prs:Gene

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Nomenclature Location(s) and DNA Sequence Sequence Features Alleles and Phenotypes Genetic Interactions Genetic Resources Accessions Links References Suggestions

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

prs

Mnemonic

PRPP synthase

Synonyms

prsA, ECK1195, b1207, JW1198, dnaR[1][2], dnaR

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

MG1655

27.16 minutes 

MG1655: 1261098..1260151
<gbrowseImage> name=NC_000913:1260151..1261098 source=MG1655 preset=GeneLocation </gbrowseImage>

REL606

NC_012967: 1261078..1262025
<gbrowseImage> name=NC_012967:1261078..1262025 source=REL606 preset=GeneLocation </gbrowseImage>

BW2952

NC_012759: 1148872..1149819
<gbrowseImage> name=NC_012759:1148872..1149819 source=BW2952 preset=GeneLocation </gbrowseImage>

W3110

 

W3110: 1263452..1262505
<gbrowseImage> name=NC_007779:1262505..1263452 source=W3110 preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes

Coding Start (SO:0000323)

MG1655

1260154

Edman degradation

PMID:9298646[3]
PMID:11248028[4]


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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

prsD129A

D129A

(in mutant PRSA1)

Strain variation; seeded from UniProt:P0A717

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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes

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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference

Plasmid clone

Shigen

PMID:16769691[5]

Status:

Primer 1:

Primer 2:

12A3

Kohara Phage

Genobase

PMID:3038334[6]

4D10

Kohara Phage

Genobase

PMID:3038334[6]

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:EG10774

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10774

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000765

Escherichia coli str. K-12 substr. MG1655

NCBI (EcoliWiki Page)

GeneID:945772

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0767

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0004054

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. Link, AJ et al. (1997) Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12. Electrophoresis 18 1259-313 PubMed
  4. Karzai, AW & Sauer, RT (2001) Protein factors associated with the SsrA.SmpB tagging and ribosome rescue complex. Proc. Natl. Acad. Sci. U.S.A. 98 3040-4 PubMed
  5. Kitagawa, M et al. (2005) Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. DNA Res. 12 291-9 PubMed
  6. 6.0 6.1 Kohara, Y et al. (1987) The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50 495-508 PubMed

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