PMID:794064
| Citation |
Bothwell, AL, Garber, RL and Altman, S (1976) Nucleotide sequence and in vitro processing of a precursor molecule to Escherichia coli 4.5 S RNA. J. Biol. Chem. 251:7709-16 |
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| Abstract |
A precursor molecule to the stable 4.5 S RNA species of Escherichia coli has been found to accumulate at 42 degrees in a strain thermosensitive for the function of ribonuclease P. The precursor molecule is 130 nucleotides long. Twenty-two extra nucleotides, starting with pppGp, precede the mature sequence at its 5' terminus. At least 1 extra uridine residue can be found at the 3' terminus. The precursor to 4.5 S RNA is cleaved in vitro by RNase P to generate a 5' end identical to that of the mature 4.5 S RNA. |
| Links | |
| Keywords |
Base Sequence; Escherichia coli/metabolism; Hydrogen Bonding; Molecular Weight; Nucleic Acid Conformation; Oligoribonucleotides/analysis; RNA, Bacterial/metabolism; Ribonucleases/metabolism |
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