rnpA:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
RnpA |
|---|---|
| Synonyms |
protein C5 component of RNase P[1], B3704[2][1], RnpA[2][1], C5[2][1], Rnp[2][1] , ECK3696, JW3681, b3704 |
| Product description |
RNase P protein component; processes tRNA, 4.5S RNA[2][3]; RNase P, C5 protein component; involved in tRNA and 4.5S RNA-processing[4] |
| EC number (for enzymes) | |
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
C |
Seeded from Riley et al 2006 [1]. |
Missing: evidence, reference | ||||
| GO:0000049 |
tRNA binding |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0000049 |
tRNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0001682 |
tRNA 5'-leader removal |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004518 |
nuclease activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004519 |
endonuclease activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004526 |
ribonuclease P activity |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004526 |
ribonuclease P activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0004526 |
ribonuclease P activity |
GOA:spec |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0008033 |
tRNA processing |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0008033 |
tRNA processing |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016787 |
hydrolase activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006396 |
RNA processing |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0001682 |
tRNA 5'-leader removal |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of RNase P |
could be indirect |
||
|
Protein |
rplB |
Experiment(s):EBI-1146535 | ||
|
Protein |
rpsD |
Experiment(s):EBI-1146535 | ||
|
Protein |
cybC |
Experiment(s):EBI-1146535 | ||
|
Protein |
yqgF |
Experiment(s):EBI-1146535 | ||
|
Protein |
dnaK |
Experiment(s):EBI-1146535 | ||
|
Protein |
aceF |
Experiment(s):EBI-879914 | ||
|
Protein |
deaD |
Experiment(s):EBI-879914 | ||
|
Protein |
lpdA |
Experiment(s):EBI-879914 | ||
|
Protein |
ppk |
Experiment(s):EBI-879914 | ||
|
Protein |
pssA |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
rho |
Experiment(s):EBI-879914 | ||
|
Protein |
rplA |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
rplB |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
rplC |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
rpsA |
Experiment(s):EBI-879914 | ||
|
Protein |
rpsB |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
rpsC |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
rpsD |
Experiment(s):EBI-879914 | ||
|
Protein |
rpsE |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
rpsG |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
rpsH |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
spoT |
Experiment(s):EBI-879914 | ||
|
Protein |
ycbY |
Experiment(s):EBI-879914 | ||
|
Protein |
ycfL |
Experiment(s):EBI-879914 | ||
|
Protein |
rluB |
Experiment(s):EBI-879914 | ||
|
Protein |
yfiF |
Experiment(s):EBI-879914 | ||
|
Protein |
clpA |
Experiment(s):EBI-879914 | ||
|
Protein |
rpsM |
Experiment(s):EBI-879914, EBI-884810 | ||
|
Protein |
hupA |
Experiment(s):EBI-884810 | ||
|
Protein |
rplD |
Experiment(s):EBI-884810 | ||
|
Protein |
rplF |
Experiment(s):EBI-884810 | ||
|
Protein |
rplI |
Experiment(s):EBI-884810 | ||
|
Protein |
rplK |
Experiment(s):EBI-884810 | ||
|
Protein |
rplL |
Experiment(s):EBI-884810 | ||
|
Protein |
rplM |
Experiment(s):EBI-884810 | ||
|
Protein |
rplN |
Experiment(s):EBI-884810 | ||
|
Protein |
rplO |
Experiment(s):EBI-884810 | ||
|
Protein |
rplP |
Experiment(s):EBI-884810 | ||
|
Protein |
rplQ |
Experiment(s):EBI-884810 | ||
|
Protein |
rplR |
Experiment(s):EBI-884810 | ||
|
Protein |
rplS |
Experiment(s):EBI-884810 | ||
|
Protein |
rplT |
Experiment(s):EBI-884810 | ||
|
Protein |
rplU |
Experiment(s):EBI-884810 | ||
|
Protein |
rplV |
Experiment(s):EBI-884810 | ||
|
Protein |
rplX |
Experiment(s):EBI-884810 | ||
|
Protein |
rpmC |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsF |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsI |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsJ |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsK |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsN |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsO |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsP |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsR |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsT |
Experiment(s):EBI-884810 | ||
|
Protein |
rpsU |
Experiment(s):EBI-884810 | ||
|
Protein |
rpmC |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpmB |
LCMS(ID Probability):99.6 | ||
|
Protein |
rho |
MALDI(Z-score):36.660582 | ||
|
Protein |
rplN |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplO |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplP |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsH |
LCMS(ID Probability):99.6 MALDI(Z-score):11.401811 | ||
|
Protein |
rplS |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplT |
LCMS(ID Probability):99.6 | ||
|
Protein |
hupA |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsI |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsP |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsT |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsJ |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsF |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsN |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplX |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsS |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsM |
LCMS(ID Probability):99.6 MALDI(Z-score):15.423817 | ||
|
Protein |
rpsA |
MALDI(Z-score):26.730017 | ||
|
Protein |
rplR |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplU |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplA |
LCMS(ID Probability):99.6 MALDI(Z-score):22.431914 | ||
|
Protein |
rpsR |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplM |
LCMS(ID Probability):99.6 MALDI(Z-score):2.512944 | ||
|
Protein |
rplB |
LCMS(ID Probability):99.6 MALDI(Z-score):38.309788 | ||
|
Protein |
rplF |
LCMS(ID Probability):99.4 | ||
|
Protein |
rpsK |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsC |
LCMS(ID Probability):99.6 MALDI(Z-score):38.220722 | ||
|
Protein |
rplQ |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsD |
LCMS(ID Probability):99.6 MALDI(Z-score):36.752884 | ||
|
Protein |
ppk |
MALDI(Z-score):26.012222 | ||
|
Protein |
clpA |
MALDI(Z-score):23.165660 | ||
|
Protein |
rlmL |
MALDI(Z-score):38.289465 | ||
|
Protein |
rpsO |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsU |
LCMS(ID Probability):99.6 | ||
|
Protein |
yhbY |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplD |
LCMS(ID Probability):99.6 MALDI(Z-score):2.762093 | ||
|
Protein |
pnp |
MALDI(Z-score):20.141615 | ||
|
Protein |
pssA |
LCMS(ID Probability):99.6 MALDI(Z-score):28.707857 | ||
|
Protein |
infC |
LCMS(ID Probability):99.6 | ||
|
Protein |
rluC |
MALDI(Z-score):18.733516 | ||
|
Protein |
yfiF |
MALDI(Z-score):32.084556 | ||
|
Protein |
rluB |
LCMS(ID Probability):92.5 MALDI(Z-score):29.121433 | ||
|
Protein |
deaD |
MALDI(Z-score):21.050659 | ||
|
Protein |
ycfL |
MALDI(Z-score):17.053160 | ||
|
Protein |
rplL |
LCMS(ID Probability):99.6 | ||
| edit table |
</protect>
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
|
plasma membrane |
From EcoCyc[3] |
| ||
| edit table |
<protect></protect>
Notes
Structure and Physical Properties
<protect>
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MVKLAFPREL RLLTPSQFTF VFQQPQRAGT PQITILGRLN SLGHPRIGLT VAKKNVRRAH ERNRIKRLTR ESFRLRQHEL PAMDFVVVAK KGVADLDNRA LSEALEKLWR RHCRLARGS |
| Length |
119 |
| Mol. Wt |
13.789 kDa |
| pI |
12.3 (calculated) |
| Extinction coefficient |
5,500 - 5,625 (calc based on 0 Y, 1 W, and 1 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
<protect></protect>
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Bothwell, AL et al. (1976) Nucleotide sequence and in vitro processing of a precursor molecule to Escherichia coli 4.5 S RNA. J. Biol. Chem. 251 7709-16 PubMed
- ↑ Chang, S & Carbon, J (1975) The nucleotide sequence of a precursor to the glycine- and threonine-specific transfer ribonucleic acids of Escherichia coli. J. Biol. Chem. 250 5542-55 PubMed
- ↑ 7.0 7.1 7.2 7.3 7.4 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 8.13 8.14 8.15 8.16 8.17 8.18 8.19 8.20 8.21 8.22 8.23 8.24 8.25 8.26 8.27 8.28 8.29 8.30 8.31 8.32 8.33 8.34 8.35 8.36 8.37 8.38 8.39 8.40 8.41 8.42 8.43 8.44 8.45 8.46 8.47 8.48 8.49 8.50 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 9.00 9.01 9.02 9.03 9.04 9.05 9.06 9.07 9.08 9.09 9.10 9.11 9.12 9.13 9.14 9.15 9.16 9.17 9.18 9.19 9.20 9.21 9.22 9.23 9.24 9.25 9.26 9.27 9.28 9.29 9.30 9.31 9.32 9.33 9.34 9.35 9.36 9.37 9.38 9.39 9.40 9.41 9.42 9.43 9.44 9.45 9.46 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0005737 ! cytoplasm
- GO:0000049 ! tRNA binding
- GO:0001682 ! tRNA 5'-leader removal
- GO:0003723 ! RNA binding
- GO:0004518 ! nuclease activity
- GO:0004519 ! endonuclease activity
- GO:0004526 ! ribonuclease P activity
- GO:0008033 ! tRNA processing
- GO:0016787 ! hydrolase activity
- GO:0006396 ! RNA processing
- Proteins
