rpoB:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
RpoB |
|---|---|
| Synonyms |
RNA polymerase, beta subunit[1], B3987[2][1], Stl[2][1], Stv[2][1], TabD[2][1], SdgB[2][1], Ron[2][1], Rif[2][1], NitB[2][1], GroN[2][1], FtsR[2][1], RpoB[2][1] , ECK3978, ftsR, groN, JW3950, mbrD?, nitB, rif, ron, sdgB, stl, stv, tabD, tabG, b3987 |
| Product description |
RNA polymerase, β subunit[2][3]; Component of RNA polymerase, core enzyme[2][3]; RNA polymerase sigma 24[2][3]; RNA polymerase sigma 38[2][3]; RNA polymerase sigma32[2]; RNA polymerase sigma 32[3]; RNA polymerase sigma54[2]; RNA polymerase sigma 54[3]; RNA polymerase sigma70[2]; RNA polymerase sigma 70[3]; RNA polymerase sigma 19[3]; RNA polymerase sigma 28[3] RNA polymerase, beta subunit; binds Zn(II)[4] |
| EC number (for enzymes) | |
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:spec |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003899 |
DNA-directed RNA polymerase activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0006350 |
transcription |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006351 |
transcription, DNA-dependent |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006351 |
transcription, DNA-dependent |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016020 |
membrane |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016740 |
transferase activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016779 |
nucleotidyltransferase activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0032549 |
ribonucleoside binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of RNA polymerase, core enzyme |
could be indirect |
||
|
Protein |
rplB |
Experiment(s):EBI-1147178 | ||
|
Protein |
ompL |
Experiment(s):EBI-1147178 | ||
|
Protein |
rpoC |
Experiment(s):EBI-1147178, EBI-1147184 | ||
|
Protein |
sdhA |
Experiment(s):EBI-1147178 | ||
|
Protein |
atpD |
Experiment(s):EBI-879304 | ||
|
Protein |
cca |
Experiment(s):EBI-879304 | ||
|
Protein |
cysB |
Experiment(s):EBI-879304 | ||
|
Protein |
hupA |
Experiment(s):EBI-879304, EBI-883170 | ||
|
Protein |
rho |
Experiment(s):EBI-879304 | ||
|
Protein |
rplB |
Experiment(s):EBI-879304 | ||
|
Protein |
rpoA |
Experiment(s):EBI-879304, EBI-879354, EBI-883170, EBI-883271 | ||
|
Protein |
rpoH |
Experiment(s):EBI-879304, EBI-879426 | ||
|
Protein |
rpoN |
Experiment(s):EBI-879304, EBI-879445, EBI-883645 | ||
|
Protein |
rpsC |
Experiment(s):EBI-879304 | ||
|
Protein |
rpsJ |
Experiment(s):EBI-879304, EBI-883170 | ||
|
Protein |
secA |
Experiment(s):EBI-879304 | ||
|
Protein |
tufA |
Experiment(s):EBI-879304 | ||
|
Protein |
yahO |
Experiment(s):EBI-879304 | ||
|
Protein |
ybhF |
Experiment(s):EBI-879304 | ||
|
Protein |
xdhD |
Experiment(s):EBI-883170 | ||
|
Protein |
cycA |
Experiment(s):EBI-883170 | ||
|
Protein |
mutL |
Experiment(s):EBI-883170 | ||
|
Protein |
pstB |
Experiment(s):EBI-883170 | ||
|
Protein |
rhsE |
Experiment(s):EBI-883170 | ||
|
Protein |
ribD |
Experiment(s):EBI-883170 | ||
|
Protein |
rplD |
Experiment(s):EBI-883170 | ||
|
Protein |
rplL |
Experiment(s):EBI-883170 | ||
|
Protein |
rplV |
Experiment(s):EBI-883170 | ||
|
Protein |
rpmG |
Experiment(s):EBI-883170 | ||
|
Protein |
ldcA |
Experiment(s):EBI-883170 | ||
|
Protein |
rnfC |
Experiment(s):EBI-883170 | ||
|
Protein |
rpsE |
Experiment(s):EBI-883170 | ||
|
Protein |
rpsF |
Experiment(s):EBI-883170 | ||
|
Protein |
rpsN |
Experiment(s):EBI-883170 | ||
|
Protein |
rpsT |
Experiment(s):EBI-883170 | ||
|
Protein |
rpsU |
Experiment(s):EBI-883170 | ||
|
Protein |
torR |
Experiment(s):EBI-883170 | ||
|
Protein |
yidE |
Experiment(s):EBI-883170 | ||
|
Protein |
rplK |
Experiment(s):EBI-883170 | ||
|
Protein |
rpsN |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpmG |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsT |
LCMS(ID Probability):99.6 | ||
|
Protein |
ribD |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsF |
LCMS(ID Probability):99.6 | ||
|
Protein |
hupA |
LCMS(ID Probability):99.0 MALDI(Z-score):17.053160 | ||
|
Protein |
tufB |
MALDI(Z-score):21.953813 | ||
|
Protein |
secA |
LCMS(ID Probability):91.9 MALDI(Z-score):17.703872 | ||
|
Protein |
rho |
MALDI(Z-score):24.930275 | ||
|
Protein |
rpsJ |
LCMS(ID Probability):99.6 MALDI(Z-score):5.643283 | ||
|
Protein |
rplB |
MALDI(Z-score):20.662050 | ||
|
Protein |
rplD |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsU |
LCMS(ID Probability):99.6 | ||
|
Protein |
nusG |
LCMS(ID Probability):99.6 MALDI(Z-score):36.899044 | ||
|
Protein |
rpoC |
LCMS(ID Probability):99.6 MALDI(Z-score):14.117317 | ||
|
Protein |
rpoS |
LCMS(ID Probability):99.0 MALDI(Z-score):9.798043 | ||
|
Protein |
rapA |
MALDI(Z-score):22.372697 | ||
|
Protein |
torR |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplL |
LCMS(ID Probability):99.6 | ||
|
Protein |
Subunits of RNA polymerase sigma 24 |
could be indirect |
||
|
Protein |
Subunits of RNA polymerase sigma 38 |
could be indirect |
||
|
Protein |
Subunits of RNA polymerase sigma32 |
could be indirect |
||
|
Protein |
Subunits of RNA polymerase sigma54 |
could be indirect |
||
|
Protein |
Subunits of RNA polymerase sigma70 |
could be indirect |
||
|
Protein |
Subunits of RNA polymerase sigma 19 |
could be indirect |
||
|
Protein |
Subunits of RNA polymerase sigma 28 |
could be indirect |
| |
| edit table |
</protect>
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
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Notes
Structure and Physical Properties
<protect>
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MVYSYTEKKR IRKDFGKRPQ VLDVPYLLSI QLDSFQKFIE QDPEGQYGLE AAFRSVFPIQ SYSGNSELQY VSYRLGEPVF DVQECQIRGV TYSAPLRVKL RLVIYEREAP EGTVKDIKEQ EVYMGEIPLM TDNGTFVING TERVIVSQLH RSPGVFFDSD KGKTHSSGKV LYNARIIPYR GSWLDFEFDP KDNLFVRIDR RRKLPATIIL RALNYTTEQI LDLFFEKVIF EIRDNKLQME LVPERLRGET ASFDIEANGK VYVEKGRRIT ARHIRQLEKD DVKLIEVPVE YIAGKVVAKD YIDESTGELI CAANMELSLD LLAKLSQSGH KRIETLFTND LDHGPYISET LRVDPTNDRL SALVEIYRMM RPGEPPTREA AESLFENLFF SEDRYDLSAV GRMKFNRSLL REEIEGSGIL SKDDIIDVMK KLIDIRNGKG EVDDIDHLGN RRIRSVGEMA ENQFRVGLVR VERAVKERLS LGDLDTLMPQ DMINAKPISA AVKEFFGSSQ LSQFMDQNNP LSEITHKRRI SALGPGGLTR ERAGFEVRDV HPTHYGRVCP IETPEGPNIG LINSLSVYAQ TNEYGFLETP YRKVTDGVVT DEIHYLSAIE EGNYVIAQAN SNLDEEGHFV EDLVTCRSKG ESSLFSRDQV DYMDVSTQQV VSVGASLIPF LEHDDANRAL MGANMQRQAV PTLRADKPLV GTGMERAVAV DSGVTAVAKR GGVVQYVDAS RIVIKVNEDE MYPGEAGIDI YNLTKYTRSN QNTCINQMPC VSLGEPVERG DVLADGPSTD LGELALGQNM RVAFMPWNGY NFEDSILVSE RVVQEDRFTT IHIQELACVS RDTKLGPEEI TADIPNVGEA ALSKLDESGI VYIGAEVTGG DILVGKVTPK GETQLTPEEK LLRAIFGEKA SDVKDSSLRV PNGVSGTVID VQVFTRDGVE KDKRALEIEE MQLKQAKKDL SEELQILEAG LFSRIRAVLV AGGVEAEKLD KLPRDRWLEL GLTDEEKQNQ LEQLAEQYDE LKHEFEKKLE AKRRKITQGD DLAPGVLKIV KVYLAVKRRI QPGDKMAGRH GNKGVISKIN PIEDMPYDEN GTPVDIVLNP LGVPSRMNIG QILETHLGMA AKGIGDKINA MLKQQQEVAK LREFIQRAYD LGADVRQKVD LSTFSDEEVM RLAENLRKGM PIATPVFDGA KEAEIKELLK LGDLPTSGQI RLYDGRTGEQ FERPVTVGYM YMLKLNHLVD DKMHARSTGS YSLVTQQPLG GKAQFGGQRF GEMEVWALEA YGAAYTLQEM LTVKSDDVNG RTKMYKNIVD GNHQMEPGMP ESFNVLLKEI RSLGINIELE DE |
| Length |
1,342 |
| Mol. Wt |
150.635 kDa |
| pI |
5.0 (calculated) |
| Extinction coefficient |
86,070 - 86,945 (calc based on 43 Y, 4 W, and 7 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Weerasekera, R et al. (2007) Interactome and interface protocol (2IP): a novel strategy for high sensitivity topology mapping of protein complexes. Proteomics 7 3835-52 PubMed
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
- ↑ 7.0 7.1 7.2 7.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 8.13 8.14 8.15 8.16 8.17 8.18 8.19 8.20 8.21 8.22 8.23 8.24 8.25 8.26 8.27 8.28 8.29 8.30 8.31 8.32 8.33 8.34 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 9.00 9.01 9.02 9.03 9.04 9.05 9.06 9.07 9.08 9.09 9.10 9.11 9.12 9.13 9.14 9.15 9.16 9.17 9.18 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ 10.0 10.1 10.2 10.3 10.4 10.5 10.6 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0003677 ! DNA binding
- GO:0003899 ! DNA-directed 5'-3' RNA polymerase activity
- GO:0005515 ! protein binding
- GO:0006350 ! transcription
- GO:0006351 ! transcription, DNA-templated
- GO:0016020 ! membrane
- GO:0016740 ! transferase activity
- GO:0016779 ! nucleotidyltransferase activity
- GO:0032549 ! ribonucleoside binding
- Proteins
- RefGenome Annotated Gene
