hyuA:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
HyuA |
|---|---|
| Synonyms |
D-stereospecific phenylhydantoinase[1], B2873[2][1], YgeZ[2][1], HyuA[2][1] , ECK2869, JW2841, ygeZ, b2873 |
| Product description |
Component of phenylhydantoinase[3] D-stereospecific phenylhydantoinase; physiological function unknown[4] |
| EC number (for enzymes) | |
| edit table |
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Notes
HyuA will also hydrolyze hydantoin, but the activity on that substrate is lower than hydrolysis of 
, which is a hydantoin derivative with an aromatic side chain at the 5′ position.[5]
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded from Riley et al 2006 [1].
|
Missing: with/from | |||
| GO:0016812 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0016812 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0046872 |
metal ion binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of phenylhydantoinase |
|||
|
Protein |
ydcW |
Experiment(s):EBI-1144172 | ||
|
Protein |
groL |
Experiment(s):EBI-1144172 | ||
|
Protein |
self |
homotetramer |
gel-filtration | |
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MEFAMRVLIK NGTVVNADGQ AKQDLLIESG IVRQLGNNIS PQLPYEEIDA TGCYVFPGGV DVHTHFNIDV GIARSCDDFF TGTRAAACGG TTTIIDHMGF GPNGCRLRHQ LEVYRGYAAH KAVIDYSFHG VIQHINHAIL DEIPMIVEEG LSSFKLYLTY QYKLNDDEVL QALRRLHESG ALTTVHPEND AAIASKRAEF IAAGLTAPRY HALSRPLECE AEAIARMINL AQIAGNAPLY IVHLSNGLGL DYLRLARANH QPVWVETCPQ YLLLDERSYD TEDGMKFILS PPLRNVREQD KLWCGISDGA IDVVATDHCT FSMAQRLQIS KGDFSRCPNG LPGVENRMQL LFSSGVMTGR ITPERFVELT SAMPARLFGL WPQKGLLAPG SDGDVVIIDP RQSQQIQHRH LHDNADYSPW EGFTCQGAIV RTLSRGETIF CDGTFTGKAG RGRFLRRKPF VPPVL |
| Length |
465 |
| Mol. Wt |
51.504 kDa |
| pI |
6.6 (calculated) |
| Extinction coefficient |
42,860 - 44,235 (calc based on 14 Y, 4 W, and 11 C residues) |
| edit table |
Domains/Motifs/Modification Sites
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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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<motif_map/> |
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Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
|
Purification protocol |
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|
Antibody |
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| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 5.3 5.4 Kim, GJ et al. (2000) Functional expression and characterization of the two cyclic amidohydrolase enzymes, allantoinase and a novel phenylhydantoinase, from Escherichia coli. J. Bacteriol. 182 7021-8 PubMed
- ↑ Riley, M et al. (2006) Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. 34 1-9 PubMed
- ↑ 7.0 7.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
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