plaP:Gene Product(s)

Standard name	PlaP
Synonyms	predicted amino-acid transporter^[1], B2014^[2]^[1], YeeF^[2]^[1] , PlaP, ECK2008, JW5330, b2014
Product description	YeeF amino acid APC transporter^[2]^[3] Required for swarming phenotype, function unknown; predicted transporter^[4]
EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1003	C	Seeded from EcoCyc (v14.0)	complete
	GO:0006810	transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004841	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006810	transport	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0813	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006865	amino acid transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002293	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006865	amino acid transport	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0029	P	Seeded from EcoCyc (v14.0)	complete
	GO:0015171	amino acid transmembrane transporter activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002293	F	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002293	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004841	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-9909	C	Seeded from EcoCyc (v14.0)	complete
	GO:0055085	transmembrane transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002293	P	Seeded from EcoCyc (v14.0)	complete
	GO:0055085	transmembrane transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004841	P	Seeded from EcoCyc (v14.0)	complete
	GO:0015489	putrescine transmembrane transporter activity	PMID:21266585^[5]	IGI: Inferred from Genetic Interaction	UniProtKB:P0AFK4 UniProtKB:P0AFK6 UniProtKB:P0AFK9 UniProtKB:P0AFR9 UniProtKB:P21169 UniProtKB:P21170 UniProtKB:P60651 UniProtKB:P69874 UniProtKB:P76108 UniProtKB:P77156 UniProtKB:P77795	F	see Fig 4.	complete
	GO:0048870	cell motility	PMID:21266585^[5]	IGI: Inferred from Genetic Interaction	UniProtKB:P0AFK4 UniProtKB:P0AFK6 UniProtKB:P0AFK9 UniProtKB:P0AFR9 UniProtKB:P21169 UniProtKB:P21170 UniProtKB:P60651 UniProtKB:P69874 UniProtKB:P76108 UniProtKB:P77156 UniProtKB:P77795	P		complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source
plasma membrane	C-terminus localized in the cytoplasm with 12 predicted transmembrane domains	Daley et al. (2005) ^[6]
plasma membrane			From EcoCyc^[3]
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MTMSHNVTPN TSRVELRKTL TLVPVVMMGL AYMQPMTLFD TFGIVSGLTD GHVPTAYAFA LIAILFTALS YGKLVRRYPS AGSAYTYAQK SISPTVGFMV GWSSLLDYLF APMINILLAK IYFEALVPSI PSWMFVVALV AFMTAFNLRS LKSVANFNTV IVVLQVVLIA VILGMVVYGV FEGEGAGTLA STRPFWSGDA HVIPMITGAT ILCFSFTGFD GISNLSEETK DAERVIPRAI FLTALIGGMI FIFATYFLQL YFPDISRFKD PDASQPEIML YVAGKAFQVG ALIFSTITVL ASGMAAHAGV ARLMYVMGRD GVFPKSFFGY VHPKWRTPAM NIILVGAIAL LAINFDLVMA TALINFGALV AFTFVNLSVI SQFWIREKRN KTLKDHFQYL FLPMCGALTV GALWVNLEES SMVLGLIWAA IGLIYLACVT KSFRNPVPQY EDVA
Length	454
Mol. Wt	49.771 kDa
pI	9.0 (calculated)
Extinction coefficient	63,830 - 64,205 (calc based on 17 Y, 7 W, and 3 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes	References
Domain	22..438	PF00324 Amino acid permease		PMID:19920124^[7]
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<motif_map/>

Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yeeF taxon=562,83333 </beststructure>

Models

View models at:

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</protect>

Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:90111370	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:946533	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0006696	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P0AA47	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:EG11896	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG11896	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:946533	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001826	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1842	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 Kurihara, S et al. (2011) A novel putrescine importer required for type 1 pili-driven surface motility induced by extracellular putrescine in Escherichia coli K-12. J. Biol. Chem. 286 10185-92 PubMed
↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

plaP:Gene Product(s)

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

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