ppiB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

PpiB

Synonyms

peptidyl-prolyl cis-trans isomerase B (rotamase B)[1], B0525[2][1], PpiB[2][1] , ECK0518, JW0514, b0525

Product description

peptidyl-prolyl cis-trans isomerase B (rotamase B)[2][3]

Peptidylprolyl-cis-trans-isomerase B, rotamase[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003755

peptidyl-prolyl cis-trans isomerase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002130

F

Seeded from EcoCyc (v14.0)

complete

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020892

F

Seeded from EcoCyc (v14.0)

complete

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:5.2.1.8

F

Seeded from EcoCyc (v14.0)

complete

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0697

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0006457

protein folding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002130

P

Seeded from EcoCyc (v14.0)

complete

GO:0006457

protein folding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020892

P

Seeded from EcoCyc (v14.0)

complete

GO:0006457

protein folding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0697

P

Seeded from EcoCyc (v14.0)

complete

GO:0016853

isomerase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0413

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

pta

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

mukB

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

putA

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

clpX

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

yifE

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

lacZ

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

rumB

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

yfbU

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

rpoB

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

rplN

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

accC

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

dadA

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

dnaK

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

ydcS

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

glpD

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

hflK

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

pflB

PMID:16606699[5]

Experiment(s):EBI-1137072

Protein

fucK

PMID:15690043[6]

Experiment(s):EBI-894121

Protein

hflB

PMID:15690043[6]

Experiment(s):EBI-894121

Protein

rhsC

PMID:15690043[6]

Experiment(s):EBI-894121

Protein

yhjU

PMID:15690043[6]

Experiment(s):EBI-894121

Protein

bcsG

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

ftsH

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

rhsC

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

fucK

PMID:19402753[7]

LCMS(ID Probability):99.0

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm

Cytoplasm

PMID:9268657[8]

EchoLocation:ppiB


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MVTFHTNHGD IVIKTFDDKA PETVKNFLDY CREGFYNNTI FHRVINGFMI QGGGFEPGMK
QKATKEPIKN EANNGLKNTR GTLAMARTQA PHSATAQFFI NVVDNDFLNF SGESLQGWGY
CVFAEVVDGM DVVDKIKGVA TGRSGMHQDV PKEDVIIESV TVSE
Length

164

Mol. Wt

18.152 kDa

pI

5.6 (calculated)

Extinction coefficient

9,970 - 10,220 (calc based on 3 Y, 1 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

1..162

PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

PMID:19920124[9]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=ppiB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128509

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:949038

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0001806

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P23869

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10758

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10758

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:949038

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000749

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0751

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  7. ↑ 7.0 7.1 7.2 7.3 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ Edwards, KJ et al. (1997) Crystal structure of cytoplasmic Escherichia coli peptidyl-prolyl isomerase: evidence for decreased mobility of loops upon complexation. J. Mol. Biol. 271 258-65 PubMed
  9. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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