP VGYACTTPRE AEEAASKIGA GPWVVKCQVH AGGRGKAGGV
KVVNSKEDIR AFAENWLGKR LVTYQTDANG QPVNQILVEA ATDIAKELYL GAVVDRSSRR
VVFMASTEGG VEIEKVAEET PHLIHKVALD PLTGPMPYQG RELAFKLGLE GKLVQQFTKI
FMGLATIFLE RDLALIEINP LVITKQGDLI CLDGKLGADG NALFRQPDLR EMRDQSQEDP
REAQAAQWEL NYVALDGNIG CMVNGAGLAM GTMDIVKLHG GEPANFLDVG GGATKERVTE
AFKIILSDDK VKAVLVNIFG GIVRCDLIAD GIIGAVAEVG VNVPVVVRLE GNNAELGAKK
LADSGLNIIA AKGLTDAAQQ VVAAVEGK
Length

388

Mol. Wt

41.392 kDa

pI

5.3 (calculated)

Extinction coefficient

26,930 - 27,555 (calc based on 7 Y, 3 W, and 5 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

262..382

PF00549 CoA-ligase

PMID:19920124[8]

Domain

2..203

PF08442 ATP-grasp domain

PMID:19920124[8]

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=sucC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128703

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945312

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002483

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A836

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10981

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10981

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945312

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000970

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0974

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Buck, D et al. (1986) Cloning and expression of the succinyl-CoA synthetase genes of Escherichia coli K12. J. Gen. Microbiol. 132 1753-62 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 7.21 7.22 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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